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Neuropathological changes in Parkinson's disease progress slowly and spread according to a characteristic pattern. Recent papers have shed light on this progression of pathology by examining the fate of neurons grafted into the brains of patients with Parkinson's disease. Two of these studies demonstrate that grafted healthy neurons can gradually develop the same pathology as host neurons in the d
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This paper introduces the use of co-nomination as a method to map research fields by directly accessing their knowledge networks organised around exchange relationships of intellectual influence. Co-nomination is a reputation-based approach combining snowball sampling and social network analysis. It compliments established bibliometric mapping methods by addressing some of their typical shortcomin
Importance: Human genetics and studies in experimental models support a key role of monocyte-chemoattractant protein-1 (MCP-1) in atherosclerosis. Yet, the associations of circulating MCP-1 levels with risk of coronary heart disease and cardiovascular death in the general population remain largely unexplored. Objective: To explore whether circulating levels of MCP-1 are associated with risk of inc
The Global Hyperorgan is an intercontinental, creative space for acoustic musicking. Existing pipe organs around the world are networked for real-time, geographicallydistant performance, with performers utilizing instruments and other input devices to collaborate musically through the voices of the pipes in each location. A pilot study was carried out in January 2021, connecting two large pipe org
European Americans are often treated as a homogeneous group, but in fact form a structured population due to historical immigration of diverse source populations. Discerning the ancestry of European Americans genotyped in association studies is important in order to prevent false-positive or false-negative associations due to population stratification and to identify genetic variants whose contrib
From its inception, leadership studies has embraced the positivist tradition of hypothesis testing. In this tradition, psychometric instruments are meant to ward off belief from scientific practice by testing theories against empirical facts. While leadership scholars purport to conform to the standards of value-neutral science, this paper tells a different story. Drawing on qualitative interviews
Direct electrochemical measurements of glutamate release in vivo were combined with optogenetics in order to examine light-induced control of glutamate neurotransmission in the rodent brain. Self-referenced recordings of glutamate using ceramic-based microelectrode arrays (MEAs) in hippocampus and frontal cortex demonstrated precise optical control of light-induced glutamate release through channe
Empowerment has been a key conceptual underpinning of participatory health research (PHR), both as a set of processes that inform how partners and diverse stakeholders engage with each other, as well as a set of outcomes that contribute to improved health and social equity. The concept of empowerment is present in a number of characteristics of PHR as described in Position Paper No. 1 of the ICPHR
Structured illumination is an imaging method most commonly employed within the field of microscopy. However, recently the technique has spread into other scientific fields, such as for combustion research, where it has revealed new measurement opportunities. This paper describes how structured illumination can be employed for spray- and combustion research and highlights some of the recent progres
Crocodilians are the closest living relatives of birds and share many ecological challenges with mammalian apex predators. They evolved perception pathways that share similarities with both taxa, birds and mammals. Due to their position in the tree of life, crocodilians therefore represent a promising intermediate model for comparative research. In this review, the different modalities of percepti
Eight patients with primary hypothyroidism were compared to eleven euthyroid subjects with regard to the effects of a single i.v. dose of heparin on plasma lipoprotein concentrations (the "clearing reaction"). The hypothyroid patients were moderately hypercholesterolemic but had normal plasma triglyceride levels. Maximal activities of hepatic lipase (HL) and lipoprotein lipase (LPL) were lower in
