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Abnormalities in blood inflammatory markers have been associated with clinical manifestations and the pathogenesis of the fibromyalgia syndrome (FMS); a relationship between inherited alpha1-antitrypsin deficiency (AATD) and FMS has also been recently raised. In this study, plasma levels of inflammatory markers in FMS patients with and without AATD have been investigated. Blood samples from 138 ag
Using correlated ab initio methods, the polarizability of large [4n + 2]-annulenes is determined, showing that there exists an almost linear relation between the exaltation of magnetic susceptibility (a measure of aromaticity) and an equivalent enlargement of polarizability.
After a brief outlook on the field of concatenative synthesis of singing, with emphasis on the differences in comparison to synthesis of speech, the present paper gives an overview of a simple system for singing synthesis in Swedish based on concatenation of diphones. The system, called Burcas, accepts as input a text file for lyrics, from which it extracts a target phoneme sequence using basic le
Vital societal functions and critical infrastructure rely to an increasing extent on services from space, such as navigation and positioning systems, timekeeping, and communications. However, understanding of space service dependencies is low among practitioners and society at large, with research on societal space dependency being limited as well. In order to avoid cascading effects from disrupti
This thesis focuses on flexible work, known as telework, that is done through the use of information communication technology (ICT) devices in the entertainment, new media and arts sector. Fieldwork was conducted with independent professionals who work either as a producer / director, editor or motion graphic artist for the entertainment, new media and arts sector in the Los Angeles area. When wo
Finns det någon poäng med att övertyga gästerna om varumärkets storhet om inte de anställda är med på tåget? Det har påpekats att utan motiverade och nöjda anställda riskerar varumärkets och ledningens löften till gästerna att bli tomma, då det är personalen som ska leverera den utlovade servicen. Vi anser det intressant att undersöka hur företag inom hotellbranschen arbetar med att motivera sin p
3-Phosphoglycerate dehydrogenase (3-PGDH) deficiency is considered to be a rare cause of congenital microcephaly, infantile onset of intractable seizures and severe psychomotor retardation. Here, we report for the first time a very mild form of genetically confirmed 3-PGDH deficiency in two siblings with juvenile onset of absence seizures and mild developmental delay. Amino acid analysis showed se
Amino acids are not only indispensable for protein synthesis but also play important cellular functions. In this chapter, the central nervous system (CNS) functions of serine, glycine, and threonine are discussed. Both the specific functions of the aforementioned amino acids and the functions of their derivatives are reviewed in relation to brain development and neurotransmission. In particular, f
Congenital microcephaly, intractable seizures and severe psychomotor retardation characterize 3-phosphoglycerate dehydrogenase (3-PGDH) deficiency, a disorder of L-serine biosynthesis. The enzyme defect results in low concentrations of serine and to a variable degree of glycine in plasma and cerebrospinal fluid. Short-term beneficial effects have been reported of oral treatment with the deficient
BACKGROUND: TKA generally has excellent long-term survivorship. When a new knee system supersedes a previous model, increased survivorship, improved functional performance, or both may be expected, because key areas of design modification are often targeted to address wear, stability, and the patellofemoral articulation. However, not all design changes are beneficial, and to our knowledge, knee ar
The sedimentation of a suspension is a unit operation widely used in mineral processing, chemical engineering,wastewater treatment, and other industrial applications. Mathematical models that describe these processes and may be employed for simulation, design and control are usually given as nonlinear, time-dependent partial differential equations that in one space dimension include strongly degen
Aims: The Atrophodermas include a large group of disorders appearing as localized or widespread depressed skin areas and characterized by underlying dermal atrophy. The present study aims to report a peculiar form of previously unreported focal dermal atrophy. Methods: We studied over a period of 5 years a boy who manifested, since birth, multiple hypopigmented cutaneous atrophic lesions of the at
Purpose: This paper has chosen a participatory action design (PAD) to approach the construction of KPIs in a novel way. A PAD will assist the researcher to encourage involvement, engagement of multiple stakeholders in the KPIs construction process. Design/methodology/approach: A workshop series based on participatory action design was developed together with the researcher and stakeholders at the
This study aims at assess the importance of a conceptual representation of hydrological processes when modelling atmospheric circulation. It compares results from a regional atmospheric model that interprets land surface hydrological processes based on parameterizations with results from a two-way coupled atmosphere-hydrological model that has a process-based approach to the land surface hydrologi
