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Cytotoxicity of adenovirus antibody aggregates : sensitivity to different cell strains, and inhibition by hexon antiserum and by complement

Adenovirus antibody aggregates under defined conditions are cytotoxic in vitro. All members of adenovirus groups I, II, and III caused toxicity upon aggregation. The toxicity of the clusters is exerted by the virions. Toxicity is temperature dependent and may be caused by a mechanism similar to that used in viral penetration. Cells permitting direct viral penetration were all sensitive to the toxi

Gut-associated lymphoid tissue: a microbiota-driven hub of B cell immunity

The diverse gut microbiota, which is associated with mucosal health and general wellbeing, maintains gut-associated lymphoid tissues (GALT) in a chronically activated state, including sustainment of germinal centers in a context of high antigenic load. This influences the rules for B cell engagement with antigen and the potential consequences. Recent data have highlighted differences between GALT

Anti-Sufism in Early Qajar Iran : Āqā Muḥammad ‘Alī Bihbahānī (1732–1801) and His Risāla-yi khayrātiyya

With the revival of the Ni‘matullāhī Order in late eighteenth-century Iran, the confrontation between uṣūlī ‘ulamā’ and Sufis gained new momentum. While the relationship between official Iranian Shiism and organized Sufism had been strained since the rise of the Safavids, the firm establishment of uṣūlism among Shii ‘ulamā’ and the Sufi revival in the late eighteenth century initiated a polemical

Thinking the Human System : The Application of Humanities and Social Science Reasoning to Societal Problems

Between 1967 and 1972, Swedish futures studies emerged as a distinct political and intellectual endeavor. In this development, the humanities and social sciences played a special role, especially through the idea that human knowledge and knowledge about a “human system” could be brought to bear on societal problems and used to forge a new approach to the future. We focus here on two scholars, hist

Tourism and Travel during the Cold War : Negotiating Tourist Experiences across the Iron Curtain

The Iron Curtain was not an impenetrable divide, and contacts between East and West took place regularly and on various levels throughout the Cold War. This book explores how the European tourist industry transcended the ideological fault lines and the communist states attracted an ever-increasing number of Western tourists. Based on extensive original research, it examines the ramifications of to