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The interaction between water and land greatly affected the change of the riparian ecosystem service value (ESV) under the background of rapid regional development. In order to analyze the change of ESV, this study combined the Logarithmic Mean Divisia Index (LMDI) and the P (pressure)-S (state)-R (response) framework to exploring its driving factors based on the ESV accounting method improved by

This document is created within the research project Nordic Fire and Rescue Services in the Twenty First Century (FIRE21). In this project, the fire and rescue services are seen as both governed by, and dependent on, formal and informal networks. A fundamental assumption in the research project is that efficient emergency management is dependent on efficient problem-solving in these networks. As a

FLT3 kinase has become an attractive drug target in AML with up to 30% of cases harboring internal-tandem-duplication (ITD) mutations. For these, conferring a worse prognosis and decreased overall survival, several FLT3 tyrosine kinase inhibitors (TKIs) are currently being tested in clinical trials. However, when using these drugs as monotherapy, the problem of short duration of remissions and hig

Timing of return to the breeding area presumably optimizes breeding output in migrants. How timing affects the other components of fitness — survival, has been comparatively little studied. Returning too early in spring is expected to be associated with high mortality in insectivorous migrants when weather conditions are still unsuitable. Yet, males in particular arrive early to get access to the

Purpose The aim of this study was to evaluate the long-term effect of 2 years of adjuvant tamoxifen compared with no systemic treatment (control) in premenopausal patients with breast cancer over different time periods through long-term (> 25 years) follow-up. Patients and Methods Premenopausal patients with primary breast cancer (N = 564) were randomly assigned to 2 years of tamoxifen (n = 276) o

This paper investigates the potential of an infant intervention to improve life expectancy, contributing to emerging interest in the early life origins of chronic disease. We track individuals from birth to death, and are able to identify age and cause of death. The intervention was pioneered in Sweden in 1931–1933, and appears to have been pivotal in the emergence of universal infant care program

In the US, whistle blowers who help uncover illegal offlabel promotion are usually awarded 15-25 percent of any recovered damages. Does incentivizing informants deter off-label drug marketing – and should other countries follow suit?

Background. Gynecologic examination is a common measure in reproductive health care. Many women experience the examination as a more or less negative event, with shortcomings in the examiner's behavior. The aim of the study was to describe, in terms of critical incidences, women's experiences concerning the personnel's behavior in the situation of gynecologic examination. Methods. The informants w

Modelers seeking to help inform decisions about insurance (public or private) coverage of the cost of pharmaceuticals or other health care interventions face various methodological challenges. In this review, which is not meant to be comprehensive, we cover those that in our experience are most vexing. The biggest challenge is getting decision makers to trust the model. This is a major problem bec

Quasi-experimental study of effects of an organizational intervention on staff and patients over a 8 year perspective; Before, under and after an organizational change. Effects on staff are staff-turnover, fatigue and burnout (n=268) on Three wards including the intervention ward. Independent variables are staff demographics, education, experience, job status, sick-leave and responses on a burn-ou

When a limiting resource (e.g. food) varies drastically between years, and population density is measured in the conventional way as individuals per area, demographic processes such as productivity and survival may erroneously be considered density-independent. We tested the hypothesis that if the variation in a limiting resource is not taken into account in the density measure, this may lead to e

The rapid growth of traffic induced by Internet services makes the simple over-provisioning of resources not economical and hence imposes new requirements on the dimensioning methods. Therefore, the problem of network design with the objective of minimizing the cost and at the same time solving the tradeoff between maximizing the service data flows and providing fair treatment of all demands becom

Popular Abstract in Swedish För att förstå på vilket sätt viktiga pollinerande insekter påverkas av det omgivande landskapets struktur och innehåll, har jag studerat populationer av humlor (fam. Bombus). Jag har också gjort en analys av sambandet mellan jordbruksintensitet of landskapets komplexitet. Mina studier har utförst i Skåne och jag har valt studieområden bl.a. baserat på hur stora åkrar oTo investigate recent declines in bumblebee populations, I carried out landscape analyses, made field studies of bumblebees, flowering plants and pollination in an agricultural region in southernmost Sweden. Studies were carried out in landscapes of contrasting agricultural intensity and land-cover configuration; "simple" landscapes highly dominated by large crop fields, and "complex" with mixed f

PURPOSE: The aim of this study was to test a model proposing that the relationship between personality factors and women's quality of life (QoL) is mediated by degree of depression and the way in which every day activity and general health were appraised. Specifically, the paper addressed the mediating contribution of activity. METHODS: A sample of 488 women, 38 or 50 years old, filled out questio