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A Masked Language Model for Multi-Source EHR Trajectories Contextual Representation Learning

Using electronic health records data and machine learning to guide future decisions needs to address challenges, including 1) long/short-term dependencies and 2) interactions between diseases and interventions. Bidirectional transformers have effectively addressed the first challenge. Here we tackled the latter challenge by masking one source (e.g., ICD10 codes) and training the transformer to pre

Towards sustainable heavy-duty transportation : Combustion and emissions using renewable fuels in a compression ignition engine

Transportation should become sustainable and available to everyone. Currently, transportation accounts for approx. one sixth of greenhouse gas (GHG) emissions globally, and heavy-duty trucks are responsible for almost 30% of that. When fossil diesel fuel is burned in a compression ignition engine, known as a diesel engine, it releases large amounts of CO2, a GHG, into the air. GHGs confine heat in

Selection of an optimal feature set to predict heart transplantation outcomes

Heart transplantation (HT) is a life saving procedure, but a limited donor supply forces the surgeons to prioritize the recipients. The understanding of factors that predict mortality could help the doctors with this task. The objective of this study is to find locally optimal feature sets to predict survival of HT patients for different time periods. To this end, we applied logistic regression to

Continuity of Theory Structure : A Conceptual Spaces Approach

By understanding laws of nature as geometrical rather than linguistic entities, this paper addresses how to describe theory structures and how to evaluate their continuity. Relying on conceptual spaces as a modelling tool, we focus on the conceptual framework an empirical theory presupposes, thus obtain a geometrical representation of a theory’s structure. We stress the relevance of measurement pr

The surface emissions trap: A new approach in indoor air purification.

A new device for stopping or reducing potentially irritating or harmful emissions from surfaces indoors is described. The device is a surface emissions trap prototype and consists of an adsorbent sheet with a semipermeable barrier surrounded by two thin nonwoven layers. The trap may be applied directly at the source of the emissions e.g. at moisture-affected floors and walls, surfaces contaminated

From imprinting to microcontact imprinting-A new tool to increase selectivity in analytical devices.

Molecular imprinting technology has been successfully applied to small molecular templates but a slow progress has been made in macromolecular imprinting owing to the challenges in natural properties of macromolecules, especially proteins. In this review, the macromolecular imprinting approaches are discussed with examples from recent publications. A new molecular imprinting strategy, microcontact

Immunomodulating activity of quinolones: review.

Fluorinated quinolones exert their bactericidal activity by inhibiting bacterial type II topoisomerases. At therapeutic concentrations, quinolones superinduce interleukin-2 (IL-2) and interferon-gamma production by mitogen-activated human peripheral blood T lymphocytes. At the molecular level, a stronger activation of the nuclear factor AP-1 ('activator protein-1') is observed in cells incubated w