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The building and construction industry is responsible for around 40% of global greenhouse gas emissions, driving the urgent need for new regulations. As such, the life cycle assessment (LCA) methodology has become fundamental for evaluating environmental impacts. Despite the need for digital tools to support environmental performance evaluations, the lack of guidance on developing such tools hindeThe building and construction industry is responsible for around 40% of global greenhouse gas emissions, driving the urgent need for new regulations. As such, the life cycle assessment (LCA) methodology has become fundamental for evaluating environmental impacts. Despite the need for digital tools to support environmental performance evaluations, the lack of guidance on developing such tools hinde

Living statues and artificial humans have a long cultural history. They are awe-inspiring because they are entangled with existentialist questions about reality, especially as regards the uncertainty of being. This article explores how humanoid material culture in its different forms was involved in the interaction between myriad human and non-human entities in seventeenth-century Sweden and in th

Recent studies find that women are less competitive than men. This gender difference in competitiveness has been suggested as one possible explanation for why men occupy the majority of top positions in many sectors. In this study we explore competitiveness in children, with the premise that both context and gendered stereotypes regarding the task at hand may influence competitive behavior. A rela

This paper examines the implications of platforms as a repertoire for knowing and relating the intensities of pandemic restrictions on teaching and schoolwork. Building on platformisation in education, what work platforms do in unpredictable everyday pedagogical encounters is investigated. Specifically, the paper explores a methodological potential with platforms’ capabilities to pull some things This paper examines the implications of platforms as a repertoire for knowing and relating the intensities of pandemic restrictions on teaching and schoolwork. Building on platformisation in education, what work platforms do in unpredictable everyday pedagogical encounters is investigated. Specifically, the paper explores a methodological potential with platforms’ capabilities to pull some things

The new ACR/EULAR classification criteria for APS differ from the previous Sydney criteria by incorporating a broader range of clinical manifestations beyond venous/arterial thromboembolism and obstetric complications. These include microvascular disease, heart valve disease and thrombocytopenia. We applied both classification systems to a cohort of 139 individuals diagnosed with primary APS in So

Regulation of intracellular levels of reactive oxygen species (ROS) remains poorly understood. Aquaporin 3 (AQP3) facilitates the membrane transport of hydrogen peroxide (H2O2), a key ROS signaling molecule. Here we elucidate the molecular mechanism of AQP3 and show that its regulatory properties are both pH dependent and autoregulated by H2O2. Using single particle cryo-electron microscopy, we pr

This paper engages with the concept of periphery, as presented in Tamsma’s classic paper (1972), and reflects upon what has (or has not) changed in our approach to studying peripheries within regional economic geography over the past fifty or so years. In addition to providing reflections across time, it discusses the situation that Tamsma introduces the Netherlands periphery (the North) from the

As we become increasingly conscious of the entangled nature of human existence, we need to become more attuned to the needs of other species, and things on this planet we are bound to. This presents us with an opportunity to rethink in whose interest we approach architectural design, and to bring vital voices into the process that have – until now – been unable to make themselves heard. We conduct

The 1st Ecuadorian Dendrochronology Conference (ECUADENDRO 2025) took place in Daule, Ecuador, on January 23–24, 2025, with the generous sponsorship of the Tree-Ring Society. The event attracted 230 participants from 45 countries, bringing together leading experts in various subfields of tree-ring science, including dendroclimatology, dendroecology, dendrogeomorphology, dendroarchaeology, and cell

Dental caries and periodontitis account for a vast burden of morbidity and healthcare spending, yet their genetic basis remains largely uncharacterized. Here, we identify self-reported dental disease proxies which have similar underlying genetic contributions to clinical disease measures and then combine these in a genome-wide association study meta-analysis, identifying 47 novel and conditionally

The cost of treating cardiovascular disease (CVD) and diabetes is enormous and is set to rise in the coming years. Physical inactivity and sedentary behaviors are major risk factors for these diseases and are estimated to account for several million global deaths annually. Lifestyle interventions, particularly those aimed at enhancing physical activity levels, have a substantial favorable impact o

Often in clinical practice, a diagnosis of alcohol dependence or abuse does not provide enough information to establish an adequate treatment plan. Hence, multidimensional instruments have been constructed better to describe the extent and character of a patient's alcohol problem. The purpose of the current article is to present the AVI-R2, a self-report test that provides a standardized and diffe