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OBJECTIVE:: Caesarean section (C-section) is associated with various immune-mediated diseases in the offspring. We investigated the relationship between mode of delivery and celiac disease (CD) and CD autoimmunity (CDA) in a multinational birth cohort. METHODS:: From 2004 to 2010 infants from the general population who tested positive for HLA DR3-DQ2 or DR4-DQ8 were enrolled in The Environmental D
BACKGROUND: It is estimated that global dementia rates will more than triple by 2050 and result in a staggering economic burden on families and societies. Dementia carries significant physical, psychological and social challenges for individuals and caregivers. Informal caregiving is common and increasing as more people with dementia are being cared for at home instead of in nursing homes. Caregiv
Carotid intima-media thickness (IMT) is a measure of arterial thickening and a risk predictor for myocardial infarction and stroke. It is unclear whether IMT also predicts atrial fibrillation (AF). We explored the association between IMT and incidence of first AF hospitalization in a population-based cohort.
Background: Dihydrotestosterone (DHT), the most potent ligand to the androgen receptor, is synthesised from testosterone (T) by 5α-reductase type 1 and 2. While type 1 is expressed in several non-reproductive tissues in both sexes, men also express high levels of the high-affinity type 2 isoform in reproductive tissues; yet women have a higher circulating DHT to T (DHT/T) ratio than men. We hypoth
Purpose: The Paleolithic Diet Fraction (PDF) estimates the proportion of absolute dietary intake derived from food groups included in the Paleolithic diet. In the Malmö Diet and Cancer Study (MDCS), higher PDF and lower systemic low-grade chronic inflammation (SLGCI) have been associated with lower cardiometabolic morbidity and mortality. We examined associations between PDF and SLGCI in the MDCS.
Objective: Worse women's outcomes after elective standard endovascular aneurysm repair have been widely reported. Similar data have surfaced from cohorts undergoing fenestrated and branched repair; however, studies reporting from a sex perspective are rare and mostly limited to single centre designs. This study aimed to examine survival following nationwide complex endovascular repair according to
Background and Aims: Colon capsule endoscopy (CCE) provides a non-invasive alternative to traditional colonoscopy. This study evaluated the feasibility, safety, diagnostic yield (DY), and patient satisfaction of the OMOM CC100 CCE system, with special focus on fully remote (n = 30) and partially remote (n = 89) administration across four centres to advance decentralised models. Methods: This prosp
Idag lever allt fler människor under förhållanden som definieras som prekära. Även i avancerade välfärdssamhällen lyckas inte de traditionella trygghetssystemen erkänna och hantera de nya sociala risker som dessa grupper inom ”prekariatet” ställs inför. Bland dessa grupper finner vi migrantkvinnor med osäker rättslig ställning. Denna forskning undersöker hur aktörer i akademin och i civilsamhälletIn advanced welfare societies, traditional welfare programs are failing to recognize and respond to new social risks faced by groups in precarious life situations, including migrant women. This research explore how actors in academic and civil society settings recognize and frame the struggles of migrant women with precarious legal status, particularly in terms of gender-based violence (GBV) and a
Background: Aortic valve calcification (AVC) is an underlying pathophysiological mechanism in aortic stenosis, which shares many risk factors with diabetes. However, the association between dysglycemia and early stages of AVC remains unclear. The aim was to examine the associations between stages of dysglycemia and signs of AVC among middle-aged individuals from the general population. Methods: Th
