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Introduction: For fast and effective antibiotic therapy of serious infections like sepsis, it is crucial with rapid information about antibiotic susceptibility, especially in a time when the number of infections caused by multi resistant bacteria has escalated in the world. Methods: Here, we have used a semi-quantitative MALDI-TOF-MS based method for antibiotic resistance detection, MBT-ASTRA™, wh
Governance and management in publicly funded services includes the processes that governments use to ensure that the activities of organizations involved in the delivery of public services are in line with those expected. In hospital care, the reimbursement model is viewed as an important tool to motivate providers to act in the interest of the funding body. The purpose of this study was to analys
Background: Swallowing dysfunction is an increasingly recognized problem in patients with dementia with Lewy bodies (DLB) and Parkinson’s disease dementia (PDD), which can result in aspiration pneumonia and death. Few studies have examined potential ways of improving swallowing function in this fragile patient group. The aim of this study was to evaluate swallowing dysfunction and carbonated liqui
While social learning has been demonstrated in species across many taxa, the role it plays in everyday foraging decisions is not well understood. Investigating social learning during foraging could shed light on the emergence of cultural variation in different groups. We used an open diffusion experiment to examine the spread of a novel foraging technique in captive Amazon parrots. Three groups we
This dissertation focuses on how to use prototyping as a method for developing models in Management Accounting and Control Systems, a field in Business Administration. It combines three emerging theories: prototyping, Activity Based Costing (ABC) and the Balanced Scorecard (BSc). Prototyping is an alternative to the traditional systems development method. In prototyping end-users play an important
We show that Earth’s sedimentary strata can provide a record of the collisional evolution of the asteroid belt. From 1652 kg of pelagic Maiolica limestone of Berriasian–Hauterivian age from Italy, we recovered 108 extraterrestrial spinel grains (32–250 μm) representing relict minerals from coarse micrometeorites. Elemental and three oxygen isotope analyses were used to characterize the grains, pro
The global extraction of minerals is commonly located in areas populated by indigenous people; and while conflicts between multinational corporations and local activists and indigenous people are widespread today, the understanding of their dynamics are lacking. The Swedish government’s encouragement to an expanding mining industry has caused resistance due to environmental and social implications
Problems with bottlenecks in district heating networks occur when the pipes have too small dimensions to sufficiently meet customer needs. This may result in insufficient differential pressure in DH areas attached to these pipes. Bottlenecks are especially common in expanding DH networks, as previously sufficient pipe diameters may become too small when more DH consumers are connected to the DH ne
Cryogels have potential for applications in water and wastewater treatment. However, maximum levels of exposure to both incorporated materials in cryogels (i.e., nanoparticles [NPs]) and monomers, as a result of leakage, must be established before cryogel composites can be implemented in the large-scale treatment of water. Other factors, such as cost and reuse, must also be studied for each specif
Among hereditary colorectal cancer predisposing syndromes, Lynch syndrome (LS) caused by mutations in DNA mismatch repair genes MLH1, MSH2, MSH6 or PMS2 is the most common. Patients with LS have an increased risk of early onset colon and endometrial cancer, but also other tumors that generally have an earlier onset compared to the general population. However, age at first primary cancer varies wit
Denna avhandling behandlar en mängd mikrostrukturella och molekylära lämningar som påträffats i ett antal fossil. Resultaten presenteras i sex vetenskapliga artiklar med det gemensamma syftet att grundligt studera dessa lämningar med hjälp av såväl nya som vedertagna analysmetoder. Avhandlingens huvudsakliga frågeställningar är dels vad denna typ av fossila spår kan säga om de studerade djurens biThis thesis comprises investigations of microstructures and molecular remains, preserved in a variety of fossil specimens. The results are presented in six papers, collectively aiming to thoroughly examine fossil traces of such remains by employing a combination of both established and relatively new analytical methods. The main questions asked are: What can we learn about the biology, ecology and
För varje typ av djur finns en optimal storlek, men större är ofta bättre. För 300 miljoner år sedan var jättelika drakeflugor de största insekterna någonsin. Högre atmosfäriska syrekoncentrationer tros ha tillåtit dem att både flyga och utvecklas till jättar. Men idag är de största sländorna inte större än en mänsklig hand och tar decennier att utvecklas till vuxna. Men varför blir kråkmått eller
Acute myocardial infarction (AMI) is a disease associated with high morbidity and mortality. Currently there are no available treatments specifically targeting the post-ischemic myocardial processes that lead to heart failure and recurrent coronary events. The innate immune system plays a central role in the two consecutive phases that follow an acute ischemic event: the inflammatory phase and the
Genome amplification in the form of rings or giant rod-shaped marker chromosomes (RGMs) is a common genetic alteration in soft tissue tumors. The mitotic stability of these structures is often rescued by perfectly functioning analphoid neocentromeres, which therefore significantly contribute to cancer progression. Here, we disentangled the genomic architecture of many neocentromeres stabilizing ma
