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Inhibitor development: patient-determined risk factors.

Summary. The reasons that inhibitory factor VIII antibodies develop in only a fraction of patients with haemophilia A remain unclear, but studies of genetically related subjects have indicated that the immunological outcome of replacement therapy is to a large extent determined by patient-related risk factors. Non-genetic factors will also influence the inhibitor risk, since events challenging the

C-reactive protein, metabolic syndrome and incidence of severe hip and knee osteoarthritis. A population-based cohort study.

OBJECTIVE: To explore the relationships between C-reactive protein (CRP), metabolic syndrome (MetS) and incidence of severe knee or hip osteoarthritis (OA) in a prospective study. METHODS: A population-based cohort (n=5171, mean age 57.5+/-5.9 years) was examined between 1991 and 1994. Data was collected on lifestyle habits, measures of overweight, blood pressure as well as high-density lipoprotei

To what extent can linear finite element Models of Human femora predict failure under stance and fall loading configurations?

Proximal femur strength estimates from Computed Tomography (CT)-based Finite Element (FE) models are finding clinical application. Published models reached a high in-vitro accuracy, yet many of them rely on nonlinear methodologies or internal best-fitting of parameters. The aim of the present study is to verify to what extent a linear FE modelling procedure, fully based on independently determined

A novel method for online analysis of gas and particle composition: description and evaluation of a Filter Inlet for Gases and AEROsols (FIGAERO)

We describe a novel inlet that allows measurement of both gas and particle molecular composition when coupled to mass spectrometric, chromatographic, or optical sensors: the Filter Inlet for Gases and AEROsols (FIGAERO). The design goals for the FIGAERO are to allow unperturbed observation of ambient air while simultaneously analyzing gases and collecting particulate matter on a Teflon® (hereafter

Knee rotation in healthy individuals related to age and gender.

An external device ("the Rottometer") was especially designed to measure passive knee rotation in vivo. The device had earlier been evaluated with respect to it's validity and reliability. In the present study, we evaluated knee rotation in knee-healthy individuals and studied possible age and gender related differences. Measurements of total internal-external rotation were made at 90°, 60°, and 3

Handling discourse: Gestures, reference tracking, and communication strategies in early L2

The production of cohesive discourse, especially maintained reference, poses problems for early second language (L2) speakers. This paper considers a communicative account of overexplicit L2 discourse by focusing on the interdependence between spoken and gestural cohesion, the latter being expressed by anchoring of referents in gesture space. Specifically, this study investigates whether overexpli

Lifelong prophylaxis in a large cohort of adult patients with severe haemophilia: a beneficial effect on orthopaedic outcome and quality of life.

Background: In the 1950s, Sweden initiated prophylaxis as a lifelong treatment for haemophilia. It was the first country to do so. Objective: To describe and evaluate dosing and outcome of prophylactic treatment in a large cohort of adult people with severe haemophilia who have been using prophylaxis most of their lives. Methods: Eighty-one patients born between 1932 and1992 were divided into two

Ethanol-Diesel Fumigation in a Multi-Cylinder Engine

Fumigation was studied in a 12 L six-cylinder heavy-duty engine. Port-injected ethanol was ignited with a small amount of diesel injected into the cylinder. The setup left much freedom for influencing the combustion process, and the aim of this study was to find operation modes that result in a combustion resembling that of a homogeneous charge compression ignition (HCCI) engine with high efficien

Integrating Mobility Prediction and Resource Pre-Allocation into a Home- Proxy Based Wireless Internet Framework

Browse Conference Publications > Networks, 2000. (ICON 2000). ... Help Integrating mobility prediction and resource pre-allocation into a home-proxy based wireless Internet framework This paper appears in: Networks, 2000. (ICON 2000). Proceedings. IEEE International Conference on Date of Conference: 2000 Author(s): Chan, J. Sch. of Electr. Eng. & Telecommun., New South Wales Univ., Kensingto

SEEDING OF THE TEST-FEL AT MAX-LAB

The installation of the test FEL at MAX-lab has recently been completed. The system will be seeded by a tripled Ti:Sapphire laser (263 nm) synchronized to the RF system and the gun laser. Issues important for the seeding will be presented, ranging from the laser system via the layout of photon and electron optics to timing/synchronization and the theoretical approach.

Lightweight Machine Learning for Seizure Detection on Wearable Devices

For patients with epilepsy, automatic epilepsy monitoring, i.e., the process of direct observation of the patient’s health status in real time, is crucial. Wearable systems provide the possibility of real-time epilepsy monitoring and alerting caregivers upon the occurrence of a seizure. In the context of the ICASSP 2023 Seizure Detection Challenge, we pro- pose a lightweight machine-learning frame