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The pathophysiological mechanisms intersecting metabolic and neurodegenerative disorders include insulin resistance, which has a strong involvement of environmental factors. Besides central regulation of whole-body homeostasis, insulin in the central nervous system controls molecular signalling that is critical for cognitive performance, namely signalling through pathways that modulate synaptic tr

Using electronic health records data and machine learning to guide future decisions needs to address challenges, including 1) long/short-term dependencies and 2) interactions between diseases and interventions. Bidirectional transformers have effectively addressed the first challenge. Here we tackled the latter challenge by masking one source (e.g., ICD10 codes) and training the transformer to pre

Multiple language learning has been largely neglected in L2 motivation research. Recently, complexity principles have been used to model multilingual motivation. In this work, multilingual self-guides are conceptualised as emergent from interactions between the motivation systems of different languages. Motivational systems and their emergent properties are also influenced by the contexts in which

Learning a language is a long-term undertaking. In this endeavor, motivation is served by patterns of regulation that steer and control behavior. Regulation can be focused on possibilities and opportunities (an approach pattern), or the implications of failure (an avoidance pattern). Responding to calls for work with a focus on regulation (Papi et al., 2019), and with the aim of developing insight

Demotivation (Dörnyei & Ushioda, 2011) and non-participation (Norton, 2001) characterise negative responses to classroom practice of a generally chronic nature. In this article, focus is directed to negativity that emerges within the context of a particular language developing activity, and which can be understood as a situated response to the activity's demands. In conceptualizing negative re

Antalet subventionerade jobb har växt samtidigt som andelen utrikes födda bidragsanställda ökat och andelen funktionsnedsatta minskat. Anställningsbidragen är särskilt frekventa i handels-, restaurang-, städ- och bemanningsbranscherna. I föreliggande studie har samtliga nya anställningsbidrag 2016 i de fyra branscherna i Helsingborg undersökts. En tydlig etnisk segmentering påvisas genom att en be

The polygenic background of selectively bred diabetes models mimics the etiology of type 2 diabetes. So far, three different rodent models (Goto-Kakizaki rats, Nagoya-Shibata-Yasuda mice, and Oikawa-Nagao mice) have been established in the diabetes research field by continuous selective breeding for glucose tolerance from outbred rodent stocks. The origin of hyperglycemia in these rodents is mainl

The ability to store and mobilize energy is fundamental for physiologic function. Most excess energy is stored in adipose tissue as triglycerides, which is released as free fatty acids when needed through cellular processes tightly regulated by insulin. Intact adipose cell function is essential to regulate whole-body glucose and lipid metabolism. Several studies have focused on the metabolic impac

Project funding rarely demands much change on behalf of the recipient. In contrast, cross-sectoral mobility funding requires recipients to change their environment and often some aspects of their research. There is a need to understand the impact on the researchers’ experiences as knowledge producers within such programs, as part of the broader potential and significance of cross-sectoral mobility

High sound levels related to medical equipment and high activity day and night, is a wellknown phenomenon in intensive care units (ICUs). This may result in poor sleep and prolonged recovery for the patients but may also be a precipitating factor for intensive care delirium (ICU delirium).The aim of this pilot study was to describe patients' responses to the sound environment in an ICU and to iden

How can we govern consumption and the sharing economy in our cities? This course explores cities, consumption and the sharing economy in Europe and around the world. We connect together the key themes of the sharing economy, cities, governance, consumption and urban sustainability. We explore how the sharing economy can contribute to increasing social, environmental and economic sustainability. An