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Parkinson’s disease is a neurodegenerative affliction to which researchers have long striven to find a cure. The human embryo is a source of vital cells used in regenerative medicine, as well as a powerful symbol of life. Using foetal cells from aborted embryos for transplantation to the brains of Parkinson patients is an avenue that has been explored by neuroscientists on and off for the last thi
A protocol was developed to study the drug uptake from in vivo electropermeabilization at different settings of parameters influencing the uptake efficiency. Radiolabelled diethylenetriaminepentaacetic acid (DTPA) was used to trace the distribution and internalization of a hydrophilic drug after in vivo electropermeabilization. Skeletal muscle tissue in rat was treated with permeabilizing electric
Several articles in the Recalling Fieldwork collection discuss the role of state surveillance and how it affected our ethnographic fieldwork. This was certainly the case in my own research in Romania in the decade from 1974-1985, where my secret police (Securitate) file ended up being over 600 pages long, and where I was blacklisted in 1985 due to hostile activities. Other ethnographers had simila
This chapter offers a reflection on the value of dialogue across media industries and academia in enhancing understanding of audience engagement and disengagement with media. The basis for this reflection is an industry-academic collaborative project between Lund University and Endemol Shine. The Media Experiences project conducted production and audience research on a range of drama and reality e
Language policy and planning (LPP) is one of the fastest growing sub-disciplines of applied linguistics. This book is the first volume that is exclusively devoted to research methods in language policy. As in other areas of applied linguistics, LPP scholars have drawn upon an array of research methods from a range of disciplines. This book is designed as a practical roadmap for those methods. Each
Some policymakers believe that academic R&D generates insufficient economic benefits. However, they often exclude the long-term and multi-dimensional impacts that are mediated through the activities of companies, students or policymakers. This case study, which is mainly interview-based, traces and characterises such impacts applying the technological innovation systems approach to the case of
Background: The success of selecting high risk or early-stage Alzheimer’s disease individuals for the delivery of clinical trials depends on the design and the appropriate recruitment of participants. Polygenic risk scores (PRS) show potential for identifying individuals at risk for Alzheimer’s disease (AD). Our study comprehensively examines AD PRS utility using various methods and models. Method
Refugee entrepreneurship has recently entailed increased scholarly mobilization and drastic growth in the volume of salient scientific research. However, this emerging research stream is marked by fragmentation and incoherence, primarily due to the multidisciplinary and context-specific nature of its extant findings. While this process is natural for emerging fields, the current state of research
To understand whether cerebrovascular events, a major complication of atherosclerosis, are associated with any specific DNA methylation changes in the carotid plaque.
Place branding is commonly understood as the general phenomenon of marketing, branding, promoting and regeneration of a particular city, region and/or location. Place branding has attracted an increasing number of researchers belonging to different disciplines producing a highly interdisciplinary literature. However, the complexity and problems connected with it has not been coped with sufficientl
A perspective overview is given describing the current development of multiplex mass spectrometry assay technology platforms utilized for high throughput clinical sample analysis. The development of targeted therapies with novel personalized medicine drugs will require new tools for monitoring efficacy and outcome that will rely on both the quantification of disease progression related biomarkers
Based on experiences from multiple international research projects, spanning several decades and utilizing various forms of collaborative ethnographic approaches, this article aims to reflect on challenges and potentials regarding language and communication when researching across jurisdictions. Thematically, the research projects that we draw on in this paper, are concerned with aging and healthc
Functional magnetic resonance imaging (fMRI) is increasingly used to non-invasively study the acute impact of psychedelics on the human brain. While fMRI is a promising tool for measuring brain function in response to psychedelics, it also has known methodological challenges. We conducted a systematic review of fMRI studies examining acute responses to experimentally administered psychedelics in o
AIMS: Reduced lung function and adverse health outcomes are often observed. This study characterizes genetic susceptibility for reduced lung function and risk of developing a range of adverse health outcomes.METHODS: We studied 27,438 middle-aged adults from the Malmö Diet and Cancer study (MDCS), followed up to 28.8 years. Trait-specific Polygenic scores (PGS) for forced expiratory volume in 1 s
