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Tumour deposits are a prognostic factor for overall survival and distant metastasis in lymph node-negative colorectal cancer. However, the current TNM staging system does not account for the presence of tumour deposits in lymph node-positive colorectal cancer, or for the presence of multiple deposits. This study aimed to investigate the prognostic effect of tumour deposit count in patients with coBackgroundTumour deposits are a prognostic factor for overall survival and distant metastasis in lymph node-negative colorectal cancer. However, the current TNM staging system does not account for the presence of tumour deposits in lymph node-positive colorectal cancer, or for the presence of multiple deposits. This study aimed to investigate the prognostic effect of tumour deposit count in patien

AbstractThe cycling of carbon in its gaseous, solid and dissolved forms is of central importance to ecosystem science, particularly, when the natural carbon cycle has been perturbed by human activity. Mathematical models are commonly used to asses and predict global and regional patterns of terrestrial carbon exchange. At the same time, processes operating on smaller (sub-grid) scales are usually

Meniscectomy is recognized as an important risk factor for the development of knee osteoarthritis (OA), a disease that traditionally has been considered as a simple "wear and tear" phenomenon. However, despite numerous reports, little evidence has been presented that a limited meniscal resection, compared with a more extensive resection, reduces the risk of OA by preserving meniscal function. Why?

The aim of this thesis was to investigate how older people's capacity to perform activities of daily living (ADL), health, social and financial resources, and self-esteem can be related to their life satisfaction. The aim was also to investigate how people feel hindered by health problems in relation to their ADL capacity, health problems, social and financial resources, self-esteem, sense of cohe

Most animals will encounter several more or less severe infectious diseases during their lifetime, and simultaneous infections with more than one pathogen, or several different strains of the same pathogen, are common in natural populations. Ticks transmit a wide variety of different pathogens and can also be simultaneously infected with more than one pathogen. The possible interactions between di

To examine cardiovascular disease risk factors, control of hypertension and survival in patients with hypertension treated in primary care, patients with hypertension and/or type 2 diabetes were surveyed for cardiovascular disease risk factors and treatment 1992-1993. For reference, a random population sample from the same community was surveyed 1993-1994. During 1998, antihypertensive prescriptio

Case-control studies comprising telephone interviews for 333 cases of acute myeloid leukemia (AML), 226 cases of Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML), 330 cases of myelodysplastic syndromes (MDS), and matched controls were conducted. Information had to be obtained from next-of-kin much more often for cases (85%) than for controls (18%). Tobacco smoking was associated

Energy use in buildings accounts for a significant proportion of the total energy use in many countries. While past and current buildings have solely been energy consumers, future buildings will, besides using less energy, also need to produce (part of ) the required energy on site with renewables. Solar energy is generally very suitable for producing this on-site renewable energy. Although solar

The effects of increasing temperatures, in light of climate change, have been a well-studied topic during the past decades. However, aquatic ecosystems are also faced with additional challenges such as increasing water colour, known as “brownification”. Although we know that temperature and water colour will increase simultaneously this has been given little attention in ecological research. In th

The shore protection has in Sweden been statutory regulated since 1950. Since then it has been extended and developed, as the awareness of the importance for preservation of unexploited land along the shores has grown. The earlier legislation focused entirely on human’s access to the shores and the surroundings near the shores, for recreation and extracurricular activities. The terms for, and pres

Helicobacter pylori is one of the most common infections in man. The infection is often acquired during childhood and usually results in a chronic life-long inflammation in the gastric mucosa. The aim of our studies was to investigate the association between H. pylori seropositivity and the development of gastric and oesophageal carcinomas. Nested case-control studies were performed in the Malmö P

Obesity is one of the major health concerns that has reached epidemic proportions globally. It is generally believed to be a result of interactions between genetic and environmental factors. In this thesis we investigated the role of dietary factors in modifying the genetic susceptibility to obesity (papers I to III), studied the association between genetic susceptibility to obesity and weight gai

Osteoporosis and related fractures are a global health problem. Physical activity, especially during growth, has been suggested as a strategy to improve musculoskeletal health in the population. Previous prospective pediatric exercise intervention studies, however, are short-term, mostly covering less than one year and use bone traits as surrogate endpoints for fractures. The Pediatric Osteoporosi

https://www.regenerative-neurobiology.lu.se/sites/regenerative-neurobiology.lu.se/files/andersson_et_al_exp_cell_res_2007.pdf - 2026-05-07

https://www.nateko.lu.se/sv/sites/nateko.lu.se.sv/files/nitin-kappa.pdf - 2026-05-07

The ice age is coming, the sun is zooming in, Engines stop running and the wheat is growing thin, A nuclear error, but I have no fear, London is drowning and I live by the river…… (Jones/Strummer 1977) Past climates Mats Rundgren Department of Geology Quaternary Sciences Lund University with contributions by Ian Snowball NGEN03 2016 Lecture content • Earth’s climate system • External climate forci

https://www.nateko.lu.se/sites/nateko.lu.se/files/ngen03_snowball_rundgren_2016_1.pdf - 2026-05-07

https://www.nateko.lu.se/sv/sites/nateko.lu.se.sv/files/kappa.pdf - 2026-05-07

Genetic and Environmental Interactions Modify the Risk of Diabetes-Related Autoimmunity by 6 Years of Age: The TEDDY Study Genetic and Environmental Interactions Modify the Risk of Diabetes-Related Autoimmunity by 6 Years of Age: The TEDDY Study https://doi.org/10.2337/dc17-0238 OBJECTIVE Wetested the associations between genetic backgroundand selected environmental exposures with respect to islet

https://www.teddy.lu.se/sites/teddy.lu.se/files/03022018_679_70_mp45_krischer_diab_care_2017.pdf - 2026-05-07

pedi_774.dvi Pediatric Diabetes 2011 doi: 10.1111/j.1399-5448.2011.00774.x All rights reserved © 2011 John Wiley & Sons A/S Pediatric Diabetes Original Article The Environmental Determinants of Diabetes in the Young (TEDDY): genetic criteria and international diabetes risk screening of 421 000 infants Hagopian WA, Erlich H, Lernmark Å, Rewers M, Ziegler AG, Simell O, Akolkar B, Vogt Jr R, Blair A

https://www.teddy.lu.se/sites/teddy.lu.se/files/06032016_679_13_hagopian_ped_diab_2011.pdf - 2026-05-07