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To determine the functions of fibromodulin (Fmod), a small leucine-rich keratan sulfate proteoglycan in tooth formation, we investigated the distribution of Fmod in dental tissues by immunohistochemistry and characterized the dental phenotype of 1-day-old Fmod-deficient mice using light and transmission electron microscopy. Immunohistochemistry was also used to compare the relative protein express
Purpose: The aim of the present study is to compare two different methods for evaluation of the quality of clinical X-ray images. Methods: Based on fifteen lumbar spine radiographs, two new sets of images were created. A hybrid image set was created by adding two distributions of artificial lesions to each original image. The image quality parameters spatial resolution and noise were manipulated a
Type II diabetes is caused by a failure of the pancreatic beta-cells to compensate for insulin resistance leading to hyperglycaemia. There is evidence for an essential role of an increased beta-cell apoptosis in type II diabetes. High glucose concentrations induce IL-1 beta production in human beta-cells, Fas expression and concomitant apoptosis owing to a constitutive expression of FasL. FASL and
Objective This study aimed to explore the potential of in vivo q-space imaging in the differentiation between different cerebral water components. Materials and Methods Diffusion-weighted imaging was performed in six directions with 32 equally spaced q values and a maximum b value of 6600 s/mm2. The shape of the signal-attenuation curve and the displacement propagator were examined and compared
Although the benefits of topical sensitizer administration have been confirmed for photodynamic therapy (PDT) ALA-induced, protoporphyrin IX is the only sensitizer clinically used with this administration route. Unfortunately, ALA-PDT results in poor treatment response for thicker lesions. Here, selectivity and depth distribution of the highly potent sensitizer meso-tetra(hydroxyphenyl)chlorin (mT
An empirical equation for the magnetization transfer (MT) FLASH signal is derived by analogy to dual-excitation FLASH, introducing a novel semiquantitative parameter for MT, the percentage saturation imposed by one MT pulse during TR. This parameter is obtained by a linear transformation of the inverse signal, using two reference experiments of proton density and T1 weighting. The influence of seq
The human endometrium is a dynamic tissue, which undergoes extensive tissue remodelling during the menstrual cycle. Due to their involvement in such processes, several well-characterized matrix metalloproteinases (MMP) have previously been studied in the endometrium. MMP-26 is a newly described matrilysin. We studied MMP-26 mRNA in 39 normal endometrial samples obtained across the menstrual cycle.
Purpose of review Few human studies have been performed with specific genetic endpoints coupled with erectile function or dysfunction. Most knowledge of gene expression and the function thereof on penile erection has been aqcuired in experimental models. The purpose of the present review is to give an overview of the available information obtained in studies of genes or genetic products versus ere
In patients with severe head injuries raised intracranial pressure (ICP) constitutes the most important cause of mortality. Several new therapies for increased ICP have recently been suggested and it is of importance to study the physiological effects of these treatments in animal experiments during steady state conditions. A porcine model for evaluation of cerebral haemodynamics and metabolism du
Assessment of image analysis methods and computer software used in (99m) Tc-MAG3 dynamic renography is important to ensure reliable study results and ultimately the best possible care for patients. In this work, we present a national multicentre study of the quantification accuracy in (99m) Tc-MAG3 renography, utilizing virtual dynamic scintigraphic data obtained by Monte Carlo-simulated scintilla
Då klimatförändringar studeras är det viktigt att ha markanvändningarna och deras förändringar i åtanke. Markanvändningarna är direkt och indirekt relaterat till klimatförändringar såsom exempelvis stigande temperaturer, vilket påskyndar starten av växtsäsongen. Fjärranalysdata ger en bättre bild av storskaliga förändringar i vegetationen än vad som är möjligt att observera från jordytan. VegetatiWith respect to climate change it is necessary to study land use and land cover (LULC) and their changes. LULC are related directly and indirectly to climatic changes such as rising temperatures that trigger earlier onset of vegetation growing seasons (IPCC 2007). Land surface phenology refers to the seasonal patterns of variation in vegetated land surfaces over large areas using satellite data (R
Windahl SH, Andersson N, Chagin AS, Martensson UEA, Carlsten H, Olde B, Swanson C, Moverare-Skrtic S, Savendahl L, Lager-quist MK, Leeb-Lundberg LMF, Ohlsson C. The role of the G protein-coupled receptor GPR30 in the effects of estrogen in ovariectomized mice. Am J Physiol Endocrinol Metab 296: E490-E496, 2009. First published December 23, 2008; doi:10.1152/ajpendo.90691.2008.-In vitro studies sug
During severe storms high waves and water levels may greatly impact the sub-aerial portion of the beach inducing significant morphological change at elevations that the waves can not reach under normal conditions. Morphological formations such as dunes and barrier islands may suffer from direct wave impact and erode. Overwash occurs if the wave run-up and/or the mean water level are sufficiently h
The purpose of this study is to determine whether it is easier to predict the default probability in EU than in the USA or vice versa by analyzing the time period 2006-2009 which is characterized by the financial crisis. We will also establish whether there are any differences in the prediction of default probabilities between non-financial and financial firms. To be able to perform the study, we
Dynamic glucose enhanced (DGE) MRI is used to study the signal intensity time course (tissue response curve) after D-glucose injection. D-glucose has potential as a biodegradable alternative or complement to gadolinium-based contrast agents, with DGE being comparable to dynamic contrast enhanced (DCE) MRI. However, the tissue uptake kinetics as well as the detection methods of DGE differ from DCE,
Lathund inför disputation Soc io log iska ins t i tu t ionen Från slutseminarium till disputation – för doktoranden För blanketter och mer detaljerad information om tryckning, spikning etc., se Samhällsvetenskapliga fakultetens hemsida. https://www.sam.lu.se/internt/forska- och-utbilda/forskarutbildning/disputation Slutseminarium Samtliga avhandlingsmanus vid sociologiska institutionen ska behandl
https://www.soc.lu.se/sites/soc.lu.se/files/2025-02/Lathund_infor_disputation_Doktorander_20241211.pdf - 2026-09-09
African food security has become an increasing concern during the last decade. Reports are regularly appearing about famine and hunger in countries south of the Sahara. Pessimism is widespread about the possibilities for the continent to feed its growing population. Until recently, optimism about Asian development on the other hand seemed boundless, and Asia is considered the emerging centre of th
https://www.keg.lu.se/en/research/research-projects/current-research-projects/afrint/afrint-i - 2026-09-09
Penalty shootouts have become paradigmatic for research on anticipatory skills and decision making. The present study examines the dynamics of goal side selection when viewing realistic images depicting a penalty kick scenario. A sample of participants (n=40) was drawn from a population of students from Lund University. Participants viewed realistic images of a goalkeeper, soccer goal, and ball pl
