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untitled Human foetal brain tissue as quality control when developing stem cells towards cell replacement therapy for neurological diseases Jenny Nelander, Shane Grealish and Malin Parmar Human foetal brain tissue has been used in experimental and clinical trials to develop cell replacement therapy in neurodegenerative disorders such as Parkinson’s disease and Huntington’s disease. These pioneerin
The association between stressful life events and respiratory infections during the first 4 years of life: The Environmental Determinants of Diabetes in the Young study Received: 4 April 2018 Revised: 6 February 2019 Accepted: 7 February 2019 DOI: 10.1002/smi.2861 R E S E A R CH AR T I C L E The association between stressful life events and respiratory infections during the first 4 years of life:
https://www.teddy.lu.se/sites/teddy.lu.se/files/2021-12/104%2005072019_679_104_MP30_Roth_Stress%20Health_2019.pdf - 2026-05-09
There is huge potential to increase installation of photovoltaics (PV) using the roofs of non-residential buildings. While barriers to and enablers of the adoption of PV in residential buildings are well studied, this is not the case for non-residential buildings. This article is intended to fill this research gap by mapping barriers to and enablers of PV adoption by property owners of non-residen
OBJECTIVE: To externally validate the Paediatric Emergency Care Applied Research Network (PECARN) rule for identifying febrile infants aged <60 days at low risk of serious bacterial infections (SBIs) and assess the utility of the rule with C reactive protein (CRP) instead of procalcitonin (PCT).METHODS: Secondary analysis of data from the Management and Outcomes of Fever in Children in Europe (MOF
The on-site documentation and examination of architectural heritage has presented challenges for traditional analysis methods in the form of, among other things, large complex structures, sites and environmental conditions. In recent years there has been growing interest in assessing progressing deterioration processes and material analysis, with an emphasis on sustainable conservation and mainten
Defective insulin secretion and insulin resistance are the two hallmarks of Type 2 Diabetes (T2D). The pathophysiology of the disease is not fully understood but genetic susceptibility for the disease is a new major player in the understanding of the underlying mechanisms. T2D research has in recent years invested tremendous efforts in identifying new risk variants for the disease. It has proven t
Background and Aims: Differences in the clinical care of patients have been explained through the concept of practice variation, that is, the occurrence of established local medical procedures that varies between geographic areas. The primary measures introduced to eliminate undesirable differences in medical care are the introduction of medical guidelines and economical incentives that rewards th
The incidence of diabetes is increasing worldwide, with the most prevalent form being type 2 diabetes. Two fundamental processes contribute to the development of type 2 diabetes: insulin resistance in target organs and insufficient insulin secretion from the pancreatic beta-cells. The aim of this thesis was to explore the role of DNA methylation and common genetic variation on glucose metabolism a
Atherosclerosis is a chronic inflammatory disease characterized by the formation of lipid rich plaques in the arterial wall. Rupture of a plaque results in clinical manifestations such myocardial infarction or stroke. Atherosclerosis is a complex disease where both autoimmune responses towards atherosclerosis-related antigens and smooth muscle repair responses play important roles. This thesis con
One of the great challenges in breast cancer treatment today is to customize adjuvant treatment to each patient’s individual needs. To do this it is necessary to learn more about the prognostic and treatment predictive factors that determine the risk of relapse and response to a certain mode of treatment. This thesis describes studies on the effect of amplified in breast cancer 1 (AIB1), a coactiv
