Filtyp
Surrogatmoderskap är en metod för att bli förälder som är oreglerad både inom svensk och internationell rätt. I praktiken är det dock omöjligt att ge- nomföra ett surrogatarrangemang inom den svenska sjukvården. Däremot kan man som svensk anlita en surrogatmoder utomlands med hjälp av en surroga- tagentur. Sådana förfaranden har länge varit föremål för debatt och flera fall av exploatering av både
Inom det senaste decenniet har marknadsföring spridit sig till ett brett spektrum av medier. Däribland marknadsföringsåtgärder som förekommer på internet. Sådan marknadsföring faller under olika tillämpliga bestämmelser beroende på vilken konsumentgrupp eller land som verksamheten riktar sin marknadsföring mot och även vilket land som verksamheten är etablerad i. Den svenska marknadsföringslagen
When anti-epileptic drugs fail, and epilepsy surgery is found unfeasible or ineffective, there remains a group of at least 25% of children with epilepsy in whom seizure control cannot be achieved. Vagus nerve stimulation (VNS) is an adjunctive treatment for medically refractory epilepsy. It is an implantable, multi-programmable pulse generator that delivers current electrical stimulation to the va
The vascular wall has a remarkable capacity to adapt to mechanical forces exerted by the intraluminal blood pressure and flow. This includes rapid change in contractile tone as well as chronic alteration of vessel structure if the stimulus persists. Stretch of the intact blood vessel wall promotes growth and contractile differentiation. The molecular mechanisms involved are not well defined, but c
Light detection and ranging (lidar), a method for nonintrusive, single-ended, and range resolved measurements, has been developed and applied for combustion related diagnostics. Employing picosecond laser pulse durations and detectors providing temporal resolution on the order of picoseconds, lidar has been applied successfully for both quantitative temperature- and species concentration measureme
This thesis presents experimental studies of microchannel acoustophoresis, a technique for manipulation of microscopic objects in suspension by means of acoustic radiation forces induced by ultrasonic standing wave fields. By arranging an acoustic resonance across the width of a microchannel, the path of individual cells or microparticles can be deflected orthogonally to the fluid flow. The prop
Type 2 diabetes and the metabolic syndrome are highly prevalent disorders with severe complications such as cardiovascular disease. The aetiology of type 2 diabetes and the metabolic syndrome is not known, but the interaction between genetic factors and environmental triggers is important. The aim this thesis was to identify genetic factors that may increase susceptibility to these disorders by in
Epithelial damage may contribute to the pathology in airway diseases such as asthma and rhinitis. However, the distribution of epithelial shedding in inflammatory airway diseases and, particularly, the ensuing repair processes are largely unknown. In the present studies we have developed novel in vivo techniques to explore epithelial repair mechanisms and associated tissue responses occuring in gu
Eta Carinae is a super-massive, super-luminous star. It is surrounded by a bipolar nebula, the "Homunculus", and several blobs of ejected gas which are the source of a complex emission-line spectrum. This thesis presents results from spectroscopic investigations of the star and its surroundings, performed with the Space Telescope Imaging Spectrograph (STIS) and the Goddard High Resolution Spectrog
Eta Carinae is one of the most massive and luminous stars in the Galaxy. A huge bipolar nebula and an equatorial disk give the object a characteristic shape. Close to the star there are gas clouds, which emit intriguing emission line spectra. One such region, the strontium filament, is studied in more detail in this thesis, and the identities of 600 emission lines are reported. Some of these requi
Highly glycosylated glycoproteins – mucins – are the major constituents of the mucus layer and glycocalyx that cover mucosal surfaces. Twelve human mucin genes have been identified, and the mucins may be divided into those that are membraneassociated and those that are secreted. Among the latter, the oligomeric mucins are responsible for mucus formation. The various tissues have characteristic muc
The potato is one of our most important food crops, being sold in its natural state or processed into a wide range of products. Starch, by far the most abundant component in the tuber, is greatly affected by heat processing. Therefore it is logical to study starch thermal properties within the tuber tissue, although most previous studies have focused on starch-water model systems. One of the main
The release of urokinase plasminogen activator (uPA) from endometrial stromal cells decreased after progesterone stimulation, due to upregulation of PA inhibitor 1 (PAI-1) and uPA receptor (uPAR). Subsequently, the uPA:PAI-1 complex was internalized and degraded via uPAR. Predecidual cells in the late secretory phase expressed PAI-1 and uPAR, supporting a specific role for predecidual cells in the
Dermatan sulphate is a prominent feature of several different proteoglycans and occurs in almost every tissue of the body. It is an unbranched polymer containing the repeating disaccharide unit of N-acetylgalactosamine and D-glucuronic acid or L-iduronic acid. The polymer can be highly sulphated resulting in an unusual and largely unknown diversity in the chain. The unique step in dermatan sulphat
The incidence of sexual selection in plants is today acknowledged, however, just as in animals, evolution and maintenance of mate choice is gravely underexplored. Moreover, the potential for sexual conflicts to occur in plants has only been assessed empirically to a very limited degree. Using the hermaphroditic annual herb Collinsia heterophylla, I looked deeper into the role of pollen-pollen comp
Eosinophils are multi-functional leukocytes involved in the pathophysiology of inflammatory diseases such as asthma and inflammatory bowel disease. Participation in some neoplastic diseases and in the host defense against helminths has also been postulated. They are considered both good and bad, protecting or harming the host. The exact roles of eosinophils and their mechanisms of action are poorl
