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Intraosseous blood flow of the everted or laterally-retracted patella during total knee arthroplasty

Patellofemoral problems are relatively common sequelae of total knee arthroplasty (TKA), and many factors contribute to these complications. Vascular compromise has been identified as a possible contributing factor, and was selected for further investigation in the present study. Laser Doppler Flowmetry was used to quantify patella intraosseous blood flow in vivo during TKA surgery without the use

Palynostratigraphy of the Triassic-Jurassic transition in southern Sweden

Palynological samples from Upper Triassic and Lower Jurassic exposures and borehole sections of the Hoganas and Rya formations (Fm), NW Skane (Sweden), exhibit diverse and generally well-preserved palynomorph assemblages that can be divided into four miospore zones (from bottom to top): (1) the informal "Topmost upper Rhaetian" zone of Lund; (2) the TSI assemblage zone which spans the Triassic-Jur

No association of the IRS1 and PAX4 genes with type I diabetes

To reassess earlier suggested type I diabetes (T1D) associations of the insulin receptor substrate 1 (IRS1) and the paired domain 4 gene (PAX4) genes, the Type I Diabetes Genetics Consortium (T1DGC) evaluated single-nucleotide polymorphisms (SNPs) covering the two genomic regions. Sixteen SNPs were evaluated for IRS1 and 10 for PAX4. Both genes are biological candidate genes for T1D. Genotyping wa

Simulations and density functional calculations of surface forces in the presence of semiflexible polymers

We simulate interactions between adsorbing and nonadsorbing surfaces immersed in solutions containing monodisperse semiflexible chains. Apart from the nature of the surfaces, we investigate responses to changes of the intrinsic chain stiffness, the degree of polymerization, and the bulk concentration. Our simulations display a sufficient accuracy and precision to reveal free-energy barriers that a

Current European practice in immune tolerance induction therapy in patients with haemophilia and inhibitors.

The management of patients with inhibitors is an important challenge in haemophilia care. The lack of randomized controlled trials means that clinical decisions are generally based on subjective opinions, and purchasers' attention is likely to focus on the costs of treatment. In order to assess the current management of inhibitor patients and use of immune tolerance induction therapy (ITI) in Euro

Optimizing a GC-MS method for screening of Stachybotrys mycotoxins in indoor environments.

Presence of Stachybotrys chartarum in indoor environments has been linked to building-associated disease, however, the causative agents are unknown. Verrucarol (VER) and trichodermol (TRID) are hydrolysis products of some major S. chartarum mycotoxins, i.e. macrocyclic trichothecenes and trichodermin. We optimized gas chromatography-mass spectrometry (GC-MS) methods for detecting VER and TRID in S

Investigation of the Effects of Leaching on the Scaling Resistance of Concrete

Damage to the concrete surface can be observed at the waterline of hydraulic structures in fresh water bodies in cold climates. Gradual deterioration of the concrete surface leads to exposure of coarse aggregate. Superficial damage at the waterline is commonly assumed to be caused by drifting ice floes. However, deterioration of concrete at the waterline may also involve leaching and frost action.