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Optimization of multi-channel neutron focusing guides for extreme sample environments

In this work, we present and discuss simulation results for the design of multi-channel neutron focusing guides for extreme sample environments. A single focusing guide consists of any number of supermirror-coated curved outer channels surrounding a central channel. Furthermore, a guide is separated into two sections in order to allow for extension into a sample environment. The performance of a g

Oncogenic activation of FOXR1 by 11q23 intrachromosomal deletion-fusions in neuroblastoma

Neuroblastoma tumors frequently show loss of heterozygosity of chromosome 11q with a shortest region of overlap in the 11q23 region. These deletions are thought to cause inactivation of tumor suppressor genes leading to haploinsufficiency. Alternatively, micro-deletions could lead to gene fusion products that are tumor driving. To identify such events we analyzed a series of neuroblastomas by comp

Fate of citalopram during water treatment with O(3), ClO(2), UV and fenton oxidation

In the present study we investigate the fate of citalopram (CIT) at neutral pH using advanced water treatment technologies that include O(3), ClO(2) oxidation, UV irradiation and Fenton oxidation. The ozonation resulted in 80% reduction after 30min treatment. Oxidation with ClO(2) removed>90% CIT at a dosage of 0.1mgL(-1). During UV irradiation 85% reduction was achieved after 5min, while Fenton w

Matching and mismatching between the pedagogical design principles of a maths game and the actual practices of play

The article reports and discusses a long-term qualitative study of forty 8-10 year old students who regularly played a math game during math lessons for 9 weeks. The goal was to explore the relations between (i) some of the pedagogical principles that underlie the game and (ii) the playing practice in terms of what actually takes place when students play the math game during regular math lessons.

The need to unify neuropathological assessments of vascular alterations in the ageing brain Multicentre survey by the BrainNet Europe consortium

Here, we summarise the results after carrying out a large survey regarding the assessment of vascular alterations, both vessel changes and vascular lesions in an inter-laboratory setting. In total, 32 neuropathologists from 22 centres, most being members of BrainNet Europe (BNE), participated by filling out a questionnaire with emphasis on assessment of common vascular alterations seen in the brai

Size-Dependent Effects of Nanoparticles on Enzymes in the Blood Coagulation Cascade.

Nanoparticles (NPs) are increasingly used in diagnostic and drug delivery. After entering the bloodstream, a protein corona will form around NPs. The size and curvature of NPs is one of the major characteristics affecting the composition of bound protein in the corona. Key initiators of the intrinsic pathway of blood coagulation, the contact activation complex, (Kallikrein, Factor XII, and high mo

The association between office design and performance on demanding cognitive tasks

The physical office environment has been shown to be associated with indicators of both health and performance. This study focuses on how memory performance is affected in normal working conditions compared to a quiet baseline (with low amount irrelevant stimuli) in different office types, including individual office rooms, small open-plan offices, medium-sized open-plan offices and large open-pla

Configuring anion-exchange membranes for high conductivity and alkaline stability by using cationic polymers with side chains

Polymeric anion-exchange membranes (AEMs) are critical components for alkaline membrane fuel cells (AMFCs) which offer several attractive advantages including the use of platinum-free catalysts and a wide choice of fuel. The development of AMFCs and other electrochemical energy systems is currently severely limited by the lack of AEMs with sufficient alkaline stability. Still, significant advances

Networks for the e-society

The 14th edition of International Telecommunications Network Strategy and Planning Symposium (shortly: Networks 2010) held in Warsaw, Poland. Networks 2010 was a four-day professional and scientific event organized by Warsaw University of Technology in co-operation with Polish Association of Telecommunication Engineers (SIT). The conference was focused on network design and planning methods includ

The accuracy of migration distance measures

The spatial dimension in the definition of internal migration usually refers to the distance someone has tomove to be regarded as a migrant. Lack of precise data on migration distances, however, has obliged migration researchers to use aggregate distance measures whose accuracy is largely unknown, raising potentially serious validity concerns for research. The aim of this paper is to examine the a