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Spherical Wave Array Based Positioning for Vehicular Scenarios

Smart vehicles are emerging as a possible solution for multiple concerns in road traffic, such as mobility and safety. This work presents radio localization methods based on simultaneous direction of arrival (DOA), time-delay, and range estimation using the SAGE algorithm. The proposed methods do not rely on external sources of information, such as global navigation satellite systems (GNSS). The p

Optimized vs. Standard Automated Peritoneal Dialysis Regimens (OptiStAR) : Study protocol for a randomized controlled crossover trial

Background: It has been estimated that automated peritoneal dialysis (APD) is currently the fastest growing renal replacement therapy in the world. However, in light of the growing number of diabetic patients on peritoneal dialysis (PD), the unwanted glucose absorption during APD remains problematic. Recent results, using an extended 3-pore model of APD, indicated that large reductions in glucose

Extinction and the temporal distribution of macroevolutionary bursts

Phenotypic evolution through deep time is slower than expected from microevolutionary rates. This is the paradox of stasis. Previous models suggest stasis occurs because populations track adaptive peaks that remain relatively stable on million-year intervals, raising the equally perplexing question of why these large changes are so rare. Here, we consider the possibility that peaks can move more r

Early Onset Ataxia with Comorbid Dystonia : Clinical, Anatomical and Biological Pathway Analysis Expose Shared Pathophysiology

In degenerative adult onset ataxia (AOA), dystonic comorbidity is attributed to one disease continuum. However, in early adult onset ataxia (EOA), the prevalence and pathogenesis of dystonic comorbidity (EOAD+), are still unclear. In 80 EOA-patients, we determined the EOAD+-prevalence in association with MRI-abnormalities. Subsequently, we explored underlying biological pathways by genetic network

Prophylactic treatment for severe haemophilia: comparison of an intermediate-dose to a high-dose regimen

A multicentre study was performed in Sweden and the Netherlands, comparing effects of two prophylactic regimens in 128 patients with severe haemophilia, born 1970-90. 42 Swedish patients (high-dose prophylaxis), were compared with 86 Dutch patients (intermediate-dose prophylaxis). Patients were evaluated at the date of their last radiological score according to Pettersson. Annual clotting factor c

The integral dictionary: A lexical network based on componential semantics

The Integral Dictionary is a comprehensive lexical network for French, English, German, Italian, and Spanish. It is based on componential semantics and lexical functions. The network structure superimposes two graphs. A first graph consists of a hierarchy of concepts divided into classes and themes where the words form the terminal nodes of the graph. A second graph links the words together using

Secretion of ghrelin from rat stomach ghrelin cells in response to local microinfusion of candidate messenger compounds: A microdialysis study

Ghrelin is produced by A-like cells (ghrelin cells) in the mucosa of the acid-producing part of the stomach. The mobilization of ghrelin is stimulated by nutritional deficiency and suppressed by nutritional abundance. In an attempt to identify neurotransmitters and regulatory peptides that may contribute to the physiological, nutrient-related regulation of ghrelin secretion, we challenged the ghre

Validation of the Dutch version of the Hip Disability and Osteoarthritis Outcome Score

Introduction: The Hip disability and Osteoarthritis Outcome Score (HOOS) was constructed in Sweden; this questionnaire has proved to be valid for persons with hip disability with or without hip osteoarthritis (OA) and with high demands of physical function. Objective: The objective of this study was to evaluate the internal consistency, reliability, construct validity, and floor and ceiling effect

Resonant auger decay of above-threshold core-excited H2O

The decay properties of an above-threshold resonance in core-ionized water, which is difficult to. identify with usual spectroscopic methods, have been analyzed by resonant Auger spectroscopy. The resonance is. shown to correspond to a doubly excited neutral state embedded in the O 1s ionization continuum. The main, result of the experiments is the assessment on the dissociative nature of the inte

Validating the existence of the supercraton Vaalbara in the Mesoarchaean to Palaeoproterozoic

Det är allmänt känt att kontinenter under Jordens historia har separerat och kolliderat i ett cykliskt förlopp vilket har lett till existensen av större landmassor, superkontinenter eller superkratoner under vissa tidsperioder. En av de tidigaste föreslagna superkratonerna är Vaalbara, som sedan 1960-talet har ansetts bestå av Kaapvaalkratonen i södra Afrika och Pilbarakratonen i västra AustralienIn this thesis, the longevity and continuity of the Vaalbara supercraton is addressed in six papers aimed at placing new temporal and spatial constraints onthe supercraton in the Mesoarchean to Paleoproterozoic. It has been speculated since the 1960’s that the Kaapvaal Craton in southern Africa, together withthe Pilbara Craton in Western Australia existed as a single landmass during the Precambria

Vertical transmission of a nematode from female lizards to the brains of their offspring

Parasites have evolved a diversity of lifestyles that exploit the biology of their hosts. Some nematodes that parasitize mammals pass via the placenta or milk from one host to another. Similar cases of vertical transmission have never been reported in avian and nonavian reptiles, suggesting that egg laying may constrain the means of parasite transmission. However, here we report the first incidenc

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In this clinical case, the importance of early detection of Hurler syndrome for outcomes of stem cell transplantation in this patient population is illustrated. Nowadays, children with Hurler syndrome can be treated with stem cell transplantation, but the results largely depend on the moment of treatment. If the procedure is initiated in an early stage of disease, better results can be obtained. T

Tools for protective lung ventilation. The elastic pressure-volume curve and aspiration of dead space

Popular Abstract in Swedish Mekanisk ventilation kan medföra "ventilationsinducerad lungskada" (VILI), som kan öka sjuklighet och dödlighet i samband med akut lungskada (ALI). Flera ventilationssätt har föreslagits för att undvika VILI, men inte slutgiltigt utvärderats. En princip är att öka alveolär ventilation och CO2-elimination genom att minska ventilationen av de skadliga rummet, dead space. Ventilator-induced lung injury (VILI) may contribute to morbidity and mortality of acute lung injury (ALI). Lung protective ventilation (LPV), that reduces VILI, may involve low tidal volume (Vt). Particularly low Vt is possible if dead space ventilation is reduced e.g. by aspiration of dead space gas (ASPIDS). ASPIDS implies that gas rich in CO2 during expiration is aspirated through a separate c

Present limitations of models for predicting chloride ingress into reinforced concrete structures

Models to predict chloride ingress are numerous but all of them have serious limitations that restrict the present use for long term predictions. An overview is given of the fundamental differences between various models, from those based on Fick's 2nd with constant or time-dependent diffusion coefficients and surface chloride contents, to those based on chloride transport equations with or withou

Hypertension, haematuria and renal functioning in haemophilia - a cross-sectional study in Europe

Background and objectives: This cross-sectional, epidemiological study sought to assess the prevalence and extent of potential risk factors for hypertension, particularly renal function related to haematuria and their associations in people with haemophilia. Methodology: Demographic and medical data were collected at a single time-point in patients with haemophilia over 40 years of age from 16 Eur

New U–Pb geochronologic and palaeomagnetic constraints on the late Palaeoproterozoic Hartley magmatic event : evidence for a potential large igneous province in the Kaapvaal Craton during Kalahari assembly, South Africa

The volcanic Hartley Formation (part of the Olifantshoek Supergroup, which is dominated by red bed successions) in South Africa recorded depositional and tectonic conditions along the western Kaapvaal Craton during the late Palaeoproterozoic. It formed in association with red bed deposition elsewhere in the cratonic hinterland and along the craton’s northern margin. However, the exact correlation

Doppler interference in dissociative resonant photoemission

Resonant photoemission involving dissociative core excited states has been the subject of a great number of experimental and theoretical investigations in recent time. The resonant decay of such dissociating systems has been shown to lead to semiatomic Auger electron emission spectra, with particular angular behavior. In the present paper a detailed theoretical analysis of dissociative resonant ph