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Background: Adult-onset diabetes comprises subgroups differing in pathophysiology, clinical presentation, and risk of comorbidities. We investigated early phenotypic differences between individuals who later developed diabetes, stratified by subgroup at diabetes diagnosis. Methods: We conducted a pooled analysis of nine prospective European cohorts with 3309 individuals developing incident diabete
Academic research increasingly focuses on environmental sustainability as a specific societal mission to be addressed. However, the effects of the increasing sustainability orientation on output generation in public research organizations are largely unexplored. In this paper, we analyse the effects of the increasing importance of sustainability-oriented research topics on research and teaching ef
Neoliberalism, as a loosely defined set of political beliefs, calls for more individual freedom and autonomy, resulting in increased responsibility for each person to address major societal issues. ‘Individualization’ is the process by which responsibility for addressing major environmental issues such as climate change is placed on individuals. In this thesis I investigate whether individualizati
To dissect the genetic architecture of blood pressure and assess effects on target organ damage, we analyzed 128,272 SNPs from targeted and genome-wide arrays in 201,529 individuals of European ancestry, and genotypes from an additional 140,886 individuals were used for validation. We identified 66 blood pressure-associated loci, of which 17 were new; 15 harbored multiple distinct association sign
BackgroundFunctional MRI (fMRI) is a non-invasive technique for the study of brain function that utilizes changes in blood flow and volume accompanying brain activation. When neuronal activation occurs, local blood flow increases, leading to an increase in oxygenated blood. The different magnetic properties of oxygenated and deoxygenated blood yields signal changes in the MRI images. This effect i
https://www.msf.lu.se/research/mr-physics-group/research-environments/fmri - 2026-10-01
BACKGROUND: Mood disorders and strokes are often comorbid, and their health toll worldwide is huge. This study characterizes prognostic and causal roles of mood disorders in stroke.METHODS: We tested if genetic susceptibilities for mood disorders were associated with all strokes, ischemic strokes in the Malmö Diet and Cancer cohort (24 631 individuals with a median follow-up of 21.3 (interquartile
The Chinese stock market has been established for more than 20 years. Although it is not as mature as the highly developed western securities markets, it has a huge influence on the global economy. It is significant to study the risks of the Chinese stock market, especially the risk of stock indexes. Affected by the economic globalization today, more and more financial derivatives and financial i
Bilateral aid agencies often face implementation challenges in internal efforts to address long-standing aid fragmentation and effectiveness issues. This article introduces the organisational identity concept to understand better these challenges by examining how Swedish International Development Cooperation Agency (Sida) frontline staff understand their role and organisational goals in light of s
De senaste teknologiska framstegen har lett till skapandet av högspecialiserade system inom olika industrier, vilket möjliggör uppgifter som tidigare varit otänkbara. I takt med att den globala efterfrågan på hållbara och effektiva energilösningar ökar, har behovet av innovation inom teknik aldrig varit större. Dessa framsteg representerar transformativa förändringar som omformar hela sektorer. FrRecent technological advancements have led to the creation of highly specialized systems across various industries, enabling tasks that were once beyond imagination. As the global demand for sustainable and efficient energy solutions grows, the urgency for innovation in technology has never been greater. These advancements are not simply incremental but represent transformative changes that are re
Structured illumination is an imaging method most commonly employed within the field of microscopy. However, recently the technique has spread into other scientific fields, such as for combustion research, where it has revealed new measurement opportunities. This paper describes how structured illumination can be employed for spray- and combustion research and highlights some of the recent progres
BACKGROUND: The balance between stabilizing and destabilizing atherosclerotic plaque components is used in experimental studies and in imaging studies to identify rupture prone plaques. However, we lack the evidence that this balance predicts future cardiovascular events. Here we explore whether a calculated histological ratio, referred to as vulnerability index (VI), can predict patients at highe
The sharing economy emerged in the last decade as an innovative business model in response to economic fallout, societal distress, and surging awareness over the devastating effects of the climate crisis. It pledges to repudiate mass consumption in favour of a democratization of access to common resources. This thesis seeks to dissect how the Japanese government has employed the sharing economy––a
The tourism sector declared a climate emergency in 2020. It is against this background that this Curated Collection on Climate Change and Tourism is launched. A bibliometric analysis of 1290 articles reviews the 35-year development of climate change and tourism scholarship, including major research themes, key knowledge gaps, and our capacity to deliver the enormous knowledge requirements for an e
Aim: To value the importance of research on avian migration for the development and current status of Spanish ornithology. Results and Conclusions: Avian migration has always been an outstanding field in ornithology. This assertion is particularly true in Spain, as we illustrate here by discussing the contribution of migration research to both the scientific and historical development of Spanish o
Stem cell-based approaches hold much promise as potential novel treatments to restore function after stroke. Studies in animal models have shown that stem cell transplantation can improve function by replacing neurons or by trophic actions, modulation of inflammation, promotion of angiogenesis, remyelination and axonal plasticity, and neuroprotection. Endogenous neural stem cells are also potentia
OBJECTIVES: To determine whether a long-term treatment with beta-blockers influences the inflammatory activity in carotid artery disease by reducing the carotid plaque levels of lipoprotein-associated phospholipase A2 (Lp-PLA2), its enzymatic products lysophosphatidylcholine (lysoPCs), and of soluble urokinase plasminogen activator receptor (suPAR). MATERIALS AND METHODS: One hundred and thirty-fo
