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Background and aim: The Receptor Activity Modifying Proteins (RAMPs) are a group of accessory proteins, of which there are three in humans, that interact with a number of G-protein coupled receptors (GPCR) and play various roles in regulation of endocrine signaling. Studies in RAMP3 knockout (KO) mice reveal an age related phenotype with altered metabolic regulation and high bone mass. To translat

Purpose: The aim of this work was to investigate, in patients with newly diagnosed Graves’ disease (GD), the frequency of islet autoantibodies including autoantibodies against Zink transporter 8 (ZnT8A), as well as to investigate the relation between thyroid autoantibodies, islet autoantibodies and diabetes both before GD diagnosis and at follow-up. Methods: Blood samples from 278 patients with ne

Safe drinking water is delivered to the consumer through kilometres of pipes. These pipes are lined with biofilm, which is thought to affect water quality by releasing bacteria into the drinking water. This study describes the number of cells released from this biofilm, their cellular characteristics, and their identity as they shaped a dri

In this chapter, we discuss the need for deeper knowledge about the relation between people’s daily activities and their electricity use and how to increase our knowledge through time use surveys and the visualization of aggregate activity patterns. To understand people’s energy consumption and how to improve energy efficiency or reduce demand during certain peak hours requires an understanding of

In this paper I draw on two case studies of how environmental impacts are assessed in large scale golf developments to illustrate the political ecology of leisure and how countrysides are reshaped to cater for elite consumption (McCarthy 2008). In 2008 Trump International Golf Links Scotland gained permission to build a golf resort, potentially the largest in the UK, along the Aberdeenshire coast.

The private garden is one of the most important sites for people’s everyday interactions with nature. Although sometimes just consisting of a lawn, a few shrubs and maybe a flower bed, it provides a number of situations where the owner has to reflect on and handle biodiversity and sustainability issues in relation to modern lifestyle. This paper will discuss different aspects of sustainability in

Our society is becoming more and more dependent upon the reliable function of a number of vital socio-technical systems. These systems are often being referred to as critical infrastructures, or lifeline systems, indicating their importance for supporting a nation’s economy and social well-being. In the present paper a method is presented for assessing the capability of those actors involved in re

Purpose of this paper The paper describes and examines the information flow in three fish supply chains, when the package is treated as an information carrier. Included is an evaluation of two supply chain mapping techniques for examining the interfaces for the achievement of better traceability and by this supply chain and logistic efficiency. Design/methodology/approach The research is based on

This paper deals with socioeconomic differences in mortality among infants, children, adults, and elderly during the period of mortality decline in the nineteenth century. It uses multilevel Cox regression controlling for shared unobserved factors at the family level, and also compares the magnitude of the observed differences between socioeconomic groups with the impact of unobserved factors at f

Universities are widely understood to be sites of free expression, knowledge-seeking institutions that serve the public good while encouraging personal development of individuals. They typically uphold and communicate institutional integrity and ethics, seeking to encourage open communication, equip students with critical thinking, and foster civil participation. For the Social Sciences, questions

Klimatförändringar leder till en ökad mängd nederbörd, vilket medför betydande utmaningar i urbana miljöer. Regnbäddar, en typ av blågrön lösning, kan implementeras för att bidra till hållbar dagvattenhantering genom att rena och fördröja dagvatten. Detta arbete baseras på en fallstudie på regnbäddarna längs Neptunigatan i Malmö, Sverige. Studien innefattade bland annat att utvärdera implementerin