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The drafters of the 1990 Dublin Convention knowingly and willfully disregarded divergences among Member States' protection systems. Like a boomerang, the fallacy of this approach has now reappeared in cases where asylum seekers have challenged transfers under the Convention, tasking judges to tackle a problem which its drafters avoided. The core issue of this article is whether and when such diver

Cleveland (1979) is usually credited with the introduction of the locally weighted regression, Loess. The concept was further developed by Cleveland and Devlin (1988). The general idea is that for an arbitrary number of explanatory data points x_i the value of a dependent variable is estimated ŷ_i. The ŷ_i is the fitted value from a dth degree polynomial in x_i

It is today commonplace that games and virtual worlds are not only multi-billion dollar businesses but also momentous socio-cultural phenomena that require critical attention. Massively Multiplayer On-line Games (MMOGs) are these days becoming recognized not only as grounds for play within ‘magic circles’ but also as complex and significant social spaces with 24-7 access to the millions of gamers

This chapter deals with political mobilisation and participation in social media. The main focus is on the impor¬tance of Internet-mediated social networks in providing a “media filter”, functioning as a kind of collective gatekeeper to spread news and information perceived as important, in contrast to the image of the single individual media consumer faced with an in¬surmount¬able mass of informa

BACKGROUND: There is a need to develop an instrument that measures both the parents' experiences and sense of security during the first postnatal week. No instrument measuring positive dimensions which can be influenced and supported by the postnatal health care has been developed. OBJECTIVE: The aim of the study was to develop a specific instrument to assess both mothers' and fathers' postnatal s

The DyDOC model simulates the C dynamics of forest soils, including the production and transport of dissolved organic matter (DOM), on the basis of soil hydrology, metabolic processes, and sorption reactions. The model recognizes three main pools of soil C: litter, substrate (an intermediate transformation product), and humic substances. The model was used to simulate the behavior of C in the 0 ho

Background and aims: Extracellular matrix (ECM) remodeling is one of the key components in the formation of vulnerable atherosclerotic plaques and cardiovascular events. We recently showed that the full-length ECM-proteoglycan osteoglycin was associated with plaque vulnerability and future cardiovascular events. In the present study, we aimed to investigate the association of cleaved osteoglycin w

Context: Glucose-dependent insulinotropic peptide (GIP) and meal ingestion increase subcutaneous adipose tissue (SAT) perfusion in healthy individuals. The effects of GIP and a meal on visceral adipose tissue (VAT) perfusion are unclear. Objective: Our aim was to investigate the effects of meal and GIP on VAT and SAT perfusion in obese individuals with type 2 diabetes mellitus (T2DM) before and af

Objective: To examine the association of physical activity (PA), measured by accelerometry, to hemoglobin AIC (HbA1c) and oral glucose tolerance test (OGTT) outcomes in children who were multiple persistent confirmed autoantibody positive for type 1 diabetes (T1D). Methods: The Environmental Determinants of Diabetes in the Young (TEDDY) multinational study followed children from birth. Children ≥3

Objective: To analyze the effectiveness and safety of growth hormone (GH) replacement treatment in adult patients with Langerhans cell histiocytosis (LCH) and GH deficiency (GHD) enrolled in KIMS (Pfizer International Metabolic Database). Patients and methods: Patients with LCH and GHD were studied at baseline and some of them after 1 year of GH treatment. The effectiveness of GH is presented as c

In a large, multiethnic cohort of youths with obesity, we analyzed pathophysiological and genetic mechanisms underlying variations in plasma glucose responses to a 180 min oral glucose tolerance test (OGTT). RESEARCH DESIGN AND METHODS Latent class trajectory analysis was used to identify various glucose response profiles to a nine-point OGTT in 2,378 participants in the Yale Pathogenesis of Youth

INTRODUCTION: Since 2005, disease-related human genetic diversity has been intensively characterized using genome-wide association studies (GWAS). Understanding how and by whom this work was performed may yield valuable insights into the generalizability of GWAS discoveries to global populations and how high-impact genetics research can be equitably sustained in the future.MATERIALS AND METHODS: W

To assess the biodiversity consequences of contemporary land-use trends in Northern Europe, where agriculture is being replaced by forestry, we need a better knowledge of the contributions of constituting habitats to biodiversity. Here, we use purposefully collected data from 87 sites to model how agricultural habitats, including semi-natural pastures, sown temporary grassland (leys), cereal crops