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In the fields of behavioural and psychological research, pupil size and skin conductance are two variables that provide useful information about a participant’s state of mind at a given moment. Both variables are involuntary indicators of psychophysiological responses such as alertness, arousal, or focus. Pupil size is commonly measured with a video-based eye tracker, and skin conductance is measu
The RURITAGE Role Models represent thirteen tremendously diverse rural areas across Europe and beyond. By working on the 6 identified Systemic Innovation Areas (SIAs) – Pilgrimage, Local Food, Migration, Art&Festival, Resilience, Landscape – Role Models (RMs) have been selected as good practices in heritage-led rural regeneration and have been studied in WP1 to extract the so called ‘Role Mode
BACKGROUND: Arsenic methylation efficiency, a susceptibility factor for arsenic toxicity, is in adults partly explained by variation in arsenite methyltransferase (AS3MT) gene. Little is known about the role of AS3MT for children's arsenic methylation.OBJECTIVES: Evaluating associations between AS3MT polymorphisms and children's arsenic methylation efficiency.METHODS: Bangladeshi children's arseni
Dinoflagellates are a group of protists whose genome is unique among eukaryotes in terms of base composition, chromosomal structure and gene expression. Even after decades of research, the structure and behavior of their amazing chromosomes—which without nucleosomes exist in a liquid crystalline state—are still poorly understood. We used fl
Many-body effects in metals due to a change in the core electron occupation number appear in a large number of spectroscopies. The possible importance of the core hole has been realized and discussed for a very long time. Mahan's idea of excitons in metals gave the topic strong stimulus. First the interest was focused on threshold singularities in simple metals. The topic was thoroughly discussed
The Euglycemic Hyperinsulinemic Clamp (EHC) is the most widely used experimental procedure for the determination of insulin sensitivity. In the present study, 16 subjects with BMI between 18.5 and 63.6 kg/m(2) have been studied with a long-duration (5 hours) EHC. In order to explain the oscillations of glycemia occurring in response to the hyperinsulinization and to the continuous glucose infusion
Caveolae are small flask-like invaginations on the plasma membrane that contain both G-proteins aim G-protein coupled receptors. Consequently, these structures have been implicated to serve a role in transmembrane signaling. Bradykinin (BK) is a potent vasoactive peptide that acts through B2 BK receptors to stimulate both Gaq and Gai. DDT1 MF2 smooth muscle cells were used to show that eaveolae co
In this report, we show that the vasoactive peptide agonist bradykinin (BK) when bound to B2 BK receptors on DDT1 MF-2 smooth muscle cells promotes the recruitment and sequestration of the occupied receptors and the receptor- coupled G-protein α subunits Gα(q) and Gα(i) in caveolae. Association of ligand receptor complexes and Gα subunits with caveolae was indicated by their co-enrichment on densi
In linguistics and in the philosophy of language it is standardly assumed that know is a factive verb, meaning that a sentence such as X knows that p, when uttered in its positive declarative form, presupposes, in fact entails, the truth of its complement. A problem for this analysis is the fact that the verb know can be used non-factively in contexts where it is evident that the proposition expre
