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Survival after childhood cancer has improved dramatically during the past four decades, resulting in a five-year survival rate of 80% in children recently treated for cancer in the Nordic countries. However, these advances in treatment and survival has come at a price, and many survivors face significant treatment-induced sequelae, most of which only become clinically apparent many years after the
Atopic dermatitis is a chronic skin disorder with high prevalence, especially in the Nordic countries. Effective maintenance therapy during symptom-free episodes may prolong the time to eczema relapse according to a previously published clinical trial. The present study evaluates the cost-effectiveness of a barrier-strengthening moisturizer containing 5% urea, compared with a moisturizer with no a
Over the years, much information has been gathered about fires in fire investigation reports and statistics. This information may have been collected nationally by an agency or an insurance company, or locally by the local rescue service. The information thus gathered can be used to learn from these fires and thereby lead to improved fire safety in buildings. This paper describes a method for discover
In 1999 and 2004, we published reports on how the introduction of 20 males into a severely inbred and isolated population of Adders (Vipera berus) halted its decline towards extinction. The introduction significantly enhanced the population's genetic variability, which resulted in a dramatic increase in offspring viability and a rapid increase in numbers. Unfortunately, recently a new and unpreced
GENERAL AIM: To investigate how common single-nucleotide-polymorphisms (SNPs) that associate with cardiovascular disease (CVD) could be used in prevention and treatment of CVD. SUBJECTS: Subjects from the population-based Malmö-Diet-and-Cancer-(MDC)-Study (n=30447) and hypertensives from the Nordic-Diltiazem-(NORDIL)-Study (n=10881). METHODS AND RESULTS: A nine-SNP-lipid-genetic-risk-score was r
Previous research has found that weak institutions can hamper investment and alter patterns of trade. However, little is known about the impact of institutional quality on offshoring. This lack of knowledge is surprising, given that offshoring has become an important part of many firms' internationalization strategies. This study uses detailed firm-level data for the 1997-2005 period to examine th
In this study, user participation is suggested as a means, a process and role-playing between system users and developers in systems development. User participation in object-oriented contexts is observed from methodological and practical perspectives as a combined field of study. From the methodological perspective, three object-oriented methods are assessed according to NIMSAD, a method evaluati
