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Popular Abstract in Swedish Blodcirkulationen fungerar i kroppen som ett transport system för proteiner, syre och andra metaboliter. Blodet har den svåra uppgiften att vara flytande och samtidigt kunna koagulera på ställen där kärlet går sönder. Störning i denna balans leder till sjukdomar som hjärtinfarkt och blodpropp eller motsatsen svåra blödningar. Det protein som jag har studerat ingår vid

Renewable energy will play an important role in the transition to a sustainable energy system. With an increased maturity of renewable energy technologies, issues concerning implementation are becoming more important. The decisions and actions of municipalities and other local actors have a significant influence on the implementation of renewable energy. In this thesis challenges to implementation

Sweden, with a high level of political participation and an avant-garde position regarding internet access, broadband and social media penetration in the population, is a critical case for studying social media in relation to political participation. Three types of users – members of political parties, members of interest organizations, and non-members – are interviewed in focus groups about their

The c-kit-encoded tyrosine kinase receptor for stem cell factor (Kit/SCFR) is crucial for the development of hematopoietic cells, melanoblasts, and germ cells. Ligand stimulation of Kit/SCFR leads to receptor dimerization and autophosphorylation on tyrosine residues. We recently showed, that protein kinase C (PKC) acts in an SCF-stimulated negative feedback loop, which controls Kit/SCFR tyrosine k

Kaposi's sarcoma-associated herpes virus (KSHV) encodes a complement inhibitor named KSHV complement control protein (KCP). We have previously shown that KCP inhibits the human complement system by disrupting the C3 convertase of complement. KCP can accelerate the decay of the classical C3 convertase and it can act as a cofactor for factor I (R), which then cleaves and inactivates C4b or C3b (in t

The β-glucosidase TnBgl1A catalyses hydrolysis of O-linked terminal β-glycosidic bonds at the nonreducing end of glycosides/oligosaccharides. Enzymes with this specificity have potential in lignocellulose conversion (degrading cellobiose to glucose) and conversion of bioactive flavonoids (modification of glycosylation results in modulation of bioavailability). Previous work has shown TnBgl1A to hy

Research on the sourcing of siliceous raw materials in Prehistory has taken a step forward with the addition of geochemical techniques and elemental analysis to the archaeopetrological method. Counter to the macroscopic techniques, which retain an elevated subjective percentage in their results, geochemical techniques and especially LA-ICP-MS analysis generate objective, quantifiable and usable da