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Legal and Lethal : Lawfare and Legal Mobilization in the Conflict over the Steel Plant of Taranto, Italy

Denna studie undersöker konflikten i Taranto, en stad i södra Italien som sedan 1960 talet har hyst ett av Europas största stålverk, Ilva. Under årtiondenas lopp har Ilva omformat Tarantos socioekonomiska och miljömässiga landskap och orsakat allvarlig förorening, som epidemiologiska studier har kopplat till överdödlighet och ökad sjuklighet. Denna kris har lett till en konflikt som också har utkäThis study examines the conflict in Taranto, a city in Southern Italy that has hosted one of Europe’s largest steel plants, Ilva, since the 1960s. Over the decades, Ilva has reshaped Taranto’s socioeconomic and environmental landscape, causing severe pollution that epidemiological studies have linked to excess mortality and morbidity. This crisis has led to a conflict fought also through legal mea

Contribution of rare variation to degenerative orthopedic diseases

Objective: Degenerative orthopedic diseases (DODs) such as osteoporosis, osteoarthritis, spondylosis, spinal stenosis, and disc herniation are common disorders. Both common and rare genetic risk factors may contribute to DODs, but few large-scale whole-exome sequencing studies elucidating the contribution of rare variations to DODs have been published. The updated version of the Astra Zeneca porta

Non-Fickian diffusion within assemblies of the intrinsically disordered protein β-casein

The molecular mechanisms governing internal fluctuations in intrinsically disordered protein (IDP) assemblies are crucial to the stability and dynamics of both regulated and aberrant toxic cellular aggregates, but remain poorly understood. By comprehensively combining high-resolution quasi-elastic neutron scattering with all-atom molecular dynamics simulations, we probe the motions of β-casein, a

Stora ojämlikheter i hur svenska barn växer upp : Tre forskare om barnfattigdomen i Sverige

DEBATT. I tider av hög arbetslöshet och ökade matpriser riskerar många familjer att drabbas av ekonomisk utsatthet. Men barnfattigdomen i Sverige är kraftigt ojämnt fördelad. Vår ESO-rapport visar att risken att växa upp i fattigdom varierar med föräldrarnas arbetsmarknadsanknytning, familjens storlek och om barnet lever med en ensamstående förälder. Skillnaderna är stora mellan barn till utrikesf

CryoFluorSEM – A new approach for fluorescence and EM imaging of cryofractured plant samples

Cryo-scanning electron microscopy (CryoSEM) permits the preparation and detailed imaging of bulky samples while keeping them in a hydrated state. For plant biology, cryofractures give information on cell ultrastructure and tissue organisation within a much larger context that is the whole organ or organism. To date, a method to locate fluorescence reporters on the cryofracture has not been reporte

Construction robot prototype : "Bettan"

Construction robot prototype for onsite work. Consists of an ABB IRB4600 mounted on a spindle crane chassi for mobility. Housed in a container for weather protection and logistics.

Interactions between genetic predisposition to obesity, insulin resistance and type 2 diabetes risk, and food or beverage intake for incident type 2 diabetes : European Prospective Investigation into Cancer and Nutrition (EPIC) InterAct case–cohort study

Background: Limited evidence exists for effect modification of genetic characteristics on the associations of food consumption and incident type 2 diabetes (T2D). Objectives: We aimed to investigate whether the food-T2D association would vary by genetic susceptibility to metabolic traits. Methods: We analyzed data from 9542 incident T2D cases and a subcohort of 12,477 participants nested within th

Between Admiration and Resistance: Postcolonial Legacies and Indonesian Public Perceptions of the European Union

Relations between the European Union (EU) and Indonesia have expanded significantly in recent decades, yet public perceptions of the EU in Indonesia are shaped not only by contemporary policies but also by enduring postcolonial legacies. In postcolonial societies, global actors are often interpreted through historically grounded narratives that influence how authority, legitimacy, and partnership

Factors affecting reproduction of Snow Leopards (Panthera uncia) in captivity: age, experience, and contraception

As snow leopards (Panthera uncia) are vulnerable in the wild, individuals in captivity function as a backup for the wild population. However, space limitations make it difficult to keep the captive population healthy. To maintain high genetic diversity in the captive population, it is important to carefully consider breeding recommendations and the use of contraception. This study examined age-rel

Identification and functional characterization of novel genes involved in the Cellulase-Induced Resistance to Alamethicin (CIRA) pathway in Arabidopsis thaliana

Trichoderma are fungi that form symbiotic relationships with plant roots, representing an ecological topic for pest management. It offers a sustainable alternative to agrochemicals through biostimulation and biocontrol. However, the host plant needs to effectively manage a trade-off : using Trichoderma as a defense mechanism while not getting damaged by its cytotoxic compounds, like the antibiotic

Nästa generation av tumörbehandling? : Kap. IV. Pre-Kirurgisk Intermittent Strålbehandling och immunoadjuvant hypertermi

Sammanfattning av Kapitel IV:Detta kapitel handlar om att kombinera Pre-kirurgisk strålbehandling och hypertermi (värmebehandling) med fokus på immunologiska effekter. Hypertermi (HT ca 41–44 °C) gör tumörceller mer känsliga för strålning (RT). Kliniska studier visar bättre respons och fler kompletta remissioner med kombinationen RT+HT jämfört med enbart strålning (RT) utan att öka allvarliga bive

Early glymphatic failure in AppNL-F knock-in mice is linked to parenchymal border macrophages loss

Amyloid-β (Aβ) accumulation is a hallmark of Alzheimer’s disease. Cerebral Aβ deposition is attenuated by a functional glymphatic system, in which perivascular entry of cerebrospinal fluid (CSF) and its exchange with interstitial fluid mediate solute clearance. Parenchymal border macrophages (PBMs), positioned along glymphatic pathways, are emerging as important players for glymphatic clearance. H