Filtyp
This study aimed to disentangle the influence of information status and referential form on the distribution of gestures in sustained discourse. Previous research shows that new/less accessible rather than old/more accessible information, expressed by rich rather than lean referential forms, is more likely to be accompanied by gestures. However, earlier studies have drawn on correlational results.
Molecular radiotherapy combines the advantages of systemic administration of highly specific antibodies or peptides and the localized potency of ionizing radiation. A potential target for molecular radiotherapy is the cell surface antigen CD44v6, which is overexpressed in numerous cancers, with limited expression in normal tissues. The aim of the present study was to generate and characterize a pa
A common issue affecting DNA methylation analysis in tumor tissue is the presence of a substantial amount of non-tumor methylation signal derived from the surrounding microenvironment. Although approaches for quantifying and correcting for the infiltration component have been proposed previously, we believe these have not fully addressed the issue in a comprehensive and universally applicable way.
Electrospinning is a versatile technique for manufacturing micro-nano diameter fibers and has been used extensively for tissue engineering in vivo and advanced cell culture in vitro. Standard means of seeding cells onto such substrates typically offer no control over cell distribution, yielding dispersed, heterogeneous and low concentrations of cells. In this article, we investigate the viability
Background: Irradiation with ultra-high dose rate (FLASH) has been shown to spare normal tissue without hampering tumor control in several in vivo studies. Few cell lines have been investigated in vitro, and previous results are inconsistent. Assuming that oxygen depletion accounts for the FLASH sparing effect, no sparing should appear for cells irradiated with low doses in normoxia. Methods: Seve
Anemia, which may develop due to direct effect of the virus or indirect effect of zidovudine a widely used antiviral agent for the treatment, is not an uncommon complication in human immundeficiency virus (HIV) infections. In this report, a 26 years old male HIV positive patient who developed rapid anemia in the HAART (Highly active anti-retroviral therapy) protocol including zidovudine, was prese
Solid tumors exhibit chromosomal rearrangements resulting in gain or loss of multiple chromosomal loci (copy number variation, or CNV), and translocations that occasionally result in the creation of novel chimeric genes. In the case of breast cancer, although most individual tumors each have unique CNV landscape, the breakpoints, as measured over large datasets, appear to be non-randomly distribut
OBJECTIVE:: To compare the intracranial pressure after resuscitation to normovolemia by using 20% albumin or normal saline in a cat model of meningitis. DESIGN:: Prospective, randomized animal study. SETTING:: University hospital laboratory. SUBJECTS:: Twenty adult, male cats. INTERVENTIONS:: Meningitis was induced by intrathecal injection of Escherichia coli-derived lipopolysaccharide (0.8 × 10 u
A new type of polymer gel dosimeter, which responds well to absorbed dose even when manufactured in the presence of normal levels of oxygen, was recently described by Fong et al. [Phys. Med. Biol. 46, 3105-3113 (2001)] and referred to by the acronym MAGIC. The aim of this study was to investigate the feasibility of using this new type of gel for intensity-modulated radiation therapy (IMRT) verific
Publications Risk Factors For Coronary Artery DiseaseEpiHealth: a large population-based cohort study for investigation of gene-lifestyle interactions in the pathogenesis of common diseasesSleep duration is associated with healthy diet scores and meal patterns: results from the population-based EpiHealth studyBoth Weight at Age 20 and Weight Gain Have an Impact on Sleep Disturbances Later in Life:
https://www.epihealth.lu.se/en/cohort/publications - 2026-09-09
To accomplish these goals we will: A) establish the stimulus-secretion coupling in human pancreatic islets from non-diabetic organ donors to obtain proof of concepts derived from rodent studies; these data will also establish the gold standard for efforts to differentiate embryonic stem cells into mature islet cells. B) Combine islet studies with genetic and metabolic studies in humanA) Our knowle
https://www.ludc.lu.se/welcome-lund-university-diabetes-centre/project-areas/islets - 2026-09-09
Vid elektro-pulsbehandling svarar omedelbart bara de celler som utsätts för ett tillräckligt starkt elektriskt fält. De tumörceller som permeabiliseras blir mycket mer tillgängliga för hydrofila molekyler eftersom dessa normalt avvisas av membranbarriären. Anticancermedlet Bleomycin har visat sig vara det mest potenta läkemedlet i elektropulsbehandling och är det som ofta används i elektro-puls-kIn electro-pulse therapy treatment, only the cells exposed to a sufficiently strong electric field will respond immediately. The tumour cells that are permeabilized become much more accessible to hydrophilic molecules since these are normally rejected by the membrane barrier. The anticancer agent Bleomycin has proven to be the most potent drug in electro-pulse therapy and is the one often used in
Residual stress can be introduced unintentionally into the workpiece with various magnitudes and distributions through all manufacturing processes. These stresses have a significant effect upon the performance of the final component. Understanding the residual stress imparted by machining is an essential aspect of understanding the machining process and overall part quality. Although many investig
Popular Abstract in Swedish Bröstcancer är den typ av cancer som drabbar flest kvinnor i Sverige. Årligen diagnostiseras drygt 7000 kvinnor med bröstcancer och ungefär 1400 dör av sin sjukdom. För att minska bröstcancerdödligheten rekommenderar Socialstyrelsen mammografiscreening där kvinnor över 40 år bjuds in för regelbundna kontroller. Dessa kontroller utförs med digital mammografi som innebär Breast cancer is the most common form of cancer affecting women in the western countries. Today x-ray digital mammography (DM) of the breast is commonly used for early detection of breast cancer. However, the sensitivity of mammography is limited, mainly due to the fact that a 3D volume is projected down to a 2D image. This problem can be partially solved by a tomographic technique. Breast tomosyn
Stora inlandsisar har vid upprepade tillfällen täckt Sveriges yta och den senast inlandsisen började dra sig tillbaka från Bohusläns kust för ca 15 000 år sedan. En inlandsis rör sig sakta framåt över underlaget och när den gör så kan stenar infrusna i isens botten skrapa berggrunden och bilda långa räfflor, flisor kan brytas loss ur berget och stora block kan också frysa fast i isen och transportRamsvikslandet on the Swedish west coast is characterized by exposed bedrock hills with numerous glacial erosional forms. Previous research in the area has mostly focused on individual forms and their relation to the larger forms, such as roches moutonnées. This study takes a more large-scale perspective and aims to reconstruct the subglacial processes based on the erosional forms and their distri
While Fusobacterium necrophorum historically has been considered normal tonsillar flora, recent studies from Europe and the US have suggested that carriage occur transiently in adolescence and young adulthood. However, no studies originating from Africa exist. In this cross-sectional study of tonsillar carriage of F. necrophorum, we aimed to investigate geographical differences in tonsillar carria
The simultaneous multi-species Planar Laser Induced Fluorescence technique plays an important role in studying the flame structure and the two-dimensional distribution of intermediate species in combustion. The experimental system of OH/CH2O/Acetone-PLIF was built in order to study the CH4-Air inverse diffusion jet (IDJ) flame. The system consists of two sets of lasers, two intensifier-CCD cameras
Weak subdivision or fragmentation ability of deformed {100} (<100> // ND, normal direction) grains by traditional unidirectional (symmetric) rolling results in uneven deformation during tantalum (Ta) processing. Thus, a recently developed asymmetric cross rolling (ACR) is adopted in this work to enhance the subdivision of {100} grain in Ta sheets. Electron backscatter diffraction (EBSD), transmiss
Popular Abstract in Swedish I bageriindustrin används emulgatorer i så kallad alfaform för att tårtbottnar ska kunna vispas i ett steg och ändå få en stor luftvolym. Avhandlingen fokuserar på vissa av emulgatorns effekter i produkter såsom kaksmet: Hur skumbildningen påverkas av emulgatormolekylernas packning, hur emulgatorer ändrar svällningen av stärkelsekornen i mjölet, och vilka effekterna bliIn the baking industry, emulsifiers in the alpha-gel state are used for foam formation. This thesis focuses on some parts of the effects of the emulsifier: how the foam formation and foam stability are influenced by the physical state of the emulsifier, how emulsifiers change the gelatinization and gel formation of starch, and the impact that these factors may have in a true product such as a spon
