Kluth et al. identify a significant enrichment of cilia-annotated genes that are differentially expressed in pancreatic islets of obese mice. Many of the genes were also linked to human T2D, suggesting that dysregulation of cilia-associated genes may participate in T2D risk.

Purpose: Preoperative chemotherapy is underused in conjunction with radical cystectomy (RC) for muscle-invasive bladder cancer (MIBC) due to concerns for complications and delay of surgery. Prospective data on short-term complications from population-based settings with frequent use of preoperative chemotherapy and standardised reporting of complications is lacking. Methods: We identified 1,340 pa

Objectives: Counts of missing teeth or measures of incident tooth loss are gaining attention as a simple way to measure dental status in large population studies. We explore the meaning of these metrics and how missing teeth might influence other measures of dental status. Methods: An observational study was performed in 2 contrasting adult populations. In total, 62 522 adult participants were ava

Political comedy in various forms is increasingly popular among media audiences, directing scholarly attention to issues like shifting news habits and values, and further, potential impacts on civic cultures. But with the exception of media effects studies, audiences of political com-edy remain largely under-researched (Marchi 2012; Jones 2013).This paper deals with young adult audiences of politi

Reduction of energy use constitutes as an important measure for climate change mitigation. Buildings today account for 40% of the world’s primary energy use and 24% of the greenhouse gas emissions [International Energy Agency (IEA) 2011]0. The concept of passive houses is one of many necessary measures for climate change mitigation. To reach the passive house ambition in cold climates, increased t

In research on Birka strong focus has since long been directed towards long-distance contacts with Western as well with and Northeastern Europe (todays Russia, Belarus and Ukraine). The great attention paid to west- and east European contacts has likely contributed to that contacts with Finland have fallen out of the discussions. However as seen from studies of the pottery in Birka the Baltic Finn

Nordic noir is an emerging crime genre that draws on crime fiction, feature film, and television drama. The term Nordic noir is associated with a region (Scandinavia), with a mood (gloomy and bleak), with a look (dark and grim), and with strong characters and a compelling narrative. Such is the popularity of Nordic noir as a brand for crime that it can also, and somewhat confusingly, be associated

BACKGROUND: The 65-kD isoform of glutamic acid decarboxylase (GAD65) is a major autoantigen in type 1 diabetes. We hypothesized that alum-formulated GAD65 (GAD-alum) can preserve beta-cell function in patients with recent-onset type 1 diabetes. METHODS: We studied 334 patients, 10 to 20 years of age, with type 1 diabetes, fasting C-peptide levels of more than 0.3 ng per milliliter (0.1 nmol per li

This paper deals with those provisions of the new EU Regulation No. 2015/848 on Insolvency Proceedings (Recast) that create a system of national insolvency registers and establish a decentralized system for the interconnection of such registers by means of the European e-Justice Portal.