A Guide to Choose the Most Suited Superdisintegrant - General considerations and watchout when optimizing ODT-formulations
The inclusion of a superdisintegrant in an ODT-formulation is necessary to ensure that its disintegration behaviour is on point. However, given the wide array of circumstances that might influence this conduct, it is still very difficult to predict the complete disintegration behaviour of an ODT-formulation. Examples of such circumstances are excipient and API-interaction. In order to reduce these