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Challenging Diabetes in Rural Areas : Aspects of Nutrition

Diabetes is an escalating health concern affecting approximately 152.6 million people globally in rural areas, with a significant rise in low- and middle-income countries where over 75% of affected adults live. These populations face unique challenges, including delayed diagnosis, limited access to specialized care, and economic hardships, leading to severe complications such as cardiovascular dis

The Impact of Variable DOC Concentrations on Acidification Assessments

Dissolved organic carbon (DOC) affects the acidity in soil and lake waters and buffers both against acidification and against recovery from acidification. Current acidification assessments, based on the widely used MAGIC (Model of Acidification of Groundwater In Catchments) model, often assume constant DOC concentrations through time, but observations suggest this assumption may not be warranted.

Transgender and Gender-Diverse Individual's Experiencesof Openness and Concealment at Work in Swede

The workplace is an important part of many people's lives. Many transgender and gender-diverse (TGD) individuals have negativeexperiences of their workplace due to discrimination and cisnormativity. Whether or not to be open about TGD experiences, andthe degree of openness, is something many TGD individuals struggle with at work. Openness is related to well-being and job satis-faction and is thereThe workplace is an important part of many people's lives. Many transgender and gender-diverse (TGD) individuals have negative experiences of their workplace due to discrimination and cisnormativity. Whether or not to be open about TGD experiences, and the degree of openness, is something many TGD individuals struggle with at work. Openness is related to well-being and job satisfaction and is ther

Analysis of genetic variant associated with heart failure mortality implicates thymic stromal lymphopoietin as mediator of strain-induced myocardial fibroblast-mast cell crosstalk and fibrosis

Heart failure (HF) is a leading cause of death and disability globally. Heritable factors and the extent and pattern of myocardial fibrosis are important determinants of outcomes in patients with HF. In a genome-wide association study of mortality in HF, we recently identified a genetic polymorphism on chromosome 5q22 associated with HF mortality. Here, we sought to study the mechanisms by which t

Barking up the wrong tree? : A guide to forest owner typology methods

Creating typologies of forest owners is a common approach for analyzing and understanding heterogeneity in responses to forest policies and management practice uptake. While many forest owner typologies have been developed, only a few quantitative methods dominate the field with little information on how methodological choice affects outcomes. In this study we compare five methods for quantitative

Research and education form competing activity systems in externally funded doctoral education

Several authors have described how the formalization of recent decades has steered doctoral education towards structured curricula, more managerial control and new models for supervision. Largely absent from these accounts, however, is if and how doctoral education has been affected by the concurrent changes in research governance, in particular by the ‘projectification’ of research. For this studSeveral authors have described how the formalization of recent decades has steered doctoral education towards structured curricula, more managerial control and new models for supervision. Largely absent from these accounts, however, is if and how doctoral education has been affected by the concurrent changes in research governance, in particular by the ‘projectification’ of research. For this stud

Glycolytic enzyme Enolase-1 regulates insulin gene expression in pancreatic β-cell

Enolase-1 (Eno1) plays a critical role in regulating glucose metabolism; however, its specific impact on pancreatic islet β-cells remains elusive. This study aimed to provide a preliminary exploration of Eno1 function in pancreatic islet β-cells. The findings revealed that the expression of ENO1 mRNA in type 2 diabetes donors was significantly increased and positively correlated with HbA1C and neg

Metamorphic titanite-zircon pseudomorphs after igneous zirconolite

The formation of metamorphic zircon after baddeleyite is a well-known reaction that can be used to date the metamorphism of igneous silica-undersaturated rocks. By contrast, metamorphic minerals formed after igneous zirconolite have rarely been reported. In this paper, we document metamorphic titanite + zircon pseudomorphs formed from the metamorphic breakdown of igneous zirconolite in syenodiorit

Building organizational adaptive capacity in the face of crisis : Lessons from a public sector case study

While organizations providing critical services to society must have the ability to anticipate and prepare for foreseeable threats, they also need to develop a capacity to adapt in the face of unforeseen challenges and crises. While adaptive capacity becomes manifested in a specific situation through the concrete adaptations carried out by an organization, the preconditions to adapt exist already

Prior electrocardiograms not useful for machine learning predictions of major adverse cardiac events in emergency department chest pain patients

At the emergency department (ED), it is important to quickly and accurately determine which patients are likely to have a major adverse cardiac event (MACE). Machine learning (ML) models can be used to aid physicians in detecting MACE, and improving the performance of such models is an active area of research. In this study, we sought to determine if ML models can be improved by including a prior

Human Genetic Variation at rs10071329 Correlates with Adiposity-related Traits, Modulates PPARGC1B Expression, and Alters Brown Adipocyte Function

Human genetic variation in PPARGC1B has been associated with adiposity, but the genetic variants that affect PPARGC1B expression have not been experimentally determined. Here, guided by previous observational data, we used CRISPR/Cas9 to scarlessly edit the alleles of the candidate causal genetic variant rs10071329 in a human brown adipocyte cell line (hBAs). Switching the rs10071329 genotype from

Experiences of participating in a group-based sensory modulation intervention for mental health service users

BACKGROUND: People with mental health issues often experience difficulties with sensory modulation affecting occupational engagement. Research conducted in inpatient units has shown positive effects of individual sensory modulation interventions, however, research on experiences of group-based interventions in outpatient units is limited. Hence, a group-based sensory modulation intervention was ad

Gender Smart Mobility : Concepts, Methods, and Practices

This book presents gender and diversity in smart transport as a cutting-edge issue in urban contexts around the globe. It addresses new challenges and possibilities related to the smart transport sector. It demonstrates how gender and diversity are entangled in concepts and various forms of current smart mobility practices in policy, planning, and innovation. Gender Smart Mobility is presented as

Lessons learned about openness : EndNote course as an open learning resource

Background: In a workshop about working with the Canvas learning platform, three librarians at Lund University started a project to create a resource for the reference management program EndNote. We started in January 2020 and launched our Canvas course with EndNote X9 in August 2020. In 2021, the entire course was updated to adapt to EndNote 20 and we also added an English version due to request.