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Low serum apolipoprotein (Apo) A1 concentrations and high serum ApoB concentrations may be better markers of the risk of cardiovascular disease than high-density lipoprotein (HDL) and low-density lipoprotein (LDL). However, the associations between modifiable lifestyle factors and Apo concentrations have not been investigated in detail. Therefore, this study investigated the associations between A

Background: Variation in the 10 toll-like receptor (TLR) genes has been significantly associated with allergic rhinitis (AR) in several candidate gene studies and three large genome-wide association studies. These have all investigated common variants, but no investigations for rare variants (MAF≤1%) have been made in AR. The present study aims to describe the genetic variation of the promoter and

Background. Exposure to allergens plays a role in the development of atopic sensitization and influences allergic phenotype. House dust mites (HDM) are a common source of aeroallergens in many parts of the world. The relationship between indoor environment factors such as temperature, moisture/humidity, and ventilation and HDM allergen load is complex. Methods. Part of a larger study into the heal

Bank voles are known reservoirs for Puumala hantavirus and probably also for Ljungan virus (LV), a suggested candidate parechovirus in type 1 diabetes etiology and pathogenesis. The aim of this study was to determine whether wild bank voles had been exposed to LV and if exposure associated to autoantibodies against insulin (IAA), glutamic acid decarboxylase 65 (GADA), or islet autoantigen-2 (IA-2A

The social determinants of health form a complex and dynamic web, shaping both populationand individual health and disease. The built environment and especially human dwellingsinfluence health in many ways. Associations between factors such as dampness, mouldgrowth, heating/insulation, and crowding on the one hand and respiratory health andinfectious diseases on the other hand have been studied in

Objectives: Recent evidence from the 7-year followup of the Pediatric Osteoporosis Prevention (POP) study indicates an inverse correlation between years of participation in a physical activity (PA) intervention and fracture risk in children. However, we could not see a statistically significant reduction in fracture risk, which urged for an extension of the intervention. Setting: The study was con

Harvesting of wood for bioenergy purpose will probably increase in importance in the future, in order to replace fossil fuel. However, the environmental impact of increased harvesting might be considerable, e.g. on soil and water chemistry, biodiversity and long-term productivity, and in this study we investigate thresholds for sustainable harvesting volumes. The study is based on scientific revie

Background The process of delivery entails potentially traumatic events in which the mother or child becomes injured or dies. Midwives and obstetricians are sometimes responsible for these events and can be negatively affected by them as well as by the resulting investigation or complaints procedure (clinical negligence). Objective To assess the self-reported exposure rate of severe events among m