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Development of a multinational registry of pediatric deceased organ donation activity

There are no currently agreed upon international standards for reporting of pediatric deceased organ donation activity. This leads to difficulty in comparisons between jurisdictions for both researchers and policy stakeholders. The goal of this project was to develop and test a standardized registry for pediatric deceased donation activity. New publication in Pediatric Transplantation.Read more he

https://www.lupop.lu.se/article/development-multinational-registry-pediatric-deceased-organ-donation-activity - 2025-10-05

Commonly used estimates of the genetic contribution to disease are subject to the same fallacies as bad luck estimates

The scientific debate following the initial formulation of the “bad luck” hypothesis in cancer development highlighted how measures based on analysis of variance are inappropriately used for risk communication. The notion of “explained” variance is not only used to quantify randomness, but also to quantify genetic and environmental contribution to disease in heritability coefficients. New publicat

https://www.lupop.lu.se/article/commonly-used-estimates-genetic-contribution-disease-are-subject-same-fallacies-bad-luck-estimates - 2025-10-05

Whole-genome sequencing of triple-negative breast cancers in a population-based clinical study

Whole-genome sequencing (WGS) brings comprehensive insights to cancer genome interpretation. To explore the clinical value of WGS, we sequenced 254 triple-negative breast cancers (TNBCs) for which associated treatment and outcome data were collected between 2010 and 2015 via the population-based Sweden Cancerome Analysis Network–Breast (SCAN-B) project (ClinicalTrials.gov ID:NCT02306096). New publ

https://www.lupop.lu.se/article/whole-genome-sequencing-triple-negative-breast-cancers-population-based-clinical-study - 2025-10-05

Population-Based Observational Studies in Oncology: Proceed With Caution

A principle goal of research in Oncology is to determine the optimal treatment for our patients. This often takes the form of comparing 2 existing therapies to one another to determine which is superior, or to introduce a new therapy and determine if it is superior or noninferior to the existing standard of care. New publication in Seminars in Radiation Oncology

https://www.lupop.lu.se/article/population-based-observational-studies-oncology-proceed-caution - 2025-10-05

Validation of diagnosis codes to identify side of colon in an electronic health record registry

ICD codes are a highly reliable indicator of tumor location when the specific location code is entered in the EHR. However, non-specific side of colon ICD codes are present for a sizable minority of patients, and structured data alone may not be adequate to support testing of some research hypotheses. New publication in BMC Medical Research Methodology

https://www.lupop.lu.se/article/validation-diagnosis-codes-identify-side-colon-electronic-health-record-registry - 2025-10-05

Key concepts and principles for design and critical interpretation of Nordic register-based studies

This two-week course is divided into two separate course weeks. The course will be arranged as a retreat somewhere in Sweden. Travel costs and accommodation will be covered in relation to the educational activities. The target group is doctoral students (and those who have recently completed their doctoral education) involved in register-based research within their research training. Eligible appl

https://www.lupop.lu.se/article/key-concepts-and-principles-design-and-critical-interpretation-nordic-register-based-studies-0 - 2025-10-05

A critical reflection on the grading of the certainty of evidence in umbrella reviews

In conclusion, umbrella reviews provide a comprehensive overview of a specific research topic and are very helpful tools to evaluate the certainty of evidence. These systematic overviews are helpful for the translation of research findings into recommendations, and also for identifying new research directions. New publication in European Journal of Epidemiology

https://www.lupop.lu.se/article/critical-reflection-grading-certainty-evidence-umbrella-reviews - 2025-10-05

Chronic pain: a review of its epidemiology and associated factors in population-based studies

Chronic pain is a common, complex, and distressing problem that has a profound impact on individuals and society. It frequently presents as a result of a disease or an injury; however, it is not merely an accompanying symptom, but rather a separate condition in its own right, with its own medical definition and taxonomy. New publication in British Journal of Anaesthesia

https://www.lupop.lu.se/article/chronic-pain-review-its-epidemiology-and-associated-factors-population-based-studies - 2025-10-05

Doing more of less: what registry data tell us about death in PICU

The development of paediatric critical care registries, a term we take to include national audits and research databases, has been instrumental in helping us understand the state of children’s critical care and thereby provide a platform for future improvement. Comprehensive datasets enable monitoring of activity and outcomes for audit, safety and service planning. New publication in Intensive Car

https://www.lupop.lu.se/article/doing-more-less-what-registry-data-tell-us-about-death-picu - 2025-10-05

Twin Registries Moving Forward and Meeting the Future: A Review

Twin registries have developed as a valuable resource for the study of many aspects of disease and society over the years in many different countries. A number of these registries include large numbers of twins with data collected at varying information levels for twin cohorts over the past several decades. New publication in Cambridge Core

https://www.lupop.lu.se/article/twin-registries-moving-forward-and-meeting-future-review - 2025-10-05

Ny utlysning från Vetenskapsrådet

Detta bidrag syftar till att stödja internationella samarbeten inom det europeiska programmet CHIST-ERA, som stödjer forskning inom informations- och kommunikationsteknologi (IKT). Sverige är via Vetenskapsrådet ett av de 24 länder som deltar i CHIST-ERA-utlysningen där forskning av högsta vetenskapliga kvalitet i internationell konkurrens premieras. Vetenskapsrådet deltar i utlysningen inom ämne

https://www.lupop.lu.se/article/ny-utlysning-fran-vetenskapsradet - 2025-10-05

Nya utlysningar från Vetenskapsrådet

Följande utlysningar från Vetenskapsrådet är nu öppna. Bidrag för aktiviteter inom MINT-ämnen vid nationella forskningsinfrastrukturer (Söks av organisation)Tage Erlanders gästprofessur (Söks av organisation)Bidrag till forskningsmiljö inom klinisk behandlingsforskningKonsolideringsbidrag (Skissansökan)Internationell postdokKerstin Hesselgrens gästprofessur (Söks av organisation)Olof Palmes gästpr

https://www.lupop.lu.se/article/nya-utlysningar-fran-vetenskapsradet-0 - 2025-10-05

Nya utlysningar från VR

Följande utlysningar från Vetenskapsrådet är nu öppna Projektbidrag inom humaniora och samhällsvetenskap  Projektbidrag inom medicin och hälsaProjektbidrag för digitalisering och tillgängliggörande av kulturarvssamlingarProjektbidrag för utveckling av metoder för ersättning, begränsning och förfining av djurförsök (3R)Tidskriftsbidrag inom humaniora och samhällsvetenskap (Söks av organisation)Bidr

https://www.lupop.lu.se/article/nya-utlysningar-fran-vr - 2025-10-05

Spanish National Hip Fracture Registry (RNFC): analysis of its first annual report and international comparison with other established registries

Hip fracture registries have helped improve quality of care and reduce variability, and several audits exist worldwide. The results of the Spanish National Hip Fracture Registry are presented and compared with 13 other national registries, highlighting similarities and differences to define areas of improvement, particularly surgical delay and early mobilization. New publication in Osteoporosis In

https://www.lupop.lu.se/article/spanish-national-hip-fracture-registry-rnfc-analysis-its-first-annual-report-and-international - 2025-10-05

Registry stakeholders

Clinical registries are health information systems, which have the mission to collect multidimensional real-world data over the long term, and to generate relevant information and actionable knowledge to address current serious healthcare problems. New publication in Bone & Joint.Read more here.

https://www.lupop.lu.se/article/registry-stakeholders - 2025-10-05

The benefits of collaboration: the Nordic Arthroplasty Register Association

The Nordic Arthroplasty Register Association (NARA) was established in 2007 by arthroplasty register representatives from Sweden, Norway and Denmark with the overall aim to improve the quality of research and thereby enhance the possibility for quality improvement with arthroplasty surgery. Finland joined the NARA collaboration in 2010. New publication in Bone& Joint.Read more here.

https://www.lupop.lu.se/article/benefits-collaboration-nordic-arthroplasty-register-association - 2025-10-05