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Background. Glioblastoma (GBM) is the most common primary malignant brain tumor in adults, characterized by aggressive growth and a dismal prognosis. Interleukin-33 (IL-33) and its receptor ST2 have emerged as regulators of glioma growth, but their exact function in tumorigenesis has not been deciphered. Indeed, previous studies on IL-33 in cancer have yielded somewhat opposing results as to wheth

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New-generation single-layer polytetrafluorethylene (PTFE-) or polyurethane (PU-) covered stent (CS) for the treatment of coronary artery perforation (CAP) during PCI offer high procedural efficacy. To evaluate the comparative long-term safety and efficacy of both devices. This is a multicenter pooled analysis of individual data of patients with CAP undergoing implantation of single-layer PTFE-CS o

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This study addresses the impact of witnessing different types of school bullying on Turkish school students who are bystanders. The primary aim is to investigate how the type of bullying (direct/indirect; ostracism/devaluation) affects the perception of bullying and the roles witnesses take. Additionally, we explore whether gender, global state self-esteem, and identification with one’s school acc

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Purpose: Agriculture innovation systems (AIS) examine the complex socio-technical and institutional aspects affecting sustainable agriculture. However, it is predominantly constrained to the formal sector activities in the high-income countries (HICs). The informal sector actors play a major role in the agricultural sector of low- and middle-income countries (LMICs), such as India, by innovating a

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The advances in understanding and producing heavy and super-heavy elements is the subject of this topical collection. The main covered subjects are: the description of the theory, developments of super-heavies and the determination of the Island of Stability as well as the role of these nuclei as part of the r-process scenario. The accurate determination of reaction processes are crucial to enable

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To a large degree, economic metrics and mechanisms underpin the design of adaptation policies. Such a focus has undesired consequences on the effectiveness of adaptation measures as well as on our ability to prevent incommensurable losses. The article puts forward four strategic changes in adaptation policy that shift the focus away from markets and toward community-level visions of what a liveabl

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The main objective of this study was to evaluate heavy metal contamination in volcanic and calcareous soils within Morocco’s semi-arid regions, focusing on the relationship between unique soil types and contamination dynamics. Using geographic information systems (GIS), statistical analyses, and several pollution indices, including the geoaccumulation index (Igeo), enrichment factor (EF), contamin

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Moisture damages lead to significant costs and impact indoor environments negatively. Identifying their occurrence patterns is crucial for the implementation of preventive or mitigative measures, though it remains highly challenging due to the complex interplay of multidimensional variables. This study aims to identify primary moisture damage profiles in Swedish buildings and evaluate their preval

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We comment on the consequences of the target article for language evolution research. We propose that the default assumption should be that of language-readiness in extinct hominins, and the integration of different types of available evidence from multiple disciplines should be used to assess the likely extent of the realization of this readiness. The role of archaeological evidence should be rec

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Objectives To study neutrophil gelatinase-associated lipocalin (NGAL) levels in peripheral blood in SLE, and to propose a mechanism by which neutrophils secrete NGAL on stimulation with immune complexes (IC). Methods NGAL was measured by ELISA in two independent Swedish SLE cohorts acting as exploratory and validation cohort (n=124 and n=308, respectively), disease controls (n=38) and healthy cont

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Many artificial systems simulate the physiological state of the human gastrointestinal tract (GIT) and its separate compartments. These systems have the biorelevant media and imitate the physical forces and transit times of the GIT compartments, however, they lack the food-related and within-compartmental regulations and thus issues with translation of the data obtained to clinics arise. We aimed

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It is increasingly recognized that feelings of incompleteness and not just right experiences are important emotional and sensory processes underpinning obsessive-compulsive disorder (OCD). Such experiences refer to uncomfortable sensations that something is not right or not in its proper order, and they are typically accompanied by urges to perform behavioral or mental actions until it feels just

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This chapter examines how multinational corporations communicatively navigate moral responsibility during geopolitical crises, focusing on the war in Ukraine. As corporations increasingly are expected to engage with social and political issues, their actions, or inactions, are interpreted as moral stances. We contend that a feminist ethics of care offers a compelling approach through which to unde

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The rationale for this Editorial and the Special Feature Issue (SFI) it introduces is the conviction that money and monetary system design are largely overlooked in debates concerning sustainability. Modern monies (i.e., conventional sovereign fiat currencies) and aspects of them (such as their issuance, functions, and features) tend to be taken for granted as self-evident foundations for the orga

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Review of Jan Bruér (2024), Jazz i Sverige – de första hundra åren [Jazz in Sweden – the first hundred years].

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En biografi om Amanda Brandt (1833–1915), dotter till en hovslagare och en fattig föräldralös från Västerås, Sverige, som levde ett extraordinärt liv. När hon var sjutton år försökte en av Sveriges mest berömda författare kasta misstankar på henne för en stöld som han själv hade begått. Hon turnerade i Tyskland som sopran och skådespelerska. Vid 27 års ålder fick hon sitt första barn med den värld A biography of Amanda Brandt (1833–1915), a farrier’s daughter and a poor orphan from Västerås, Sweden, who led an extraordinary life. When she was seventeen, one of Sweden’s most famous authors tried to cast suspicion on her for a theft he himself had committed. She toured Germany as a soprano singer and actress. At 27, she had her first child with the world-famous African American Shakespearean

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Background: Adverse skin reactions to continuous glucose monitors (CGMs) and devices for continuous subcutaneous insulin infusions (CSIIs) (“diabetes medical devices” (MDs)) are well known. However, epidemiological studies on prevalence and skin rash details are lacking. The objective of this study was to describe the prevalence and details of skin rash to diabetes MDs in adults with type 1 diabet

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We report three cases of contact allergy to a mislabelled hair dye product. A hair dye product labelled as p-phenylenediamine-free has been found to contain p-phenylenediamine by a chemical analysis at the level above the limits allowed in the product.