The exact physiological role for the monoamine serotonin (5-HT) in modulation of insulin secretion is yet to be fully understood. Although the presence of this monoamine in islets of Langerhans is well established, it is only with recent advances that the complex signaling network in islets involving 5-HT is being unraveled. With more than fourteen different 5-HT receptors expressed in human islet

BACKGROUND: Hyperthyroidism is associated with alterations in metabolism that are currently only partially understood. The objective of the study was to investigate changes in metabolism associated with reinstatement of euthyroidism in Swedish patients.METHODS: Eighty metabolites in plasma were profiled from 10 subjects with Graves' disease (GD) at baseline and after 9 and 15 months of treatment t

Feedback control is increasingly being applied in server systems to make them more robust and efficient. This includes managing quality of service, minimizing power consumption, and adapting to varying workloads. Successful adaptation and control in turn relies on accurate tracking of workload variations and timely detection of changes in the computing infrastructure. Given that server systems are

Elemental Carbon (EC) has been in focus for a long time due to its importance for climate effects and human health (WHO / IPCC). The pollutant is released by incomplete combustion of carbon fuels, making road traffic, off-road machinery, and wood stove burning the largest sources of EC emissions. In this work, we investigate the distribution of EC over Denmark using a combination of three models w

The term Bildung did not exist in the Reformation era. Rather, one spoke of "the Learned World." Coming up in the Renaissance, the Reformation was influenced by humanism and its prominent figures Johann Reuchlin and Erasmus of Rotterdam and their interest in the classical heritage with Latin as the scholarly lingua franca. Both Luther and Melanchthon attached themselves directly to that tradition

The article shows how Luther understood music as permeating everything in Creation, as God's gift, as donum, and as an invitation to praise and participation. For him, music and the love of Christ is expressed as loving embrace, inviting mutuality, participation, permeating life, in ways close to mysticism.

Inviterad inledning till paneldiskussion

We prove several off-diagonal and pointwise estimates for singular integral operators that extend compactly on Lp.(ℝn).

The chapter explores conceptions during the early twentieth century regarding the required and desired underpinnings of a post-imperial India – one in which both British India and the indirectly ruled princely states were first, by the British, proposed and then, through the work of the Indian Constituent Assembly, made to constitute a federation. It specifically enquires into India’s federal orig

I Lunds universitets handlingsplan för utveckling av e-lärande vid Lunds universitet 2016-18 beskrivs det som ett universitetsgemensamt mål att ”verka för en ökad användning av e-lärandeoch digitalt stöd för undervisning och examination [...]”.Under våren 2016 tillsattes en arbetsgrupp1 vid Lunds universitets bibliotek som hade tilluppgift att bland annat inventera bibliotekens arbete i digitala l

PURPOSE: To evaluate the digital KM screen computerized ocular motility test and to compare it with conventional nondigital techniques using the Hess and Lees screens.METHODS: Patients with known ocular deviations and a visual acuity of at least 20/100 underwent testing using the digital KM screen and the Hess and Lees screen tests. The examination duration, the subjectively perceived difficulty,

BackgroundActivated microglia play an essential role in inflammatory responses elicited in the central nervous system (CNS). Microglia-derived extracellular vesicles (EVs) are suggested to be involved in propagation of inflammatory signals and in the modulation of cell-to-cell communication. However, there is a lack of knowledge on the regulation of EVs and how this in turn facilitates the communi