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PROTEIN VACCINE AGAINST NEONATAL GROUP B STREPTOCOCCAL INFECTION Immunization experiments in animals and a serological study in humans

Infection with group B streptococcus (GBS), an encapsulated bacterium, is an important cause of neonatal morbidity and mortality. Capsular polysaccharides and cell surface proteins of GBS are candidate antigens for development of a human GBS vaccine. Proteins have many advantages as vaccine antigens. The majority of the neonatal infections are caused by strains of capsular serotypes Ia, Ib, II, II

Learning to Take Risks? The Effect of Education on Risk-Taking in Financial Markets

We investigate whether acquiring more education when young has long-term effects on risk-taking behavior in financial markets and whether the effects spill over to spouses and children. There is substantial evidence that more educated people are more likely to invest in the stock market. However, little is known about whether this is a causal effect of education or whether it arises from the corre

Violaxanthin De-epoxidase and the Xanthophyll Cycle

The xanthophyll cycle is a mechanism for short term adaptation of plants to varying light intensities. It involves a reversible conversion of violaxanthin to zeaxanthin, via the intermediate antheraxanthin, upon high light intensities. This conversion is catalyzed by violaxanthin de-epoxidase (VDE) and the product after de-epoxidation, zeaxanthin, is involved in non-photochemical quenching of exce

Bostadskultur, informationsflöden och hantverkare 1740-1820 med utgångspunkt i Bålby (Närke) och Skottsbergska gården (Blekinge)

The thesis Housing Culture, Information Flows, and Craftsmen 1740-1820 (Bostadskultur, informationsflöden och hantverkare 1740-1820) investigates two mansion houses – Bålby in Närke and Skottsbergska gården in Karlshamn – with the focus on craftsmen and their clients. This is in order to analyse the relationship between professional craftsmen in the capital and in other regions. The clients have a

Genital human papillomaviruses. Studies of their occurrence, type spectrum and expression.

The occurrence of genital human papillomavirus infection was determined in different categories of patients by means of PCR. In high proportion of young women attending an adolescent clinic, the presence of HPV DNA was demonstrated in simultaneously urethral and cervical samples, suggesting that genital HPV infections are often multifocal. Multiple HPV types were demonstrated in about half of the

Characterization and Clinical Application of Normoxic Polymer Gel in Radiation Therapy Dosimetry

Cancer is one of the main causes of death in the world, particularly in developing countries and is considered as a major public health problem. Radiation therapy has been an important modality for treatment of cancer for many decades. It can be used as a sole treatment modality or in combination with for example surgery, chemotherapy, hormone therapy and/or immune therapy. It has been calculated

Dynamics Within and Outside the Lab. Procedings from the 6th GRASP conference, Lund University, May 2008

Since May 1998 Scandinavian group researchers and social psychologists have met bi-annually for what has to be called the GRASP conference. GRASP originally stood for ”Group as Paradox”. The first five conferences were held in Linköping, Lund, Stockholm and Skövde and, again, Linköping. The sixth conference was organized at Lund University May 15-16, 2008 under the auspices of the network Organi

Emulsion formation and stability - Impact of the dispersed state of the emulsifier on emulsification

Emulsions find a variety of applications in for example food, cosmetics and pharmaceutical preparations. In order to obtain emulsions with desired properties it is important to understand how different factors, such as the properties of the emulsifier and the emulsification procedure, impact the final emulsion properties. The studies performed in relation to this thesis have mainly been focused

Foodborne Virulence: Staphylococcus aureus Enterotoxins A and D

The development of new, minimally processed food products challenges traditional concepts of food safety. How pathogenic bacteria behave in these new matrices is not known. To fill this knowledge gap and enable the production of food that is safe for the consumer, more information on virulence expression of pathogens in food matrices is required. In this thesis, the impact of environmental factors

Effect of water contamination on the diffused content of hydrogen under stress in AISI-52100 bearing steel

Abstract Hydrogen embrittlement is a degradation process of mechanical/tribological properties (toughness, wear etc.) of mating steel surfaces. This is caused by the presence and interaction of hydrogen with applied stresses. Therefore, it is important to quantify the hydrogen content which could be dissolved under applied stresses in steel. Water contamination of lubricants is often considered as

Mechanisms of Growth Hormone Signal Transduction - Studies on the insulin-like metabolic effects in primary rat adipocytes

Growth hormone (GH) exerts growth-promoting and metabolic effects in mammals. The metabolic effects of GH in adipose tissue are insulin-antagonistic or insulin-like. Cells that just have been exposed to GH are insensitive to the hormone. This study addresses the question of how GH exerts its insulin-like metabolic effects, using primary rat adipocytes as a model system. It is shown that GH increas