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Background and Objectives: Photodynamic therapy using 20% 5 aminolevulinic acid (5-ALA) has recently been introduced as a new tool in optical skin rejuvenation. The primary objective of this study was to optimize incubation time, the topical delivery mechanism (vehicle) and the concentration of 5-ALA by detecting the dynamic changes of normal skin after 5-ALA application. The secondary objective w
Background: De novo lymphatic vessel formation has recently been observed in lungs of patients with moderate chronic obstructive pulmonary disease (COPD). However, the distribution of lymphatic vessel changes among the anatomical compartments of diseased lungs is unknown. Furthermore, information regarding the nature of lymphatic vessel alterations across different stages of COPD is missing. This
Popular Abstract in Swedish Knäartros är en mycket vanlig sjukdom som leder till successiv nedbrytning och förlust av brosket i leden, en process som oftast tar 10-20 år. Detta orsakar svår smärta och stelhet och i dag saknas botande behandling mot artros. Det är dock rimligt att anta att en behandling har bättre förutsättningar att lyckas ju tidigare den sätts in. Man vet att det tidigt under sjuDelayed gadolinium-enhanced MRI of cartilage (dGEMRIC) is a new technique to study cartilage glycosaminoglycan (GAG) content. The negatively charged contrast agent Gd-DTPA2-, injected intravenously, distributes in the cartilage inversely to the likewise negatively charged GAG. The GAG concentration is reflected by the MRI parameter T1 and the Gd-DTPA2- concentration by the MRI parameter R1 (R1=1/T
This study aimed to test and validate a dual-time-window (DTW) protocol for 6-(fluoro-18F)-3-(1H-pyrrolo[2,3-c]pyridin-1-yl)isoquinolin-5-amine ([18F]MK6240) dynamic PET imaging in experimental datasets acquired in human subjects. Methods: DTW protocols were tested and validated in datasets previously collected in 25 participants: 13 were cognitively normal, 10 had mild cognitive impairment, and 2
Anthropogenic changes to the environment expose wildlife to many pollutants. Among these, tropospheric ozone is of global concern and a highly potent pro-oxidant. In addition, human activities include several other implications for wildlife, e.g., changed food availability and changed distribution of pathogens in cities. These co-occurring habitat changes may interact, thereby modulating the physi
Inom nuklearmedicinen utnyttjas radioaktiva läkemedel och strålningen som sänds ut från dessa för att diagnosticera och behandla ett flertal olika sjukdomar. Det radioaktiva läkemedlet ges ofta till patienten som en intravenös injektion, och läkemedlets egenskaper i kombination med patientens fysiologi och eventuella sjukdom avgör hur läkemedlet sedan fördelas, omsätts och utsöndras från kroppen. Many nuclear medicine investigations rely on gamma-camera imaging to study and quantify the distribution of radiopharmaceuticals or radionuclides in the patient as a function of time. This is typically used for diagnostic studies of physiological functions or for calculation of absorbed doses following radionuclide therapy. In this work, computational patient models (phantoms) have been developed
Background: Experimental analyses of the 3D strain field evolution during loading allows for better understanding of deformation and failure mechanisms at the meso- and microscale in different materials. In order to understand the auxetic behaviour and delamination process in paperboard materials during tensile deformation, it is essential to study the out-of-plane component of the strain tensor t
BACKGROUND: Knowledge is limited regarding the association between stem cells in histologically benign breast tissue and risk factors for breast cancer, and hence we addressed this issue in the present study. Recently, we assessed the histology of benign breast tissue from cancer and non-cancer patients for cells positive for the putative stem cell marker aldehyde dehydrogenase 1 A1 (ALDH), and th
Breast cancer is the most common type of cancer worldwide with an estimate of 2.3 million new cases in 2020, and the number one cause of cancer-related deaths in women. While survival rates are high in many high-income countries, with a five year relative survival rate of 85% and more, the respective survival rates are poor in many middle- and low-income countries, with rates as low as 12% in Kyad
Achilles tendon rupture is becoming more prevalent with an increasing population of middle aged people participating in recreational sports. A torn Achilles tendon will likely not regain its original function, and it is unknown what treatment options are optimal. The Achilles tendon structure and how the tendon heals after a rupture varies between humans. A potentially useful tool in understanding
In Paper I, 4703 subjects from the Malmö Cost Cancer cohort, with a mean follow-up of 16.5 years, were evaluated for future risk of ischemic stroke in relation to levels of s-LOX1. An increased risk was found for higher level of sLOX-1 OR 1.75 (1.28-2.39), p<0.001, increasing in presence of carotid plaque OR 2.42 (1.71-3.44), p<0.001. Endothelial cells were exposed to oxLDL, resulting in release o
The focus in this thesis has been active power from small scale solar production and what possible impacts an increased proportion of small scale production can have, in a larger context, during short circuit (SC) faults in the grid. The main research question prompting this work was whether active power from small scale solar pro- duction can help support voltages during SC faults, and meet LVRT-
Wood-based light-weight I-beams are today widely used in the construction industry. An important feature of these beams is that the user can make holes in the web where needed. Today there is no general method used to calculate the reduced strength of these beams with a hole in the web. The calculation methods vary between the manufacturers and are commonly based on empirical results. The aim of t
Nitric oxide (NO)/cyclic GMP (cGMP)-mediated mechanisms have a pivotal function in reducing the tone of the penile smooth musculature during normal erectile responses. The cyclic AMP ( cAMP) signaling pathway is also involved in the adjustment of smooth muscle contractility, and suggestions for interactions between cGMP- and cAMP-mediated mechanisms have been presented. Using activators of the cGM
NGEK01 course evaluation 2019 Physical Geography LU Course Summary for NGEK01, Physical Geography and Ecosystem Analysis:Bachelor's Degree Project, 15 credits vt 2019 Course coordinator: Jonas Ardö Teachers in the course: Jonas Ardö, Ladaea Rylander (Studieverkstaden) Charlotte Webb (Studieverkstaden), Britta Smångs (Geobiblioteket) Supervisors: Andreas Persson, Dan Metcalfe, Fredrik Lagergren, Ha
https://www.nateko.lu.se/sites/nateko.lu.se/files/2021-01/ngek01_course_evaluation_2019.pdf - 2026-09-11
Department of Mechanical Engineering Solid Mechanics ISRN LUTFD2/TFHF–06/5118-SE(1-105) ROBUSTNESS ANALYSIS OF FE-MODELS Master’s Dissertation by LINDA NILSSON Supervisors Jan Reger, P+Z Engineering GmbH, Germany Mathias Wallin, Div. of Solid Mechanics, Lund University, Sweden Ulf Nyman, Div. of Solid Mechanics, Lund University, Sweden Copyright c© 2006 by Div. of Solid Mechanics, P+Z Engineering
https://www.solid.lth.se/fileadmin/hallfasthetslara/utbildning/examensarbete/TFHF5118.pdf - 2026-09-10
2006 Cronqvist M, Wirestam R, Ramgren B, Brandt L, Romner B, Nilsson O, Saveland H, Holtås S, Larsson EM:Endovascular Treatment of Intracerebral Arteriovenous Malformations: Procedural Safety, Complications, and Results Evaluated by MR Imaging, Including Diffusion and Perfusion Imaging. Am. J. Neuroradiol. 2006 Jan;27(1):162-76. Elfgren C, van Westen D, Passant U, Larsson EM, Mannfolk P, Fransson
https://www.msf.lu.se/research/mr-physics-group/publications/papers/1994-2006 - 2026-09-09
Sverige saknar i dag ett särskilt konstitutionellt regelverk för hantering av allvarliga fredstida krissituationer motsvarande det som gäller vid krig och krigsfara. Erfarenheterna från covid-19-pandemin har emellertid aktualiserat frågan om den svenska konstitutionella beredskapen är tillräcklig under fredstida kriser. Mot denna bakgrund har riksdagen som vilande antagit ett grundlagsförslag om eSweden currently lacks a specific constitutional framework for managing severe peacetime crises comparable to the emergency provisions applicable in times of war or danger of war. The experiences of the COVID-19 pandemic have nevertheless raised questions regarding whether the existing constitutional framework provides sufficient capacity to respond effectively to extraordinary peacetime emergenci
Postdoctoral fellow Contact details Email: omar [dot] karlsson [at] ekh [dot] lu [dot] seOrganisation Department of Economic History Service point: 10 WebpageOmar Karlssons profile in Lund University research portalOther affiliations Postdoctoral fellow Economic demography Postdoctoral fellow Centre for Economic Demography Publications Displaying of publications. Sorted by year, then title. Filter
https://www.lusem.lu.se/omar-karlsson - 2026-09-10
Proteinförändringar avslöjar sjukdomar – Vetenskap och Hälsa Hoppa till innehåll Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Proteinförändringar avslöjar sjukdomar 2025-05-16 Olika organ har specifika protein-fingeravtryck i blodet även under normala omständigheter, men vid en organskada eller sjukdom förän
https://www.vetenskaphalsa.se/proteinforandringar-avslojar-sjukdomar/ - 2026-09-10
