Novel immunotherapeutic approach: winning at hide and seek Cancer always plays a constant hide and seek game with the immune system. Tumor cells have developed multiple mechanisms to evade the immune system, including dendritic cells (DCs). DCs are in charge of obtaining antigens from cancer cells and present them to other cells such as Natural Killer cells and T-cells, which in turn are capable

Pericytes play an important role in the integrity of blood brain barrier. They have intricate communication with several other cell types in the brain, both through paracrine and endocrine signaling. We have previously shown that in vitro-cultured pericytes secrete various cytokines, chemokines and microparticles in disease model-systems in vitro. However, the temporal dynamics and specificity of

Based on qualitative data, I explore notions of collective identities within Europe – in particular, whether and how the EU and Europe evoke a sense of belonging. The main data comprises 12 semi-structured interviews with Europeans living in two different border regions, Lampedusa and the Danish-German borderland, together with pro- and anti-European movements and communities. The interviews are c

NIF.CD2-GFP -ny musmodell för kronisk inflammation & fibros Bildandet av fibrös vävnad är kroppens normala respons då en skada uppstått. Läkeprocessen är vanligtvis strikt reglerad men kan vid upprepad kronisk skada övergå till en okontrollerad och obalanserad process i vilken kroppens egna vävnader byts ut mot ärrvävnad -fibros. För mycket ärrbildning kan i sin tur vara skadligt och leda tilFibrosis is a process characterized by the accumulation of extracellular matrix components and is attributed to excessive scar formation and is a common feature of many chronic inflammatory conditions. Fibrogenesis involves multiple inflammatory cells including NKT cells, which have been suggested to play a prominent role in the control of this process. Here we characterize a transgenic mouse mode

This thesis investigates historical narratives that were exhibited during a plenary session in the European parliament prior to accepting the resolution Importance of remembrance for the Future of Europe. The resolution states that the European parliament from here on and after will regard the Molotov-Ribbentrop pact as the direct cause of the Second World War. Trough narrative analysis, the thesi

Byggprocessen har en omfattande roll i det infrastrukturella bygget och utgör grunden till en byggnation. Man kan uttrycka byggprocessen som en helhetsbild av hur uppförandet av en byggnad/anläggning går till. Många olika aktörer är involverade i denna process. Byggprocessen innefattar allt från inventeringar, behovsutredningar, gestaltningar till tekniska lösningar, produktion och förvaltning. ÄvThe construction process has a profound role withing the infrastructure, and lais the foundation for the construction itself. It can be described as layout of how the construction will be managed, provided for and organized. Therefore, this process involves several actors. The construction process involves activities such as inventory, needs investigations, designs for technical solutions, product

It has become more important for people worldwide to eat and drink products that offer us health- promoting benefits, which traditional foods do not possess. These kinds of products are called functional foods and have been fortified using vitamins, minerals or probiotics among others. Today, there are a lot of probiotic strains on the market and the first part of the aim of this study was to eval

Trafikverket upphandlar funktionsentreprenader för att öka attraktiviteten hos anläggningsbranschen. I denna upphandlingsform har Trafikverket omvandlat tekniska lösningar till funktionskrav, som i sin tur tillåter entreprenören att komma på egna tekniska lösningar. Trafikverket som beställare behöver veta kvalitén på vägen som levereras i slutet av garantitiden. Kvalitén kan undersökas genom blThe Swedish Transport Administration procures performance contracts to increase the attractiveness of the construction industry. In this procurement, The Swedish Transport Administration has transformed technical solutions into functional requirements. This allows the contractor to develop his own technical solutions. As a customer, The Swedish Transport Administration needs to find out the quali

Syftet med denna avhandling är att undersöka hur respondenterna från fem strukturerade intervjuer och har förändrat sin syn på konsumentbeteende, som ett resultat av utvecklingen av e-handel, med fokus på detaljhandel och konsumenthandel. Avhandlingen undersöker hur och om den förändrade synen har påverkat e-handeln med kläder och skor. Utöver de fem strukturerade intervjuerna har sekundära källoThe purpose of this thesis is to investigate how the respondents from five structured interviews and have changed their view of the consumer behavior, as a result of the development of e-commerce, with a focus on retail and consumer shopping. The thesis examine how and if the changed view has affected e-commerce in clothing and shoes. In addition to the five structured interviews secondary source

Ett av vetenskapens största mål är att få rena och skalbara energikällor. Om detta ska ha en positiv effekt på klimatförändringar måste det utföras effektivt och förhoppningsvis så fort så möjligt. Flera övergångsmetallkomplexer, exempelvis andra- och tredje raden övergångsmetaller har tidigare framgångsrikt använts för ändamål såsom fotokatalys och andra artificiella ljusskördesystem. Dessa övergThe structural properties in the ground and the excited states of the hexa-coordinated iron carbene molecule FeIII(phtmeimb)2PF6 were investigated by ultrafast time-resolved X-ray absorption spectroscopy (XAS)techniques. Namely X-ray absorption near edge structure (XANES) and Extended X-ray Absorption FineStructure (EXAFS). Data from a time-resolved pump-probe synchrotron radiation experiment was

Syftet med detta kandidat arbete var att utveckla ett instrument for att mäta resistansen av olika metaller utan tråd kopplingar mellan metall provet och voltmetern. Detta kan uppnås med magnetfält och en metod som kallas Bean, uppkallad efter C.P. Bean som, med hjälp av samarbetare, först utveckla metoden 1959. Arbetet börja med att konstrurera en rigg till framställningen av spolarna, följt av The aim of this thesis work was to develop a rig to measure the resistivity of a metal sample. The initial testing of the rig would be done at room temperature and calibration of the setup would be done with aluminum samples and then metallic alloys would be studied. The method implemented is a contactless one where the diffusion of eddy currents in a sample is measured by a coil and the resistivi

The purpose is to explore the phenomenon of authentic brands extending into other categories in order to identify how this may affect the image of the brand and its authenticity.

Potential use of circulating tumor DNA as a biomarker in children’s cancer Pediatric cancer is the second most common cause of death in children in the developed countries, even though a highly improvement in diagnostic tools and treatment strategies occurred in the last decade. Cancer patients have to endure long treatments with many side effects, with possible multiple surgeries, and radiation.

Purpose – This paper aims to improve the understanding how entrepreneurs practice inexpensive marketing by utilising human and social capital instead of financial resources. Methodology – This study was conducted following a qualitative methodology. The data was collected in seven semi-structured interviews with entrepreneurs who have made use of inexpensive marketing concepts and methods. We ana

This study analyzes the impact that the upcoming Basel III regulations will have on the equity related capital charge faced by banks with respect to their equity portfolio holdings. Two research objectives underpin this research; the first one relates to the effective impact that a switch from VaR0.99 to ES0.975 might have for the capital charge related to market risk of three representative equit

The aim of this bachelor thesis is to study and investigate why students at Lund University dresses the way they do and how their clothes communicates and give others a glimpse of who they are. The title of the paper What should I wear – A study about how students in Lund communicate through their clothes gives the reader an insight into what the essay will focus on. To answer these questions the

Quadratic voting has been proposed as a voting procedure that aggregates preferences in a near-utilitarian way. A voter’s optimal strategy is, however, not solely a function of her preferences, but also of her beliefs about how others will vote. This thesis presents a formal model of quadratic voting that, unlike previous models, allows for heterogeneity in the beliefs of voters. The specification

Informed by anti-carceral feminism and theories as well as practices of transformative justice (TJ) and community accountability (CA), this thesis critically investigates court trials in Denmark and calls for further thinking and action in handling harm beyond carcerality. Through observing 11 rape trials, I outline the logics of processing conflicts within the court system, focusing on how they c

This thesis uses Feminist Critical Discourse Analysis and Multimodal Discourse Analysis to study how a house of brands, like Procter & Gamble (P&G), handles femvertising, that it is produced by its own brands. The paper analyses the phenomenon using examples from commercials that belong to P&G’s #WeSeeEqual campaign and the controversial commercial video from Gillette The best men can

Papillomavirus, the leading cause of cervical cancer Papillomaviruses are family of viruses that infect mammals and their uncured infection can lead to cancer. In humans, they can cause as much as 5% of all the cancers worldwide. Even though some papillomavirus types can also cause warts on hands and feet that will clear on its own, some types, regarded as high-risk by specialists, can infect the