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Worse self-reported outcomes but no limitations in performance-based measures in patients with long-standing hip and groin pain compared with healthy controls

PURPOSE: This study aimed to evaluate patient-reported outcomes as well as lower extremity and trunk muscle function in patients with long-standing hip and groin pain, in comparison with matched, healthy controls. It was hypothesized that patients with long-standing hip and groin pain would report more deficiency on the Copenhagen Hip and Groin Outcome Score (HAGOS) and have worse outcomes on perf

Reslizumab for Inadequately Controlled Asthma with Elevated Blood Eosinophil Levels : a Randomized Phase 3 Study

BACKGROUND: This phase 3 study further characterizes the efficacy and safety of reslizumab (a humanized anti-interleukin-5 monoclonal antibody) in patients aged 12-75 years with asthma inadequately controlled by at least a medium-dose inhaled corticosteroid, and blood eosinophils ≥400cells/μL.METHODS: Patients were randomized to receive reslizumab 0.3 or 3.0mg/kg or placebo once/every 4 weeks/16 w

Territory occupancy and parental quality as proxies for spatial prioritization of conservation areas

In order to maximize their fitness, individuals aim at choosing territories offering the most appropriate combination of resources. As population size fluctuates in time, the frequency of breeding territory occupancy reflects territory quality. We investigated the relationships between the frequency of territory occupancy (2002-2009) vs. habitat characteristics, prey abundance, reproductive succes

With a little help from my friends : relational work in leisure-related enterprising

The present article analyses the indistinct boundaries between formal and informal economic exchanges, with a focus on friendship and work relations. To illustrate these intersections, we present a study of Swedish lifestyle entrepreneurs who run small-scale horse-related enterprises. The specific characteristics of this form of business—in which the horse farm owners/operators, customers, employe

High effectiveness of tailored flower strips in reducing pests and crop plant damage

Providing key resources to animals may enhance both their biodiversity and the ecosystem services they provide. We examined the performance of annual flower strips targeted at the promotion of natural pest control in winter wheat. Flower strips were experimentally sown along 10 winter wheat fields across a gradient of landscape complexity (i.e. proportion noncrop area within 750 m around focal fie

Perennial, species-rich wildflower strips enhance pest control and crop yield

The effectiveness of agri-environment schemes (AES) such as wildflower strips in promoting farmland biodiversity has been relatively well studied. Their effects on biodiversity-mediated ecosystem services, such as natural pest control, in contrast, remain poorly evaluated and their consequences on crop yield largely unexplored. We assessed the effect of sown, species-rich, perennial wildflower str

Particle shape effects in colloidal crystals and colloidal liquid crystals: Small-angle X-ray scattering studies with microradian resolution

Small-angle X-ray scattering (SAXS) is an indispensable tool in structural investigations of self-assembled colloidal crystals and colloidal liquid crystals. This paper reviews recent studies of the particle shape effects on the crystal structure as revealed by SAXS. Rod-like, plate-like, biaxial board-like as well as cubic-like shapes are discussed. Since relatively large, (sub)micron particles a

Tailored flower strips promote natural enemy biodiversity and enhance pest control in adjacent potato crops

Sown flower strips are increasingly implemented within agri-environment schemes (AES) to increase functional biodiversity and ecosystem services such as pollination or natural pest control, but their effectiveness in achieving these goals remains poorly studied. We tested the performance of experimentally sown annual flower strips specifically designed to promote natural enemies of aphids and thei

Targeted flower strips effectively promote natural enemies of aphids

Sown wildflower strips are increasingly established within agri-environmental schemes in Europe and worldwide. Their goals include the promotion of biodiversity, pest control or pollination services. Here, we tested whether a new type of flower strip targeted to promote natural enemies controlling aphids and other wheat pests are more effective in achieving this goal than an already implemented wi

Stress-induced ST elevation with or without concomitant ST depression is predictive of presence, location and amount of myocardial ischemia assessed by myocardial perfusion SPECT, whereas isolated stress-induced ST depression is not

BACKGROUND: Evaluation of stress-induced ST deviations constitutes a central part when interpreting the findings from an exercise test. The aim of this analysis was to assess the pathophysiologic correlate of stress-induced ST elevation and ST depression with regard to presence, amount and location of myocardial ischemia as assessed by myocardial perfusion SPECT (MPS) in patients with suspected co

Proinflammatory Role of Sphingolipids and Glycosphingolipids in the Human Atherosclerotic Plaque

OBJECTIVE: Lipids are central to the development of atherosclerotic plaques. Specifically, which lipids are culprits remains controversial, and promising targets have failed in clinical studies. Sphingolipids are bioactive lipids present in atherosclerotic plaques, and they have been suggested to have both proatherogenic and antiatherogenic. However, the biological effects of these lipids remain u

Characteristics of adolescents with poor mental health after bariatric surgery

BACKGROUND: About 20% of adolescents experience substantial mental health problems after bariatric surgery.OBJECTIVES: The aim of this study was to explore differences between adolescents with poor mental health (PMH) 2 years after surgery and those with average/good mental health.SETTING: Three university hospitals in Sweden.METHODS: Mental health and health-related quality of life were assessed

Breath-holding spells occur disproportionately more often in children with transient erythroblastopenia

AIM: This study aimed to evaluate the concomitant occurrence and possible association of breath-holding spells (BHS) and transient erythroblastopenia of childhood (TEC).METHODS: This population-based cohort study, carried out in Southern Sweden from 2004-2014, included patients with BHS and, or, anaemia, including TEC. The subjects were evaluated for the presence of all three conditions and the di

'They are totally unfiltered' : Constructions of the child audience among Swedish advertising producers

This article analyzes how producers of advertising construct children as an advertising audience. Previous research has argued that marketers are bound to present children as competent and savvy to legitimize their own practices. Drawing on interviews with Swedish producers of child-directed online advertising, this study shows that marketers are not destined to portray children as competent as th

High risks of maternal and perinatal complications in singletons born after oocyte donation

INTRODUCTION: Previous studies have shown an increased risk of obstetric complications in pregnancies after oocyte donation (OD). The present study includes all singletons born after OD during 10 years in Sweden.MATERIAL AND METHODS: A retrospective cohort study that included data from all Swedish in vitro fertilization (IVF) clinics between 2003 and 2012 was performed. Data were cross-linked with

Immunomodulation - a disease-modifying avenue for treatment of Huntington's disease?

This Editorial highlights a study published in the current issue of Journal of Neurochemistry by Dobson et al. (), investigating whether the immunomodulatory agent, laquinimod exerts an immunomodulatory effect on isolated Huntington´s disease monocytes. In Huntington´s disease (HD) a central immune activation is mirrored in the periphery by a low-grade immune response and monocytes isolated from H

A prospective evaluation of early detection biomarkers for ovarian cancer in the European EPIC cohort

PURPOSE: About 60% of ovarian cancers are diagnosed at late stage, when 5-year survival is less than 30% in contrast to 90% for local disease. This has prompted search for early detection biomarkers. For initial testing, specimens taken months or years before ovarian cancer diagnosis are the best source of information to evaluate early detection biomarkers. Here we evaluate the most promising ovar

Mn enriched surface of annealed (GaMn)As layers annealed under arsenic capping

Using synchrotron radiation based spectroscopic methods we have investigated the surface modifications of Ga1-x Mnx As layers due to post growth annealing under amorphous arsenic capping layers. It is established that there is a clear increase of the Mn concentration at the surface after annealing. This is ascribed to a reaction between diffusing Mn interstitials and the As capping. The reacted su