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Sulfite oxidase is a mononuclear molybdenum enzyme that oxidises sulfite to sulfate in many organisms, including man. Three different reaction mechanisms have been suggested, based on experimental and computational studies. Here, we study all three with combined quantum mechanical (QM) and molecular mechanical (QM/MM) methods, including calculations with large basis sets, very large QM regions (80
Background: Sonographers have a high risk of musculoskeletal disorders. Sonography involves strenuous postures in the neck and upper limbs, and is visually demanding. Echocardiography is especially challenging, with static postures and monotonous movements. Aim: The overall aim of this thesis was to identify ergonomic risk factors for pain in sonographers, and to propose actions for sustainable woBackground: Sonographers have a high risk of musculoskeletal disorders. Sonography involves strenuous postures in the neck and upper limbs, and is visually demanding. Echocardiography is especially challenging, with static postures and monotonous movements. Aim: The overall aim of this thesis was to identify ergonomic risk factors for pain in sonographers, and to propose actions for sustainable wo
The association between somatic cell count (SCC) and daily milk yield in different stages of lactation was investigated in cows free of clinical mastitis (CM). Data were recorded between 1989 and 2004 in a research herd, and consisted of weekly test-day (TD) records from 1,155 lactations of Swedish Holstein and Swedish Red cows. The main data set (data set A) containing 36,117 records excluded TD
Växtätare kan påverka ekosystemprocesser, dels genom långsiktiga förändringar av växtsamhällets sammansättning, men också på kortare sikt genom derasmatspjälkning av organiskt material som cyklas genom markens nedbryderorganismer och tillbaka till de primära producenterna. Särskilt störreväxtätare har studerats i stor utsträckning, men i vissa ekosystem som skogar kan de mindre ryggradslösa växtätHerbivory can influence ecosystem processes, partly through long-term changes of the plant community compositions, but also more rapidly through the herbivores’ digestive alteration of the organic matter that is cycled through the soil and back to the primary producers. In the Subarctic mountain birch (Betula pubescens ssp. czerepanovii) forest (SMBF) in Northern Fennoscandia, outbreaks by the geo
Injurious loading of the joint can be accompanied by articular cartilage damage and trigger inflammation. However, it is not well-known which mechanism controls further cartilage degradation, ultimately leading to post-traumatic osteoarthritis. For personalized prognostics, there should also be a method that can predict tissue alterations following joint and cartilage injury. This chapter gives an
The characterisation of fast phenomena at the microscopic scale is required for the understanding of catastrophic responses of materials to loads and shocks, the processing of materials by optical or mechanical means, the processes involved in many key technologies such as additive manufacturing and microfluidics, and the mixing of fuels in combustion. Such processes are usually stochastic in natu
As versatile compounds forming host-guest complexes with a wide variety of hydrophobic molecules, cyclodextrins are widespread candidates to confer functionalities to surfaces, particularly for drug delivery applications in the field of biomaterials, and for analytic or preparative purposes in separative sciences. We report here on Layer-by-Layer coatings used to decorate surfaces with β-cyclodext
BACKGROUND: Cleaning workers are exposed to chemicals and high physical workload, commonly resulting in airway problems and pain. In this study the response in the upper airways and the physical workload following airborne and ergonomic exposure of cleaning spray was investigated.METHODS: A survey was answered by professional cleaning workers to investigate their use of cleaning sprays and the per
Background: Neurofibrillary tangle pathology is thought to drive neurodegeneration in beta-amyloid positive (A+) cognitively normal (CN) individuals, i.e., preclinical Alzheimer’s disease (AD).However, in beta-amyloid negative (A-) CN, the contribution of tau pathology [primary age-related tauopathy (PART)] to neurodegeneration remains uncertain. We investigate the correlation between tau burden m
OBJECTIVE: To investigate plasma levels of circulating cell-free mitochondrial DNA (ccf-mtDNA) in patients with social anxiety disorder (SAD) and healthy controls (HC).METHODS: In this study, 88 participants (46 patients with SAD and 42 HCs) were enrolled and both ccf-mtDNA and peripheral blood mononuclear cells (PBMC) mtDNA copy number (mtDNA-cn) were measured at up to three times per individual
This work concerns spontaneous fracture of growing brittle precipitates in an elastic plastic matrix. The mass of the precipitate is increasing as more transformed matrix material is added to it. Under stress-free conditions, the new phase occupies a larger volume than the original matrix material. Just outside the expanding precipitate, the matrix undergoes stretching beyond the elastic limit. Th
Republican political theory, with its commitment to a political and personal conception of freedom in terms of the absence of domination, has the potential to revitalize how we think about human rights. From a republican perspective, the aims of the politics of human rights are—in negative terms—to end exploitation, vulnerability, and precarity and—in positive terms—to establish a society of equal
Popular Abstract in English Since the first generation of the Toyota Prius was first introduced in December 1997, the number of Hybrid Electric Vehicles (HEVs) and pure Electric Vehicles (EVs) available in the market has increased substantially, and nowadays almost every car manufacturer has at least one HEV or even EV model within their range. The reason behind this trend relies on the increased Since the first generation of the Toyota Prius was introduced in December 1997, the number of Hybrid Electric Vehicles (HEVs) and pure Electric Vehicles (EVs) available in the market has increased substantially. The growing competition existent puts high demands on the electric system as well as the rest of the vehicle. As a consequence, substantial design effort is devoted to optimize both at sys
Background: Adjuvant chemotherapy is standard treatment for other solid tumours, but to date has not proven effective in prostate cancer. Objective: o evaluate whether six cycles of docetaxel alone improve biochemical disease-free survival after radical prostatectomy for high-risk prostate cancer. Design, setting, and participants: Open-label, randomised multinational phase 3 trial. Enrolment of 4
The ability to detect and quantitate biomolecules in complex solutions has always been highly sought-after within natural science; being usedfor the detection of biomarkers, contaminants, and other molecules of interest. A commonly used technique for this purpose is the Enzyme-linked Immunosorbent Assay (ELISA), where often one antibody is directed towards a specific target molecule, and a second
Avkastningsbaserad gräsrotsfinansiering är en kapitalanskaffningsmetod där små- och nystartade privata aktiebolag via en internetbaserad plattform tar in kapital från många mindre investerare, som i gengäld förvärvar aktier i bolaget. Gräsrotsfinansiering är en effektiv metod, men efter genomförd finansiering är det lilla privata aktiebolaget oftast behäftat med en stor aktieägarkrets, någon som kEquity crowdfunding is when a limited liability company raises capital from a large number of investors whom in return acquire shares in the company. Companies utilize equity crowdfunding to secure funds at an early stage. Equity crowdfunding will however alter the ownership structure of the company to a diversified ownership. In order to maintain its efficiency the company must retain the decisiv
The purpose of this study is to examine how education policies directed towards migrant students are carried out in practice, using a school in Beijing as a case study. Equal education for all is a concept that has come late to China despite the progressive attitudes towards education put forth by Confucius over 3000 years ago. Along with the economic reforms of the 1970’s and China’s emergence in
Den 1 juli 2018 trädde en ny lag om våldtäktsbrottet i kraft baserad på frivillighet. Överväganden kring ett införande av en samtyckesbaserad lagstiftning har pågått och omdebatterats under lång tid och två gånger tidigare har frågan utretts i 1998 års sexualbrottskommitté och 2008 års sexualbrottsutredning. Efter lagändringen 2018 är det tillräckligt med avsaknad av frivillighet vid deltagande i The 1st of July 2018, a new legislation regarding rape came into force, based on consent and voluntary participation. Considerations regarding a consent-based legislation has been ongoing and disputed, not least during the last century and twice before the question has been investigated in the 1998 sex crime committee and the 2008 sex crime investigation. Since the change it is no longer required
Microsoft Word - Staffan Lindberg SASNET homepage December 2016 v2.docx Recent publications: 2016 ‘Back from hell. Marked forever? Trajectory of a Dalit caste in south India.’ Paper for the Seminar for Venkatesh B. Athreya in Chennai, January 2016. Lindberg, S., Athreya, V., Djurfeldt, G., Rajagopal, A., and Vidyasagar, R. Changing Social and Political Relations in the Kaveri Delta. Working paper,
https://www.sasnet.lu.se/sites/sasnet.lu.se/files/recent_publications.pdf - 2026-06-22
