Sökresultat

Filtyp

Din sökning på "*" gav 529543 sökträffar

Hinode/EIS Measurements of Active-region Magnetic Fields

The present work illustrates the potential of a new diagnostic technique that allows the measurement of the coronal magnetic field strength in solar active regions by utilizing a handful of bright Fe x and Fe xi lines commonly observed by the high-resolution Hinode/EUV Imaging Spectrometer (EIS). The importance of this new diagnostic technique is twofold: (1) the coronal magnetic field is probably

NKT cells promote both type 1 and type 2 inflammatory responses in a mouse model of liver fibrosis

Sterile liver inflammation and fibrosis are associated with many liver disorders of different etiologies. Both type 1 and type 2 inflammatory responses have been reported to contribute to liver pathology. However, the mechanisms controlling the balance between these responses are largely unknown. Natural killer T (NKT) cells can be activated to rapidly secrete cytokines and chemokines associated w

Search for Higgs boson decays into two new low-mass spin-0 particles in the 4b channel with the ATLAS detector using pp collisions at s =13 TeV

This paper describes a search for beyond the Standard Model decays of the Higgs boson into a pair of new spin-0 particles subsequently decaying into b-quark pairs, H→aa→(bb¯)(bb¯), using proton-proton collision data collected by the ATLAS detector at the Large Hadron Collider at center-of-mass energy s=13 TeV. This search focuses on the range 15 GeV≤ma≤30 GeV, where the decay products are collimat

A century of Hereditas : from local publication to international journal

Background: The Mendelian Society of Lund launched Hereditas in 1920. The purpose of this article is to give an overview of Hereditas’s hundred-year existence, focusing on the conditions for a learned society to publish a scientific journal, and the journal’s importance for the publication and dissemination of genetic research. The article focuses on the historical development of the journal and a

On the cosmic origin of fluorine

The cosmic origin of fluorine, the ninth element of the periodic table, is still under debate. The reason for this fact is the large difficulties in observing stellar diagnostic lines, which can be used for the determination of the fluorine abundance in stars. Here we discuss some recent work on the chemical evolution of fluorine in the Milky Way and discuss the main contributors to the cosmic bud

Transcriptome profiling revealed early vascular smooth muscle cell gene activation following focal ischemic stroke in female rats – comparisons with males

Background: Women account for 60% of all stroke deaths and are more often permanently disabled than men, despite their higher observed stroke incidence. Considering the clinical population affected by stroke, an obvious drawback is that many pre-clinical and clinical studies only investigate young males. To improve therapeutic translation from bench to bedside, we believe that it is advantageous t

Socio-economic condition and lack of virological suppression among adults and adolescents receiving antiretroviral therapy in Ethiopia

Introduction The potential impact of socio-economic condition on virological suppression during antiretroviral treatment (ART) in sub-Saharan Africa is largely unknown. In this case-control study, we compared socio-economic factors among Ethiopian ART recipients with lack of virological suppression to those with undetectable viral load (VL). Methods Cases (VL>1000 copies/ml) and controls (VL6 mont

No title

From 1905 to 1940, 4% of all children and young people placed under Danish child welfare were discharged because they were perceived to be unresponsive to upbringing and care. Gradually a new concept was developed to describe the reason for their failure to transition to well-behaved children: “incorrigibility”. Based on the rise and use of this concept, this article examines the relationship betw

En biografi om en bok : Codex Upsaliensis B 68 från 1430

En biografi om en bok: Codex Upsaliensis B 68 från 1430 är en bokhistorisk studie om en medeltida handskrift och dess levnadshistoria, från tillblivelsen till mitten av 1700-talet. Handskriften är en illustrerad medeltida avskrift av Magnus Erikssons landslag men den är också och ett vittne från de tidsperioder som boken varit i omlopp. Antologin har som bakgrund ett seminarium som hölls 2017 på U

Outsourcing Empathy

Reflections on the impact of Covid-19 and the subsequent state measures on migrant workers.

Stochastic model for COVID-19 in slums: interaction between biology and public policies

We present a mathematical model for the simulation of the development of an outbreak of COVID-19 in a slum area under different interventions. Instead of representing interventions as modulations of the parameters of a free running epidemic we introduce a model structure that accounts for the actions but does not assume the results. The disease is modelled in terms of the progression of viremia re

Rapid neural processing of grammatical tone in second language learners

The present dissertation investigates how beginner learners process grammatical tone in a second language and whether their processing is influenced by phonological transfer. Paper I focuses on the acquisition of Swedish grammatical tone by beginner learners from a non-tonal language, German. Results show that non-tonal beginner learners do not process the grammatical regularities of the tones but

The societal costs of problem gambling in Sweden

Background: Problem gambling is a public health issue affecting both the gamblers, their families, their employers, and society as a whole. Recent law changes in Sweden oblige local and regional health authorities to invest more in prevention and treatment of problem gambling. The economic consequences of gambling, and thereby the potential economic consequences of policy changes in the area, are

Tumour-infiltrating lymphocytes as a prognostic and tamoxifen predictive marker in premenopausal breast cancer : data from a randomised trial with long-term follow-up

Background: Tumour-infiltrating lymphocytes (TILs) are of important prognostic and predictive value in human epidermal growth factor receptor 2-positive (HER2+) breast cancer (BC) and triple-negative breast cancer (TNBC), but their clinical relevance in oestrogen receptor-positive/HER2-negative (ER+/HER2−) remains unknown. The primary study aim was to analyse the prognostic effect of TILs on the B

Associations of self-reported atopic dermatitis with comorbid conditions in adults : a population-based cross-sectional study

Background: The objective of this study was to investigate the relationships between atopic dermatitis (AD) and other common chronic health conditions in adults. Methods: A cross-sectional survey was sent to a randomly selected population sample of 78,004 adults in Sweden. The questionnaires included measures of self-reported physical and mental health. Binary and multinomial logistic regression w

Calculation of hole concentrations in Zn doped GaAs nanowires

We have previously demonstrated that we can grow p-type GaAs nanowires using Zn doping during gold catalyzed growth with aerotaxy. In this investigation, we show how to calculate the hole concentrations in such nanowires. We base the calculations on the Zhang–Northrup defect formation energy. Using density functional theory, we calculate the energy of the defect, a Zn atom on a Ga site, using a su

Combined lentiviral- and RNA-mediated CRISPR/Cas9 delivery for efficient and traceable gene editing in human hematopoietic stem and progenitor cells

The CRISPR/Cas9 system is a versatile tool for functional genomics and forward genetic screens in mammalian cells. However, it has been challenging to deliver the CRISPR components to sensitive cell types, such as primary human hematopoietic stem and progenitor cells (HSPCs), partly due to lentiviral transduction of Cas9 being extremely inefficient in these cells. Here, to overcome these hurdles,

The reversal of human phylogeny : Homo left Africa as erectus, came back as sapiens sapiens

Background: The molecular out of Africa hypothesis, OOAH, has been considered as an established fact amid population geneticists for some 25–30 years despite the early concern with it among phylogeneticists with experience beyond that of Homo. The palaeontological support for the hypothesis is also questionable, a circumstance that in the light of expanding Eurasian palaeontological knowledge has