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Longitudinal changes in cardiovascular disease–related proteins in welders

Objective: Occupational exposure to welding fumes is linked to a higher risk of cardiovascular disease; however, the threshold exposure level is unknown. Here, we aimed to identify changes in proteins associated with cardiovascular disease in relation to exposure to welding fumes. Methods: Data were obtained from two timepoints six years apart for 338 non-smoking men (171 welders, 167 controls); o

Sustainability Transformation and the Transformative Capacity of Nation States: Implications of Innovation Policy

The need for radical transformations to respond to the environmental polycrises of climate change, biodiversity loss, and pollution has come to the forefront of political and academic debates. Nation states must have transformative capacity, meaning the ability to ignite, enable, and steer large-scale sustainability transformations. However, despite its importance, there remains a significant gap

Preoperatively suspected gallbladder cancer improves survival compared with incidental gallbladder cancer in pT3 patients

Background: The aim was to compare survival for incidental gallbladder cancer (IGBC), respectively, preoperatively suspected gallbladder cancer (GBC), subjected to surgery for different pathological tumour (pT) stages and in different treatment groups in a national cohort. Methods: Data were collected and crosslinked from two national quality registers, SweLiv (2009–2019) and GallRiks (2009–2016).

Vividness, narrative transportation, and sense of presence in destination marketing : empirical evidence from augmented reality tourism

The rise of augmented reality (AR) technology offers potential opportunities for the tourism industry and academia. Drawing upon narrative transportation and presence theory, this paper investigates the relationship between vividness, narrative transportation, sense of presence, and visiting other AR destination. The empirical findings indicate that vividness enhances narrative transportation and

A Statistical Framework for Assessing the Relationship between Biomarkers and Clinical Endpoints in Alzheimer’s Disease

Changes in biomarker levels of Alzheimer’s disease (AD) reflect underlying pathophysiological changes in the brain and can provide evidence of direct and downstream treatment effects linked to disease modification. Recent results from clinical trials of anti–amyloid β (Aβ) treatments have raised the question of how to best characterize the relationship between AD biomarkers and clinical endpoints.

Samhällsutveckling innebär nya förutsättningar för stora byggprojekt

Inte sällan beskrivs byggbranschen som konservativ och motvillig till förändringar, både av folk i branschen, av forskare samt av folk i allmänhet. Likväl har byggbranschen under årens lopp genomgått ett antal förändringar, ofta som reaktioner på nya förutsättningar skapade av förändringar i det omgivande samhället. Den här artikeln redovisar hur ett antal projektledare i stora byggprojekt uppfatt

The Socioeconomics of Wind Power Expansion: Evidence from Sweden

We document the socioeconomics of wind power expansion in Sweden using two metrics. First, we compute the difference in socioeconomic status (SES) between residents exposed to wind power (0-2 km from the closest turbine) and those not exposed. For each site, the metric is computed ten years prior until five years after construction. When the comparison group is other residents within the same muniWe document the socioeconomics of wind power expansion in Sweden using two metrics. First, we compute the difference in socioeconomic status (SES) between residents exposed to wind power (0-2 km from the closest turbine) and those not exposed. For each site, the metric is computed ten years prior until five years after construction. When the comparison group is other residents within the same muni

Photoinduced charge transfer renormalization in NiO

Photodoped states in strongly correlated charge-Transfer insulators are characterized by d-d and d-p interactions and the resulting intertwined dynamics of charge excitations and local multiplets. Here, we use femtosecond x-ray absorption spectroscopy in combination with dynamical mean-field theory to disentangle these contributions in NiO. Upon resonant optical excitation across the charge-Transf

Influence of Scanning Strategy on Residual Stresses in Laser-Based Powder Bed Fusion Manufactured Alloy 718 : Modeling and Experiments

In additive manufacturing, the presence of residual stresses in produced parts is a well-recognized phenomenon. These residual stresses not only elevate the risk of crack formation but also impose limitations on in-service performance. Moreover, it can distort printed parts if released, or in the worst case even cause a build to fail due to collision with the powder scraper. This study introduces

Traffic Safety Footprint in Sustainability Practices and Reporting—Exploring the Views of Companies

Road traffic accidents cause nearly 1.3 million deaths and around 50 million injuries each year globally. Most organisations generate travel and transport, and influence thereby traffic safety. In Sweden, 47 percent of fatal accidents in road traffic are work-related, and 36 percent are linked to a procured transport service. Effective approaches to managing traffic safety in organisations have no

Loop Dynamics and Enzyme Catalysis in Protein Tyrosine Phosphatases

Protein tyrosine phosphatases (PTPs) play an important role in cellular signaling and have been implicated in human cancers, diabetes, and obesity. Despite shared catalytic mechanisms and transition states for the chemical steps of catalysis, catalytic rates within the PTP family vary over several orders of magnitude. These rate differences have been implied to arise from differing conformational

From Funding to Financing: Complementary Pathways, Refugee Finance and the Emergence of the Refugee Entrepreneur

As part of the implementation of the Comprehensive Refugee Response Framework and the Global Compact on Refugees we are witnessing the promotion of refugee responses aimed at creating an enabling environment for sustainable investments. This marks a paradigmatic shift “from funding to financing” which sees the role of financial markets becoming central to the way in which refugee responses are man

Energy-resolved fast-neutron radiography using an event-mode neutron imaging detector

Energy-resolved fast-neutron radiography is a powerful non-destructive technique that can be used to remotely measure the quantity and distribution of elements and isotopes in a sample. This is done by comparing the energy-dependent neutron transmission of a sample with the known cross-sections of individual isotopes. The reconstruction of the composition is possible due to the unique features (e.

Competing or complementary? : Socio-technical imaginaries of a bio-based construction sector

The construction sector needs to transition toward using bio-based building materials in order to reduce its negative environmental impact. However, it is unclear how exactly such a bio-based future will look like, with different stakeholders in different geographical contexts having different visions of the sector’s future. Based on an extensive collection of expert interviews with stakeholders f

The Interplay Between Visual Traits and Forest in Bumblebee Communities Across Sweden

Understanding how ecological communities assemble in relation to natural and human-induced environmental changes is critical, particularly for communities of pollinators that deliver essential ecosystem services. Despite widespread attention to interactions between functional traits and community responses to environmental changes, the importance of sensory traits has received little attention. To

Pollination Across the Diel Cycle : A Global Meta-Analysis

The daily transition between day and night, known as the diel cycle, is characterised by significant shifts in environmental conditions and biological activity, both of which can affect crucial ecosystem functions like pollination. Despite over six decades of research into whether pollination varies between day and night, consensus remains elusive. We compiled the evidence of diel pollination from