Popular Abstract in English The prevalence of type 2 diabetes (T2D) and cardiovascular disease (CVD) is increasing in epidemic proportions around the globe. This epidemic accounts for huge health and economic burdens as a leading cause for morbidity and mortality. The development of these diseases is very complex and involves both genetic and lifestyle factors. The shift to sedentary lifestyles anType 2 diabetes (T2D) and cardiovascular disease (CVD) are highly prevalent complex diseases that result from lifestyle and genetic factors. Gene-lifestyle interactions are also believed to contribute to the etiology of these diseases. The aim of this thesis was to investigate gene-lifestyle interactions using the strongest T2D and CVD susceptibility genetic loci and to understand the causal natur

This thesis presents the results of an investigation into BIM implementation prerequisites emerging as a set of procedural supporting mechanisms that may enable design, construction and operating (DCO) organisations to advance their deployment of Building Information Modelling (BIM) technology, and improve construction project outcomes. Today, BIM is centre-stage within the construction sector the

This dissertation considers two different aspects of health economics; (i) stated preference methods and (ii) empirical analyses of equity. The first essay deals with the issue of the choice of econometric models when analysing data from a closed-ended contingent valuation survey in health economics. The features of provision, either compulsory or voluntary, and the fact that certain individuals m

Stratagems adopted by democratic leaders to try to insinuate, or anchor, a preferred course of action into the larger collective will have a variety of repercussions. Beyond the apparent success of the venture itself, the long-term integrity of the democratic fabric may be at stake if simmering rancour and discontent is left unheeded. These questions would seem particularly pertinent when studyi

The objectives of the work presented in this thesis have been to develop molecular methods for (i) detection of Clostridium botulinum in food and clinical samples, and (ii) monitoring the expression of the neurotoxin gene, cnt, during different growth phases and under different growth conditions. For the diagnosis of botulism, a real-time PCR-based method including an internal amplification contr

Importance: There is currently no consensus as to which biomarkers best predict longitudinal tau accumulation at different clinical stages of Alzheimer disease (AD). Objective: To describe longitudinal [18F]RO948 tau positron emission tomography (PET) findings across the clinical continuum of AD and determine which biomarker combinations showed the strongest associations with longitudinal tau PET

Sammanfattning Selektiva distributionsavtal används inom många branscher som ett sätt att reglera handeln med produkter och som ett verktyg för att selektera återförsäljarna. Det senaste året har dessa avtal kommit att nyttjas även inom klockbranschen. Det är en speciell bransch där varumärkena får allt större betydelse och det bidrar till en starkare position för de företag som äger och levererar

Title: Music-esthetical productions in the educational work - a case study of the Allvar Gullstrand highschool. Problem: A problem associated with working with project- and thematic studies which result in esthetical productions is that it often demands extra effort and time beyond the schedule to carry the production through. There are no instructions saying that schools are to work with this ki

Kustnära putsade fasader ställda mot havet har av rapportförfattarna observerats vara i sämre skick än fasader med riktning inåt landet i samma miljö. Detta leder till hypotesen att saltvatten påskyndar nedbrytningen av kalk/cementbruk genom saltsprängning eller annan form av vittringsprocess. Ingen form av kemisk nedbrytning är rimlig då salt inte reagerar med putsens vanliga beståndsdelar. SvensOf rendered façades in coastal environment Rendered coastal-facing façades have been observed to be in worse condition than those facing away from the coastline in the same environment. This leads to the hypothesis that salt water accelerates the deterioration of render, either by salt blasting or through other forms of weathering processes. Since salt does not react with common render components,

It has often been argued that money and modern monetary economies have occasioned a comprehensive rationalisation of society. Money has often been viewed as being socially destructive, while it is said that the modern monetary economy has had inescapable consequences for society, culture, and people’s daily lives. This thesis considers the introduction of computerised systems for handling digital

The EU governance of food safety and GM food and feed has gone through significant changes since the BSE crisis and food scares during the 1990s. This work focuses on one particular new feature; the role of stakeholders representing the food chain: biotech associations, farmer organizations, food and feed processors, consumer organizations and environmental NGOs. These stakeholders are not merely

The purpose of this socio-legal dissertation is to examine the role of the district court in the handling of custody disputes, from the standpoint of the child's best interest. More specifically, the focus is partly on the relationship between the family and society during district court proceedings, and partly on the relationship between civil law and public law procedure that is to say between t

The first chapter develops a theoretical model of marriage and divorce. The model has two periods and assumes Pareto efficient time allocations. There is a risk of divorce in the second period, which is modeled as exogenously given. The second chapter utilizes the model developed in the previous chapter to analyze the equality between married men and women. Equality is defined as the spouses' rel

This thesis consists of three empirical studies on asset-prices in international financial markets. The purpose is three-fold. First, to evaluate whether good predictions of economic variables may be obtained by pooling information from a broad group of financial variables. Second, to formulate asset-pricing models from seven established stock markets. Third, to evaluate the asset-pricing models i