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Mercury is one of the most toxic elements threatening the biosphere, with levels steadily rising due to both natural and human activities. Selenium is an essential micronutrient, required for normal development and functioning of many organisms. While selenium is known to counteract mercury's toxicity under some conditions, to date information about the mercury-selenium relationship is fragmented
An important contributor to non-exhaust emissions in urban areas is airborne particulate matter originating from brake systems. A well-established way to test such systems in industry is to use inertia dynamometer benches; although they are quite expensive to run. Pin-on-disc tribometers, on the other hand, are relatively cheap to run, but simplify the real system. The literature indicates promisi
Trisomy 7 is a common finding in benign and malignant solid tumors, in several non-neoplastic lesions (for example, osteoarthritis and rheumatoid arthritis), and in apparently normal tissues as well, suggesting that the occurrence of +7 might be associated with factors other than the disease process itself. To find out whether the frequency of +7 varies with a patient's age, we cytogenetically ana
PURPOSE. To examine in rodent models of retinitis pigmentosa (RP) the expression of the neuroprotectants metallothionein-I and -II and of megalin, an endocytic receptor that mediates their transport into neurons. METHODS. Gene and protein expression were analyzed in retinas of rd1 and rds mice and in those of RCS (Royal College of Surgeons) rats of various ages. Glial cell markers (cellular retina
Background: Previous studies in the rat have shown that the spatial organisation of the receptive fields of nociceptive withdrawal reflex (NWR) system are functionally adapted through experience dependent mechanisms, termed somatosensory imprinting, during postnatal development. Here we wanted to clarify 1) if mice exhibit a similar spatial encoding of sensory input to NWR as previously found in t
Background: Sacroiliitis in ankylosing spondylitis has frequently been graded radiographically using the New York (NY) criteria, which also have been applied in computed tomography (CT). Purpose: To validate the grading of the NY criteria in CT of the sacroiliac joints. Material and Methods: With the aid of the NY criteria, assessment of inflammatory and degenerative changes was made in 1304 CT st
INTRODUCTION: Biomarkers play a crucial role in understanding Alzheimer's disease (AD) pathogenesis and treatment effects. However, comparing biomarker measures without standardization and appreciating their magnitude relative to the disease can be challenging. METHODS: To address this issue, we propose the CentiMarker approach, similar to Centiloid, which provides a standardized scale between nor
The food processing industry is integral to modern society, with increasing demands for efficiency and sustainability. Industrial food freezers, such as the JBT Marel’s GyroCompact spiral freezer, are energy-intensive systems operating for extended durations daily, making energy efficiency improvements critical both economically and environmentally. This thesis aims to develop a vision-based monit
Image quality is in essence based on subjective experience, and the involvement of human subjects is therefore necessary in one way or the other in order to make reliable assessments of it. This topic is of interest for Axis Communications AB -- the market leader in surveillance cameras. In this thesis, the softcopy quality ruler method described in ISO 20462 is evaluated through a study of one s
A systematic assessment of radiotherapy for cancer was conducted by The Swedish Council on Technology Assessment in Health Care (SBU) in 2001. The assessment included a review of future developments in radiotherapy and an estimate of the potential benefits of improved radiotherapy in Sweden. The conclusions reached from this review can be summarized as: Successively better knowledge is available o
Popular Abstract in Swedish Varje dag bildas ca 10^12 nya blodceller i människokroppen. Denna enorma produktion av celler utgår från benmärgen och pågår under hela vårt liv. Ytterst sett är denna process beroende av en till antalet liten cellpopulation av sk blodstamceller eller hematopoietiska stamceller. Den enorma potential som vilar i detta system illustreras av det faktum att en enda blodstamHematopoietic stem cells (HSCs) reside in the bone marrow (BM) of adult individuals and are ultimately responsible for the continuous production of blood cells throughout life. The regulation of HSCs in vivo is tightly regulated by both intrinsic and extrinsic factors. The Smad-signaling pathway is an evolutionary conserved signaling circuitry with critical functions during embryogenesis and throu
Populärvetenskaplig sammanfattning: Echinodermerna räknas som en mycket viktig del av den marina faunan. Bland echinodermerna återfinns djur som sjöstjärnor, sjöborrar, ormstjärnor och sjöliljor. Gemensamt för dessa är att de alla byggs upp av ett skelett av mindre delfragment, plåtar, där byggnadskomponenten för själva "skelettet" är kalcit. Kalcit är ett mineral som förekommer som en vPhosphatization of late Early Ordovician echinoderm fragments from N Öland has resulted in excellent preservation of the echinoderm stereom ultra structure. The stereom investigated shows a close relationship to different types found in recent echinoderms. The several different types of phosphatic preservation found have been controlled by diagenetic relationships. The original stereom structures
A random labyrinth is a disordered environment of scatterers on a lattice. A beam of light travels through the medium, and is reflected off the scatterers. The set of illuminated vertices is studied, under the assumption that there is a positive density of points, called `normal points', at which the light behaves in the manner of a simple symmetric random walk. The ensuing `random walk in a labyr
Popular Abstract in Swedish Inflammatoriska luftvägssjukdomar såsom astma och rinit är några av de folksjukdomar som trots den moderna läkarvetenskapen uppvisat en ökad prevalens de senaste decennierna. En allergisk reaktion och efterföljande inflammation tros ligga bakom många av de förändringar som karakteriserar astmatiska luftvägar tex infiltration av vita blodkroppar och extravasering av plasEpithelial damage may contribute to the pathology in airway diseases such as asthma and rhinitis. However, the distribution of epithelial shedding in inflammatory airway diseases and, particularly, the ensuing repair processes are largely unknown. In the present studies we have developed novel in vivo techniques to explore epithelial repair mechanisms and associated tissue responses occuring in gu
The excitation function and momentum distribution of η′ mesons have been measured in photoproduction off Nb93 in the energy range of 1.2-2.9 GeV. The experiment has been performed with the combined Crystal Barrel and MiniTAPS detector system, using tagged photon beams from the ELSA electron accelerator. Information on the sign and magnitude of the real part of the η′-Nb potential has been extracte
The Whooper Swan Cygnus cygnus was a rare breeding species in Sweden during the early years of the 20th century, when total numbers likely consisted of only 20 pairs. Recent decades have however seen a marked increase in numbers and a spread in the swans’ distribution, with the number of pairs breeding in the two northernmost provinces rising from 310 to 2,700 pairs between two main surveys, in 19
Using particle-in-cell simulations, we demonstrate an improvement of the target-normal-sheath acceleration (TNSA) of protons in non-periodically nanostructured targets with micron-scale thickness. Compared to standard flat foils, an increase in the proton cutoff energy by up to a factor of two is observed in foils coated with nanocones or perforated with nanoholes. The latter nano-perforated foils
The third moment cumulant for the aggregated multivariate claims is considered. A formula is presented for the general case when the aggregating variable is independent of the multivariate claims. It is discussed how this result can be used to obtain a formula for the third cumulant for a classical model of multivariate claims. Two important special cases are considered. In the rst one, multivaria
This paper presents a new technique to coordinate distributed load switching in order to restore the voltage during disturbed conditions. The technique of today is mainly based on load shedding, but the restoration of the load is manually controlled. With increased and intelligent signal analysis in the distribution and transmission systems it is possible to switch load automatically, both on and
Prenatal diagnosis in the third pregnancy of a mother who already had one healthy son and one son with Fanconi anaemia (FA), revealed that her fetus was also affected with FA. At 22 weeks a maternal complaint about excessive fetal kicking starting at 15 weeks, focused our attention on the behaviour of the fetus, which was observed by means of real-time ultrasound for 30 min. The differentiation of
