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Investigating the Galactic center offers unique insights into the buildup and history of our Galaxy and is a stepping stone to understand galaxies in a larger context. It is reasonable to expect that the stars found in the Galactic center might have a different composition compared to stars found in the local neighborhood around the Sun. It is therefore quite exciting when recently there were repo
Background: Drying is an important method to preserve food products. Although many traditional drying technologies (hot air, freeze, microwave drying) have been applied successfully to various food products, each drying technique has its own advantages and disadvantages. Novel drying methods such as infrared drying, have become very popular. Scope and approach: This study gives an overview on the
Low- and medium-spin negative-parity bands of Os187 have been studied using the AFRican Omnipurpose Detector for Innovative Techniques and Experiments (AFRODITE) array, following the W186(He4,3n)Os187 reaction at a beam energy of 37 MeV. In the current work, all the previously known bands have been significantly extended and three new bands have been added to the level scheme. The angular distribu
Objective: The purpose of this paper is to demonstrate feasibility of a novel closed-loop controlled therapy for prevention of hypertension in the heartbeating brain-dead porcine model. Methods: Dynamic modeling and system identification were based on in-vivo data. A robust controller design was obtained for the identified models. Disturbance attenuation properties, and reliability of operation of
Background: The repertoire of measures of walking in Rett syndrome is limited. This study aimed to determine measurement properties of a modified two-minute walk test (2MWT) and a modified Rett syndrome-specific functional mobility scale (FMS-RS) in Rett syndrome. Methods: Forty-two girls and women with Rett syndrome (median 18.4 years, range 2.4–60.9 years) were assessed for clinical severity, gr
The glucose view of self-control posited glucose as the physiological substrate of self-control “resource”, which results in three direct corollaries: 1) engaging in a specific self-control activity would result in reduced glucose level; 2) the remaining glucose level after initial exertion of self-control would be positively correlated with following self-control performance; 3) restoring glucose
Fusobacterium necrophorum is a gram-negative anaerobic bacterium that is the causative agent of the invasive disease Lemierre's syndrome. In addition, it is also associated with peritonsillar abscess formation and otitis media in small children. Recent research has shown that F. necrophorum may be involved in pharyngotonsillitis especially in adolescent and young adults and that it may be the seco
Inside-out inner mitochondrial membranes free of matrix proteins were isolated from purified potato tuber (Solanum tuberosum L.) mitochondria and incubated with [γ-32P]ATP. Proteins were separated by SDS-PAGE and visualized by autoradiography. Phosphorylation of inner membrane proteins, including ATPase subunits, was strongly inhibited by the phosphoprotein phosphatase inhibitor NaF. We propose th
Preparedness and resilience planning for critical infrastructure networks requires evaluating the impact to the network when its components are disrupted. We extend the well-studied problem of component importance measures in single-commodity networks to multi-commodity networks by integrating a flow based multi-commodity optimization model with a multi-criteria decision analysis tool. A three-sta
Targeted genome editing technology can correct the sickle cell disease mutation of the β-globin gene in hematopoietic stem cells. This correction supports production of red blood cells that synthesize normal hemoglobin proteins. Here, we demonstrate that Transcription Activator-Like Effector Nucleases (TALENs) and the Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas9 nuclease
1. The presence of N-acetyltransferase in the crayfish brain (Pacifastacus leniusculus) was investigated. The arylalkylamines tryptamine and 14C-serotonin, are acetylated by crayfish brain homogenates with the acetyl donors 3H-acetyl coenzyme A and N, S-diacetylcysteamine, respectively.2. Resolution of serotonin metabolites by thin layer chromatography (chloroform/methanol/glacial acetic acid, 93
Von Willebrand disease (VWD) is the most common genetic bleeding disorder. VWD is caused by a deficiency or dysfunction of von Willebrand factor (VWF), a plasma protein that mediates the initial adhesion of platelets at sites of vascular injury and binds and stabilises coagulation factor VIII (FVIII) in the blood. Prophylaxis of surgical bleeding in patients with VWD requires consideration of the
