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Abnormalities in blood inflammatory markers have been associated with clinical manifestations and the pathogenesis of the fibromyalgia syndrome (FMS); a relationship between inherited alpha1-antitrypsin deficiency (AATD) and FMS has also been recently raised. In this study, plasma levels of inflammatory markers in FMS patients with and without AATD have been investigated. Blood samples from 138 ag
After a brief outlook on the field of concatenative synthesis of singing, with emphasis on the differences in comparison to synthesis of speech, the present paper gives an overview of a simple system for singing synthesis in Swedish based on concatenation of diphones. The system, called Burcas, accepts as input a text file for lyrics, from which it extracts a target phoneme sequence using basic le
The topic of Basic Colour Terms (BCT) and their proposed universality has long been a source of debate within linguistics. Whether colour terms (as symbols) fill lexical gaps of presumed universal colour categories (as senses) or not is relevant for the debate regarding linguistic relativity: the hypothesis about the influence of language on the way we think. Until now, there has been a focus on
This thesis focuses on flexible work, known as telework, that is done through the use of information communication technology (ICT) devices in the entertainment, new media and arts sector. Fieldwork was conducted with independent professionals who work either as a producer / director, editor or motion graphic artist for the entertainment, new media and arts sector in the Los Angeles area. When wo
Finns det någon poäng med att övertyga gästerna om varumärkets storhet om inte de anställda är med på tåget? Det har påpekats att utan motiverade och nöjda anställda riskerar varumärkets och ledningens löften till gästerna att bli tomma, då det är personalen som ska leverera den utlovade servicen. Vi anser det intressant att undersöka hur företag inom hotellbranschen arbetar med att motivera sin p
This study aims at assess the importance of a conceptual representation of hydrological processes when modelling atmospheric circulation. It compares results from a regional atmospheric model that interprets land surface hydrological processes based on parameterizations with results from a two-way coupled atmosphere-hydrological model that has a process-based approach to the land surface hydrologi
3-Phosphoglycerate dehydrogenase (3-PGDH) deficiency is considered to be a rare cause of congenital microcephaly, infantile onset of intractable seizures and severe psychomotor retardation. Here, we report for the first time a very mild form of genetically confirmed 3-PGDH deficiency in two siblings with juvenile onset of absence seizures and mild developmental delay. Amino acid analysis showed se
Amino acids are not only indispensable for protein synthesis but also play important cellular functions. In this chapter, the central nervous system (CNS) functions of serine, glycine, and threonine are discussed. Both the specific functions of the aforementioned amino acids and the functions of their derivatives are reviewed in relation to brain development and neurotransmission. In particular, f
Congenital microcephaly, intractable seizures and severe psychomotor retardation characterize 3-phosphoglycerate dehydrogenase (3-PGDH) deficiency, a disorder of L-serine biosynthesis. The enzyme defect results in low concentrations of serine and to a variable degree of glycine in plasma and cerebrospinal fluid. Short-term beneficial effects have been reported of oral treatment with the deficient
Plastics are versatile, cheap and durable materials that are omnipresent in modern society. Since most of them are derived from crude oil and are not biodegradable, their production leads to the depletion of fossil fuels and the accumulation of enormous amounts of plastic waste that pollutes ecosystems worldwide. For this reason, the European Union and other organisations are investing in research
The present thesis investigated how listeners use prosody to rapidly predict upcoming lexical and syntactic structures. In the first three studies, it was shown that listeners take advantage of Swedish word-level tones to pre- activate upcoming word endings. Every Swedish word has a tone on the word stem – known as a ‘word accent’ – which is either low or high, and the tone is assigned to the stem
This paper presents a method for the design of nonuniform DFT filter banks for subband beamforming. Filter banks designed with the method are evaluated in subband beamforming in a real-world microphone array application. Different source positions in array applications give rise to different signal delays, which means that adaptive beamformers in the subbands alter the phase information of the sub
The laminar burning velocity is a fundamental property of combustiblemixtures important for kinetic model validation as well as for practicalapplications. Many efforts are directed towards its accurate determination.The heat flux method is one of the commonly recognized methodsfor measuring laminar burning velocity, however, the information on theaccuracy of the method is scattered in the literatu
Local delivery of amyloid beta oligomers from the tip of a nanopipette, controlled over the cell surface, has been used to deliver physiological picomolar oligomer concentrations to primary astrocytes or neurons. Calcium influx was observed when as few as 2000 oligomers were delivered to the cell surface. When the dosing of oligomers was stopped the intracellular calcium returned to basal levels o
