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Objectives We sought to replicate the association between the kinesin-like protein 6 (KIF6) Trp719Arg polymorphism (rs20455), and clinical coronary artery disease (CAD). Background Recent prospective studies suggest that carriers of the 719Arg allele in KIF6 are at increased risk of clinical CAD compared with noncarriers. Methods The KIF6 Trp719Arg polymorphism (rs20455) was genotyped in 19 case-c
A general question for linkage disequilibrium-based association studies is how power to detect an association is compromised when tag SNPs are chosen from data in one population sample and then deployed in another sample. Specifically, it is important to know how well tags picked from the HapMap DNA samples capture the variation in other samples. To address this, we collected dense data uniformly
As the environmental impacts of buildings have become more and more eminent, so too has the demand and need for specialized green property services. Green property services refer to operative real estate management services, including both property and facility management, which promote environmental, or green, aspect of the services. This study sets out to identify the possible future development
Multiple system atrophy (MSA) is a horrible and unrelenting neurodegenerative disorder with an uncertain etiology and pathophysiology. MSA is a unique proteinopathy in which alpha-synuclein (α-syn) accumulates preferentially in oligodendroglia rather than neurons. Glial cytoplasmic inclusions (GCIs) of α-syn are thought to elicit changes in oligodendrocyte function, such as reduced neurotrophic su
Background: One of the global targets for non-communicable diseases is to halt, by 2025, the rise in the age standardised adult prevalence of diabetes at its 2010 levels. We aimed to estimate worldwide trends in diabetes, how likely it is for countries to achieve the global target, and how changes in prevalence, together with population growth and ageing, are aff ecting the number of adults with d
Objective: The aim of this study was to assess the risk of radiation-induced cancer development in patients that have undergone an infrarenal EVAR, stratifying the relative contributions of the procedure and the preoperative and postoperative CTAs. Methods and Materials: The organ-specific absorbed radiation doses from CTA and the EVAR procedure were estimated from the radiation exposures of 95 an
This article discusses the benefits and challenges of adding participant-producedphotographs to qualitative interviewing. The analysis is based on twoqualitative studies aimed at improving the understanding of how residentsexperience and use their a) luminaires and b) window openings. A conveniencesample (N = 12) was asked to take photographs of all luminaires intheir apartments. Facilitated by th
Background: Assessing and communicating software engineering research can be challenging. Design science is recognized as an appropriate research paradigm for applied research, but is rarely explicitly used as a way to present planned or achieved research contributions in software engineering. Applying the design science lens to software engineering research may improve the assessment and communic
This study conducted in-depth interviews with 20 managers and evaluation experts of social service organizations in China, with the aim of analyzing the organizational behaviors and motivations of social service organizations in response to the government-led evaluation. First, this paper classified the response strategies of social service institutions into ‘pursuing’, ‘coping’ and ‘avoiding’ bas
In order to fulfil the requirements of available energy resources, there is a great need to obtain a sustainable and environmentally friendly energy utilization using combustion processes. In order to do this, it is of utmost importance to utilize non-intrusive diagnostic techniques with high spatial and temporal resolution which can characterize the combustion process and also validate combustion
