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The purpose of this study was to investigate the prevalence of toxic agents in attempted and completed suicides. The purpose was also to explore the sources of the drugs taken by suicide attempters. Verbal information on drug intake was collected from 280 suicide attempters during 1987-1990 in the Lund-Orup catchment area. Information on the sources of the drugs was collected from 143 of these att
Popular Abstract in Swedish Korsningsintensiteten for en stationär stokastisk process är ett värdefullt verktyg när man studerar fördelningen för våghöjder och för maxima av havsnivån. Denna avhandling betraktar två approximationstekniker för fall då korsningsintensiteten inte kan ges exakt.Båda tekniker använder en asymptotisk expansion, och första och andra ordningens termer i denna approximatioThe crossing rate of a stationary random process is a valuble tool when studying crest hight distributions and maxima of sea level elevation. This thesis considers two approximation techinques for cases when the crossing rate cannot be exactly computed. Both techniques use an asymptotic expansion, and the first and second order terms in these expansions are given explicitly. Paper A describes how
Popular Abstract in Swedish Autoimmuna sjukdomar såsom reumatoid artrit (RA) och multipel skleros (MS) uppkommer av en felaktig immunrespons mot kroppens egen vävnad. Orsaken är okänd trots enormt mycket forskning om ämnet. Ett sätt att öka kunskapen vore att identifiera de gener som bidrar till sjukdomarna. För sådana relativt vanliga, komplexa sjukdomar finns det inte en gen som ?styr? sjukdomarAutoimmune diseases are dependent on both genetic and environmental factors in complex interplay. They arise from a faulty immune response against self-antigens, and causes great suffering in affected individuals. Despite large efforts and hundreds of thousands of research articles published, the disease etiologies remain largely unknown. Knowledge of which genes are involved and how they interact
Introduction: Transnationalism and migration Ulf Johansson Dahre The 5th annual Somalia International Rehabilitation Centre (SIRC) Conference of the Horn of Africa focused on “The Role of Diasporas in Peace, Democracy and Development”. The conference was held in Lund, Sweden, August 19-20, 2006. The content of this volume reflects some of the views and proceedings presented at the conference. I
In the developed countries the public expect society to be prepared for, and step in, if something out of the ordinary happens. This public pressure appears to have increased the demand for crisis preparedness planning. In crisis management the local authority serves as the first line of defence and will more or less always be involved in responding to crises. It is therefore important to study ho
Purpose of this paper The purpose of this paper is to present a comparative case study of the procedures and guiding principles in the packaging selection practice of two international companies. Design/methodology/approach A qualitative case study with an inductive approach was conducted. The data was collected through semi-structured interviews, documentation, and field visits. Findings Th
The objective of this paper is to demonstrate the full-scale feasibility of the phenomenological dynamic influent pollutant disturbance scenario generator (DIPDSG) that was originally used to create the influent data of the International Water Association (IWA) Benchmark Simulation Model No. 2 (BSM2). In this study, the influent characteristics of two large Scandinavian treatment facilities are st
We have recently shown that negative pressure wound therapy (NPWT) induces a decrease in microvascular blood flow in the small intestinal loop close to the dressing. The effect of NPWT is thus thought to be local. In this study, we investigate whether the application of NPWT in laparostomy affects the haemodynamics. Midline incisions were made in six pigs followed by NPWT at -120 mmHg for 20 minut
Purpose: The aim of this study was to investigate how adult patients experience and cope with the anesthesia induction period, that is, before and during total intravenous induction. Design: Grounded theory, based on the Charmaz framework, was used to explore what it is that characterizes patients' thoughts and feelings in this situation and how they handle the time period up to loss of consciousn
OBJECTIVE.: To introduce a novel, simple, utility based outcome measure, the Number Needed per Quality adjusted life year (QALY) gained (NNQ), and to apply it in clinical practice in anti-TNF treated patients with rheumatoid arthritis (RA), psoriatic arthritis (PsA), and spondylarthritis (SpA). METHODS.: The NNQ is the number of patients one has to treat in order to gain 1 QALY. It is calculated a
Unilateral intrastriatal and intra-medial forebrain bundle injections of 6-OHDA impair the performance in a lateralised choice reaction time task. However, the extent and pattern of deficits after nigral 6-OHDA injections is less well studied, as well as the impact of training regime or the modification of various task parameters. The nigral 6-OHDA lesion resulted in impaired response accuracy and
BACKGROUND: Several reports have been published on the gender differences associated with allergies in mice. GOAL: In the present study we investigate the influence of gender on allergy response using a strain of mice, B10.RIII, which is commonly used in the collagen-induced arthritis murine model. METHODS: Both male and female B10.RIII young mice were immunized with OVA and challenged four times
Epidemiological studies have shown low-grade inflammation measured by high-sensitivity C-reactive protein (hs-CRP) to be associated with fracture risk in women. However, it is still unclear whether hs-CRP is also associated with fracture risk in men. We therefore measured serum levels of hs-CRP in 2910 men, mean age 75 years, included in the prospective population-based MrOS Sweden cohort. Study p
Pancreatic stellate cells (PSCs) play a key role in the dense desmoplastic stroma associated with pancreatic ductal adenocarcinoma. Studies on human PSCs have been minimal due to difficulty in maintaining primary PSC in culture. We have generated the first conditionally immortalized human non-tumor (NPSC) and tumor-derived (TPSC) pancreatic stellate cells via transformation with the temperature-se
Objective. Worldwide prevalence estimates of systemic lupus erythematosus (SLE) range from 3 to 207 per 100,000, depending on region and population, SLE definition, case sources, and other methodologic considerations. We aimed to determine the prevalence of SLE in Sweden on January 1, 2010, using population-based registers. Methods. Linking multiple national registers, we identified all possible i
Purpose: The purpose is to provide insight into how companies in practice work during packaging development to reduce negative environmental impacts along supply chains and to compare their practical approaches with the theoretical concepts presented in the literature. Design/methodology/approach: The research approach is explorative and based on nine cases (26 semi-structured interviews) in the f
This work attempts to investigate a long-standing tradition within the history of aesthetics according to which the function of pictorial representation consists, or ought to consist, of the rendering of general or idealized types rather than particulars. Proponents of this view may be found in various versions from antiquity to the present. The second chapter of this work gives a historical overv
Concrete structures in hydro power plants exposed to harsh environment, such as non-frozen freshwater and long cold winters with freezing temperatures, are always in the danger-zone for suffering from concrete damages. Some existing concrete structures already suffer from different damages caused by high water content. The conditions regarding concrete quality, air entrainment, temperature and tim
Clonal evolution in cancer is intimately linked to the concept of intratumor cellular diversity, as the latter is a prerequisite for Darwinian selection at the micro-level. It has been frequently suggested in the literature that clonal evolution can be promoted by an elevated rate of mutation in tumor cells, so-called genomic instability, the mechanisms of which are now becoming increasingly well
