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Quo Vadis, energy performance gap?

The topic of the energy performance gap (the difference between predicted and measured energy use) attracts significant attention in the building simulation community. This viewpoint article, which doubles as an editorial on this subject matter, provides an overview of recent trends in the area, whilst also providing a critique on three main issues: (1) the need to specify in some detail what type

Peacebuilding round table

With considerable flux in the peace and conflict landscape, scholars, policymakers, practitioners and publics alike are scrambling to understand emerging realities. Moreover, a sometimes slow academic publishing cycle means that much material appearing in academic journals seems already outdated–reporting on a peace and conflict landscape as though we are still in an era of comprehensive peace pro

Nucleobase catalysts for the enzymatic activation of 8-oxoguanine DNA glycosylase 1

Bifunctional DNA glycosylases employ an active site lysine or the N-terminus to form a Schiff base with an abasic (AP) site base excision repair intermediate. For 8-oxoguanine DNA glycosylase 1 (OGG1), cleaving this reversible structure is the rate-determining step in the initiation of 8-oxoguanine (8-oxoG) repair in DNA. Evolution has led OGG1 to use a product-assisted catalysis approach, where t

SWEAH Verksamhetsberättelse 2022, Fastställd

Nationella forskarskolan om åldrande och hälsa Fastställd av SWEAH:s styrelse 230330 Verksamhetsberättelse 2022 Nationella forskarskolan om åldrande och hälsa www.sweah.lu.se http://www.sweah.lu.se/ Nationella forskarskolan om åldrande och hälsa Verksamhetsberättelse 2022 2 Innehållsförteckning sida Sammanfattning 3 Första året med ny finansieringsform 4 Styrelse 5 Forskarskolans ledning och admin

https://www.sweah.lu.se/sites/sweah.lu.se/files/2023-05/SWEAH%20verksamhetsber%C3%A4ttelse%202022,%20fastst%C3%A4lld.pdf - 2026-05-29

166 MP131 Jonsdottir JCEM 2024

Early Appearance of Thyroid Autoimmunity in Children Followed From Birth for Type 1 Diabetes Risk Early Appearance of Thyroid Autoimmunity in Children Followed From Birth for Type 1 Diabetes Risk Berglind Jonsdottir,1,2 Joanna L. Clasen,3 Kendra Vehik,3 Åke Lernmark,2 Markus Lundgren,2 Ezio Bonifacio,4 Desmond Schatz,5 Anette-Gabriele Ziegler,6,7,8 William Hagopian,9 Marian Rewers,10 Richard McInd

https://www.teddy.lu.se/sites/teddy.lu.se/files/2024-12/166_MP131_Jonsdottir_JCEM_2024.pdf - 2026-05-29

Short-term clinical follow-up of the treatment of aortic coarctation with a new generation of device

Coarctation of the aorta is a congenital heart anomalyinvolving constriction of an aortic segment, associated with wall thickening of media and the formationof overlapping infolding of neointimal tissue. For thefirst time it was described by Morgagni in 1760. Thispathology represents 5% -7% of all congenital heartdiseases, with an incidence of approximately 3 casesto 10 000 neonates1. The typical

Amino Acid Synthesis Deficiencies

In recent years the list of disorders affecting amino acid synthesis has grown rapidly. Not only the number of defects has increased, but also the associated clinical phenotypes have expanded spectacular, the latter mainly due to the advances of next-generation sequencing diagnostics. An important reason for the contribution of NGS in the diagnosis of amino acid synthesis disorders is the fact tha

An Investigation of the Relationship between Personality, Cognitive Ability, and Work Engagement in Intellectually Gifted Individuals

Do personality traits in highly intelligent individuals relate to their work engagement? Seemingly little is known about the relationship between personality and work engagement for gifted individuals. In what may be the first study to do so, a Swedish Mensa sample (n = 353) was explored with a two-part aim: to assess psychometric personality properties and to investigate the relationship between

Customer engagement design in industrial innovation

While the design of goods and services is undeniably important in cultivating customer engagement (CE) with industrial innovations, the theoretical interface of industrial design, innovation, and CE remains nebulous, exposing an important literature-based gap. Relatedly, while the literature has focused on the firm as the focal designing stakeholder, further knowledge building is needed regarding

Ethanol in Aqueous Solution Studied by Microjet Photoelectron Spectroscopy and Theory

ConspectusBy combining results and analysis from cylindrical microjet photoelectron spectroscopy (cMJ-PES) and theoretical simulations, we unravel the microscopic properties of ethanol-water solutions with respect to structure and intermolecular bonding patterns following the full concentration scale from 0 to 100% ethanol content. In particular, we highlight the salient differences between bulk a

Exploiting the Transformative Features of Metal Halides for the Synthesis of CsPbBr3@SiO2 Core-Shell Nanocrystals

The encapsulation of colloidal lead halide perovskite nanocrystals within silica (SiO2) is one of the strategies to protect them from polar solvents and other external factors. Here, we demonstrate the overcoating of CsPbBr3 perovskite nanocrystals with silica by exploiting the anhydride-induced transformation of Cs4PbBr6 nanocrystals. CsPbBr3@SiO2 core–shell nanocrystals are obtained after (i) a

Evaluation of threshold-based models to account for surface moisture in meso-scale aeolian sediment transport simulations

Aeolian transport rates decreases during wet conditions as the threshold shear velocity for initiation of transport increases over moist sand. This study investigates the influence of surface moisture on meso-scale aeolian transport simulations. Yearly transport rates towards the dunes are simulated with ten different threshold-based models to account for moisture effects. The ten models show larg

Evidence of Site-Specific and Male-Biased Germline Mutation Rate in a Wild Songbird

Germline mutations are the ultimate source of genetic variation and the raw material for organismal evolution. Despite their significance, the frequency and genomic locations of mutations, as well as potential sex bias, are yet to be widely investigated in most species. To address these gaps, we conducted whole-genome sequencing of 12 great reed warblers (Acrocephalus arundinaceus) in a pedigree s

Reporting Bone Cytopathology-A Proposal Based on a Single Tertiary Centre Experience

OBJECTIVE: Fine-needle aspiration cytology (FNAC) from bone lesions has been proven to be a useful diagnostic tool but lacks standardisation. The aim of the study was to evaluate the diagnostic utility of FNAC as a basis to propose and test a reporting system for bone reporting cytopathology.METHODS: This retrospective study is based on patients with bone lesions, that were approached by cytology

The finitely generated Hausdorff spectra of a family of pro-p groups

Recently the first example of a family of pro-p groups, for p a prime, with full normal Hausdorff spectrum was constructed. In this paper we further investigate this family by computing their finitely generated Hausdorff spectrum with respect to each of the five standard filtration series: the p-power series, the iterated p-power series, the lower p-series, the Frattini series and the dimension su

Superficial Tale of Two Functional Groups : On the Surface Propensity of Aqueous Carboxylic Acids, Alkyl Amines, and Amino Acids

ConspectusThe gas-liquid interface of water is environmentally relevant due to the abundance of aqueous aerosol particles in the atmosphere. Aqueous aerosols often contain a significant fraction of organics. As aerosol particles are small, surface effects are substantial but not yet well understood. One starting point for studying the surface of aerosols is to investigate the surface of aqueous so