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Background: It has been suggested that changes in prostate-specific antigen (PSA) over time (ie, PSA velocity [PSAV]) aid prostate cancer detection. Some guidelines do incorporate PSAV cut points as an indication for biopsy. Objective: To evaluate whether PSAV enhances prediction of biopsy outcome in a large, representative, population-based cohort. Design, setting, and participants: There were 27
The aim of this thesis was to contribute to the understanding of aspects related to home, health and participation for community living people with disability and identify different groups with different needs for interventions. Study I used focus groups to explore aspects of importance for participation. Twenty-nine people with Parkinson’s Disease participated in nine focus groups. Studies II-III
Objectives: To compare collagenase injections and surgery (fasciectomy) for Dupuytren's contracture (DC) regarding actual total direct treatment costs and short-term outcomes. Design: Retrospective cohort study. Setting: Orthopaedic department of a regional hospital in Sweden. Participants: Patients aged 65 years or older with previously untreated DC of 30 degrees or greater in the metacarpophalan
The aim of this Master's thesis is to explore the function of public libraries as arenas for young people's artistic creations. It examines how the public library makes activities based on independent creativity visible, and what activities of this sort imply to the public library. The thesis also relates this to the public library's task in society. The main object of examination is D
Det här arbetet har genomförts som en fallstudie där transportförpackningarna, wellpapplåda och returback, för Arboga skivbar leverpastej 250 gram har studerats i ett antal olika flöden från produktion och ut till slutanvändare. Datainsamlingen har skett genom intervjuer och observationer hos var och en av de aktörer som ingår i de studerade flödena. Syftet har varit att undersöka hur väl wellpappThis project has been conducted with a case study approach. The studied objects are two different transport packages for the product Arboga skivbar leverpastej 250 gram, which is a Swedish liver paste. One of the transport packages is made of corrugated cardboard while the other one is a returnable plastic box that can be used over and over again. The packages have been studied during their way fr
Syftet med denna uppsats är att studera hur efterlevande makes arvsrätt och andra ekonomiska skyddsregler vid händelse av den ena makens död är uppbyggda. Syftet är även att ur ett genusperspektiv analysera denna lagstiftning för att på så sätt få en djupare förståelse för varför reglerna är konstruerade på detta specifika sätt. För att kunna diskutera genusaspektens påverkan på den svenska lagstiThe purpose of this paper is to study how the surviving spouse’s inheritance rights and other financial guarantees in case of death of the other spouse are constructed and from a gender perspective’s analyse this legislation in order to gain a deeper understanding of why the rules are designed in this specific way. In order to discuss the gender perspectives impact on the Swedish law it’s importan
Our understanding of the society and the world around us is partly communicated to us through the newsmedia. The language used, both written, oral and images, affects the way that we talk about, understand and act upon certain events. In a newsbroadcast there are several interpretations and representations, all communicated in various forms of language, and this language will in turn be the basis
Hanöbuktens utveckling under den senaste istiden har studerats med hjälp av borrkärnor från IODP’s Baltic Sea Palaeoenvironment expedition i Östersjön. Genom att analysera förekomsten av IRD, korrelera en varvig enhet till Ringbergs (1991) regionala lervarvskronologi från sydöstra Sverige, göra pollenanalyser och glödförlustbestämningar har en del luckor i Hanöbuktens historia fyllts i. I borrkärnThe development of Hanö Bay during the last ice age has been investigated by analyzing cores from IODP’s Balitc Sea Palaeoenvironment expedition in the Baltic Sea. By analyzing the presence of Ice Rafted Debris, correlating one of the varved clay units to Ringbergs (1991)regional varve chronology from southeastern Sweden, analyzing pollen grains and measuring loss on ignition a few gaps in the his
Methods: A randomized, double-blind, active-comparator study of patients with type 2 diabetes mellitus inadequately controlled (HbA1c 6.5-8.5%) by metformin monotherapy. Patients received vildagliptin (50 mg twice daily) or glimepiride (up to 6 mg/day) added to metformin. Results: In all, 3118 patients were randomized (vildagliptin, n = 1562; glimepiride, n = 1556). From similar baseline values (7
Background: Cardiac rehabilitation improves prognosis after an acute myocardial infarction (AMI), however, the optimal method of implementation is unknown. The aim of the study was to evaluate the effect of individually-tailored, nurse-led cardiac rehabilitation on patient outcomes. Method: This single-centre retrospective observational study included 217 patients (62±9years, 73% men). All patient
Ever since Brunnby Church was first erected it has been altered and it has crossed boundaries in terms of both religious and national affiliation - from a Catholic to a Lutheran place of worship and from being a Danish to being a Swedish church. The boundaries around and within the church itself have changed, and have become displaced as new forms of worship have been introduced. Boundaries and in
Background: The survival for patients with atrioventricular septal defect has improved markedly over the last decades and, during the same period, the survival of children with Down's syndrome has also increased. The aim of our study was to investigate long-term survival in patients having atrioventricular septal defect with common valvar orifice, but without associated significant congenital hear
Purpose: Inter-individual variation in median plasma copeptin is associated with incident type 2 diabetes mellitus, progression of chronic kidney disease, and cardiovascular events. In this study, we examined whether 24-h urine osmolality was associated with plasma copeptin and whether increasing daily water intake could impact circulating plasma copeptin. Methods: This trial was a prospective stu
Background: C3 is highly expressed in human and rodent pancreatic islets, which secrete insulin to regulate blood glucose homeostasis. We have previously shown that cytosolic C3 protects pancreatic beta-cells from stress, by allowing cytoprotective autophagy, and that the same intracellular pool of C3 also protects beta-cells from cytokine-induced apoptosis. Methods: We now generated a beta-cell s
Background: Postoperative lymph node irradiation can affect shoulder morbidity in breast cancer patients, yet widely accepted dose-volume constraints for the shoulder joint are lacking. The SENOMAC trial randomized patients with breast cancer and 1–2 sentinel lymph node (SLN) macrometastases to axillary lymph node dissection (ALND) or SLN biopsy only. We aimed to analyze the association between th
The evacuation of hospitals in the event of fires and similar emergencies can be a difficult endeavor. Patients usually require assistance, with a considerable number of them being unable to evacuate by themselves due to medical conditions or due to the treatment they are receiving. Assistance is to be provided by the healthcare staff in the affected ward, which means that their level of preparedn
The purpose of this master´s thesis was to investigate the role and function of the annual reports of public libraries: for what purpose are they put together and how are they evaluated and utilised. The study presents different views on the structure and content of library annual reports. Focusing on a specific public library and its municipal administration, the authors identify and describe pro
Title Incentives in a Common Agency: An Experiment Author Roy Forsberg Seminar date 2007-01-31 Tutors Dr. Fredrik Andersson and PhD Tommy Andersson Course Master Thesis in Economics – 10 Swedish credits (15 ECTS) Purpose Analyze the make-or-buy decision from a microeconomic perspective by combining modern common agency theory with the theory of incentives and game theory. From this I hope to conve
In the last few years the airline industry had experienced a rapid growth within the low cost segment. The expenses for the airline companies have during the same period increased, mostly due to higher fuel prices and higher capital costs for airplanes. As a result of this, the economic situation for the airline companies has come to be very strained. The Swedish Civil Aviation Authority (LFV), wh
Geofysiska metoder används vid alla tunnelbyggnadsprojekt då geotekniska beskrivningar och modeller baseras på resultat från dessa. Detaljerade redogörelser för markförhållanden och information om djupet till berggrunden är av intresse, och med geofysiska metoder kan dessa parametrar utvärderas. Detta arbete är baserat på geofysiska undersökningar med fokus på de geoelektriska metoderna. MetodernaIn all tunnel construction projects geophysical methods are important as a foundation for engineering geological conceptual models. Detailed information about the condition and the physical properties of rocks at depth is desirable, and geophysical methods have the potential to exploit these properties. This work is based on geophysical investigations with focus on the geoelectrical methods. The m
