BACKGROUND: Differential gene expression in adipose tissue during diet-induced weight loss followed by a weight stability period is poorly characterized. Markers of these processes may provide a deeper understanding of underlying mechanisms. OBJECTIVE: We aimed to identify differentially expressed genes in human adipose tissue during weight loss and weight maintenance after weight loss. DESIGN:

This research report has two objectives, both focusing on the supply chain flows passing or crossing the Öresund maritime area. The first objective is to identify and describe the flows in Öresund and the risks for disturbances in those flows before and after the opening of the Öresund Link in July 2000. With the opening of the Öresund Link a new goods and passenger flow was created. As a resul

Tensins are large intracellular proteins believed to link the extracellular matrix to the cytoskeleton via integrins. Tensins are multidomain proteins consisting of homologous C1, PTPase, C2, SH2 and PTB domains. Full-length Tensin proteins can undergo cleavage inside cells, thus yielding domains in isolation that may have discrete subcellular localisations and downstream effects. We expressed dif

OBJECTIVE: To analyse the outcome of minor amputations (through, or distal to, the ankle joint) in patients with diabetes. METHOD: All diabetic patients in a defined population undergoing one or more minor amputation between 1982 and 2006 were investigated according to a standardised protocol and were followed until final outcome (healing or death). A total of 410 consecutive amputations in 309 p

Objective: Intranasal immunization with a fusion protein of the ApoB100-derived peptide p210 and the cholera toxin B subunit (CTB-p210) has previously been shown to induce mucosal tolerance and reduce atherosclerosis development, but the exact mode of action remains to be elucidated. Recent studies have indicated an important role for B cells in mucosal tolerance, in particular by induction of reg

Background: Neuropathic pain is an increasingly prevalent condition and has a major impact on health and quality of life. However, the risk factors for the development and maintenance of neuropathic pain are poorly understood. Clinical, genetic and psychosocial factors all contribute to chronic pain, but their interactions have not been studied in large cohorts. The DOLORisk study aims to study th

Objective: This study aimed to evaluate the effects of varied lifestyle intervention programs designed to ameliorate excess gestational weight gain (GWG) in pregnant women with overweight or obesity compared with standard care, including effects on pregnancy outcomes. Methods: Seven clinical centers conducted separate randomized clinical trials to test different lifestyle intervention strategies t

Background/aim: More knowledge is needed about the role of perceived control in the associations between different perceptions of daily occupations and positive health outcomes. The aim was to explore the associations between different subjective perceptions of daily occupations, in terms of occupational balance, occupational meaning, occupational value and satisfaction with occupations, and life

Introduction Assessing work ability and sickness certification are considered problematic by many physicians and education and implementation of guidelines to improve knowledge and skills has been requested. Our aim was to study the association between such interventions and physicians' sick-listing practices. Methods A web-based questionnaire was sent to all physicians working in primary care, ps

BACKGROUND AND PURPOSE: There are few studies on the prognosis after primary intracerebral hemorrhages, and they reported big differences in mortality rates. Our aim was to evaluate mortality and stroke recurrence rates in relation to hemorrhage characteristics, demographic and clinical factors, in a large unselected patient cohort. METHODS: We analyzed consecutive cases of first-ever primary intr

“The death of distance” has become the battle cry of a modern generation of managers, policy makers and scientists who embrace the new globalized economy and its promise of frictionless exchange across the world. While highly influential, this view does not, however, stand unchallenged. Over the last 15 years, there has been a growing interest in the geographical clustering of industry. Well-known

During the 1980s and the 1990s several researchers have described new organisational features and a new organisational form in multinational enterprises, linked to a variety of theoretical approaches. Can the new organisational features be analysed from a consistent theoretical basis, and can, hereby, a new organisational form be distinguished from earlier forms? The purpose of this dissertation i

Cadastral Systems have developed during the latest decades, impelled by improved information technology. Cadastral projects have become more strategic in a development perspective, with expected long-term returns in economic growth. An improvement of an existent information system requires an understanding of the basis of the current model, its coverage and the processes of change. The land unit