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Finansinspektionens roll i kontrollen av den svenska finansmarknaden - med fokus på det finansiella företaget

De senaste åren av ekonomisk instabilitet har påverkat finansmarknaden och samhället både nationellt och globalt. Uppsatsen behandlar Finansinspektionens roll i att kontrollera den finansiella marknaden med syftet att begränsa eller förhindra ekonomisk instabilitet och finanskriser. Finansinspektionen ansvarar för tillsynen över svenska finansiella företag, utländska finansiella företag med verks

Riskbaserad brandteknisk analys av diskotekslokaler

The purpose of this study is to evaluate the safety of people located in discotheques in case of fire. A quantitative fire riskanalysis (QRA) for three different types of discotheques is carried out. The analysis is based on performance based codes from which fire protection alternatives are analysed. The results of the quantitative fire riskanalysis are described as risk profiles and average risk

Family matters! How storytelling can be used in the management communication in family-owned companies

The purpose of this thesis is to examine how a strong corporate brand identity can be created through organisational storytelling as a management communication tool. We have chosen to investigate family-owned companies as an empirical case due to the distinctive identity of this form of organisation, hence, the presence of a family in the business context. More specifically, we have investigated t

Translational and functional analyses of microRNAs in prostate cancer

The aims of this thesis were to identify microRNAs (miRNAs) with prostate cancer prognostic and diagnostic potential, to discover miRNAs with therapeutic capacity against prostate cancer, and to investigate if prostate specific antigen (PSA) is miRNA regulated. Prostate cancer is a globally spread disease with low mortality, but some patients develop an aggressive lethal form of prostate cancer w

Increased incidence of invasive bacterial disease in chronic obstructive pulmonary disease compared to the general population-a population based cohort study

Background: Innate defence mechanisms of the airways are impaired in chronic obstructive pulmonary disease (COPD), predisposing patients to lower respiratory tract infections, but less is known about the association with other infections. In this population-based cohort study, we investigated the associations between COPD and invasive bacterial disease by comparing incidence rates of bacteraemia i

A Panel of Kallikrein Marker Predicts Prostate Cancer in a Large, Population-Based Cohort Followed for 15 Years without Screening

Background: Prostate-specific antigen (PSA) has modest specificity for prostate cancer. A panel of four kallikrein markers (total PSA, free PSA, intact PSA, and kallikrein-related peptidase 2) is a highly accurate predictor of biopsy outcome. The clinical significance of biopsy-detectable cancers in men classified as low-risk by this panel remains unclear. Methods: The Malmo Diet and Cancer study

Fatty fish consumption and risk of latent autoimmune diabetes in adults.

It has been suggested that intake of fatty fish may protect against both type 1 and type 2 diabetes. Hypotheses rest on the high marine omega-3 fatty acid eicosapentaenoic acid+docosahexaenoic acid (EPA+DHA) and vitamin D contents, with possible beneficial effects on immune function and glucose metabolism. Our aim was to investigate, for the first time, fatty fish consumption in relation to the ri

Prognostic impact of early ventricular fibrillation in patients with ST-elevation myocardial infarction treated with primary PCI.

Current guidelines do not advocate implantation of cardioverter-defibrillators (ICD) for survivors of ventricular fibrillation (VF) during the first 48 hours of ST-elevation myocardial infarction (STEMI). However, contemporary studies in a real-life setting with long-term follow-up are lacking. We assessed the prognostic impact of early VF in a non-selected population of STEMI patients treated wit

Environmental Management Systems – a Way towards Sustainable Development in Universities

The economic development in the world today makes increased consumption of goods and travelling available for more people around the world than ever before. This results, however, also in increased production and spreading of substances that are hazardous both to human health and to the ecosystem globally. Therefore, education to increase knowledge, awareness, motivation, and action competence on

Alpha-1-microglobulin, heme-binding protein, reductase and antioxidant

This thesis describes structural and functional studies of alpha-1-microglobulin (a1m), a 26 kDa plasma and tissue protein that is evolutionarily well-conserved and belongs to the lipocalin superfamily. The lipocalins are polypeptides of 160-190-amino acids that are folded into an 8-stranded beta-barrel forming a pocket with a hydrophobic interior. a1m carries heterogeneous yellow-brown chromophor