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Antibodies specific for the antigenic domain 1 of glycoprotein B (gpUL55) of human cytomegalovirus bind to different substructures

Glycoprotein B (gB, gpUL55) is a major antigen for the induction of neutralizing antibodies against human cytomegalovirus, making it an attractive antigen for active and passive immunoprophylaxis. The immunodominant region on gB is the antigenic domain 1 (AD-1), a complex structure which requires a minimal linear amino acid sequence of more than 75 amino acids (aa 552-635) for antibody binding. We

Oral treatment with a vitamin D3 analogue (BXL628) has anti-inflammatory effects in rodent model of interstitial cystitis

To investigate the effects of a vitamin D3 analogue (BXL628) in a model of chronic cystitis, as calcitriol analogues might be an interesting new therapeutic option for interstitial cystitis, for although the cause of the disease remains unclear, the increase in mast cells in the mucosa and detrusor muscle are significant. We devised a mouse model of allergen-induced allergic cystitis that is assoc

Purification of streptococcal protein G expressed by Escherichia coli by high performance liquid affinity chromatography using immobilized immunoglobulin G and albumin

A one-step HPLC method was developed for the purification of protein G, a cell wall molecule from group C and G streptococci with immunoglobulin G- and albumin-binding properties. Lysed Escherichia coli bacteria infected with lambda-phages containing the protein G gene from group G streptococci were used as a starting material for the preparations. The lysate was applied to a column with immobiliz

Antibody-dependent allostery of the M1 protein

Den förrädiska antikroppen Streptokocker är en lömsk bakterie som har många olika sätt att ta sig runt vårt immunförsvar. Den kan låtsas vara en del av vår kropp genom att klä sig själv i en proteinkapsel som är väldigt likt ett mänskligt protein, bryta ned våra celler med hjälp av utsöndrade gifter och använda vårt immunförsvar mot oss genom att binda antikroppar till sig själv. En virulensfaktoThe Group A streptococcus (GAS) (Streptococcus pyogenes) is a significant human pathogen known for causing a diverse range of diseases, spanning from mild diseases such as pharyngitis to life-threatening diseases such as necrotizing fasciitis. Its virulence comes from a plethora of immune evasion mechanisms, but the M protein with its hypervariable region and ability to bind human proteins, stands

Sverker Sikströms publications

Hamade, Jaber, Sikström, S. (2009). Analyzing CAD competence with univariate and multivariate learning curve models. Computers & Industrial Engineering, 56, 1510-1518.Lind, A., Hall, L, Johansson, P., Sikström, S (in press). Can we tell what we said when we hear ourselves saying something else? . Bringing language and cognition back together again. Editors Jordan Zlatev, Mats Andrén, Marlene Johan

https://www.psy.lu.se/sverker-sikstroms-publications - 2026-06-07

Ann-Christine Hartzén

Docent Kontaktinformation E-post: ann-christine [dot] hartzen [at] har [dot] lu [dot] se Telefon: +46 46 222 78 45Organisation Institutionen för handelsrätt Hämtställe: 10 WebbplatsAnn-Christine Hartzéns profil i Lunds universitets forskningsportalAndra roller Forskare Affärsrättsligt centrum vid Lunds Universitet, ACLU Publikationer Visar av publikationer. Sorterade efter år och sen titel. Filtre

https://www.ehl.lu.se/ann-christine-hartzen - 2026-06-08

Från förening till företag - Sportslig kontra ekonomisk framgång

Syftet med uppsatsen är att undersöka vad framgång är i dagens skandinaviska elitfotbollsklubbar och vilka strategier som är användbara för att uppnå denna. Uppsatsen ämnar således belysa och klargöra de viktigaste aspekterna i en lyckad strategi inom en modern skandinavisk fotbollsklubb. Med denna kunskap har vi för avsikt att återge en bild över hur en elitfotbollsklubb strategiskt bör organiser

Redox control of exocytosis - Regulatory role of NADPH, thioredoxin, and glutaredoxin

Cellular redox state is an important metabolic variable, influencing many aspects of cell function like growth, apoptosis, and reductive biosynthesis. In this report, we identify NADPH as a candidate signaling molecule for exocytosis in neuroendocrine cells. In pancreatic beta-cells, glucose acutely raised the NADPH-to-NADP(+) ratio and stimulated insulin release in parallel. Furthermore, intracel

Studies on hereditary C2 deficiency: Frequent occurrence of severe infections, atherosclerosis and rheumatological manifestations

Popular Abstract in Swedish Komplementsystemet utgör en del av den medfödda immuniteten och är viktigt i försvaret mot angripande mikroorganismer. Ärftlig C2-brist (C2D) är en av de vanligaste bristerna inom komplementsystemet och förekommer i en frekvens av 1: 20 000 hos personer med västerländsk härstamning. I de aktuella undersökningarna har mer än 40 personer med C2D identifierats och observerThe complement system is a part of the innate immunity and is essential in the defence against microorganisms. Hereditary C2 deficiency (C2D) is one of the most common complement deficiency states with an estimated prevalence of 1:20,000 in persons of Western descent. In the present investigation, the identification of more than 40 C2D persons at a single centre combined with long observation peri

Khm2 info samlad sv dec18

Konsthögskolans galleri, KHM2, Bergsgatan 29, 3 våning Kontakta Sophie eller respektive tekniker om utrustning du vill låna. Kontakta Kristian i god tid för att planera transporten till lokalen. Samtransport från Khm till Galleriet och lastning av föregående utställningar för tillbakatransport till Khm, på måndag f.m. För att få tillträde till byggnaden, hissen och gallerirummet måste du ha ett LU

https://www.khm.lu.se/en/sites/khm.lu.se.en/files/khm2_info_samlad_sv_dec18.pdf - 2026-06-08

The EU framework programme for research and innovation

Horizon Europe is the EU’s Framework Programme for Research and Innovation for 2021–2027, with a budget of nearly €95.5 billion. The programme offers significant opportunities for researchers at Lund University to secure funding for projects, establish international collaborations and contribute to solutions for global societal challenges. The programme is divided into three main areas:Excellent S

https://www.staff.lu.se/research-and-education/research-support/research-funding/eu-framework-programme-research-and-innovation - 2026-06-07

No title

Object Shift and Event-Related Brain Potentials Mikael Rolla, Merle Hornea, Magnus Lindgrenb Department of Linguistics and Phoneticsa, Department of Psychologyb, Lund University mikael.roll@ling.lu.se 1. Introduction SWEDISH pronominal objects can either precede or follow a sentence adverb, as shown in example (1). In (1a), the pronominal object den ’it’ precedes the sentence adverb inte ’not’, wh

https://projekt.ht.lu.se/fileadmin/user_upload/sol/ovrigt/projekt_gpdb/Roll_Horne_Lindgren_CNS2007.pdf - 2026-06-08

Visit Us

Lund Stem Cell Center (Lunds Stamcellcentrum) is based at Lund University in Sweden, located within the University's Biomedical Centre (BMC) and in close proximity to the Skåne University Hospital. Lund University is located in the city of Lund, close to Malmö (Sweden's third largest city) in the south of Sweden. This part of Sweden is very close to Copenhagen in Denmark.There are several differen

https://www.stemcellcenter.lu.se/lund-stem-cell-center/visit-us - 2026-06-07

Homozygosity for the IgG2 subclass allotype G2M(n) protects against severe infection in hereditary C2 deficiency

Homozygous C2 deficiency (C2D) is the most common deficiency of the classical complement pathway in Western countries. It is mostly found in patients with autoimmune disease or susceptibility to bacterial infections and in healthy persons. We wished to assess to what extent other immunological factors might explain differences of susceptibility to infections in C2D. For this reason, 44 Swedish pat

Arsine, Stibine and Phosphine Derivatives of [Fe2(CO)6(μ-bdt)] (bdt = Benzenedithiolate) : Syntheses, Structures and Spectroscopic and Electrocatalytic Studies

The reactivity of the benzenedithiolate (bdt)-bridged complex [Fe2(CO)6(µ-bdt)] with arsine, stibine and phosphine ligands has been studied. The new mono- and disubstituted complexes [Fe2(CO)5(EPh3)(µ-bdt)] (E = As, 1; E = Sb 3) and [Fe2(CO)4(EPh3)2(µ-bdt)] (E = As, 2; E = Sb, 4) and the previously reported [Fe2(CO)4(PPh2H)2(µ-bdt)] (5) have been prepared by Me3NO-initiated carbonyl substitution r

The IgG-degrading enzyme of Streptococcus pyogenes causes rapid clearance of anti-glomerular basement membrane antibodies in patients with refractory anti-glomerular basement membrane disease

In anti-glomerular basement membrane (anti-GBM) disease, IgG class autoantibodies induce rapidly progressive glomerulonephritis. Regrettably, many patients are diagnosed at a late stage when even intensive conventional treatment fails to restore renal function The endopeptidase IdeS (Immunoglobulin G degrading enzyme of Streptococcus pyogenes) (imliflidase) rapidly cleaves all human IgG subclasses

Enhancing the Accuracy of CSI-Based Positioning in Massive MIMO Systems

Massive Multiple-Input Multiple-Output (MIMO) communication systems are being investigated intensively for positioning services. Enhancing the accuracy on these services in terms of accurate positioning of users is an important goal to improve related applications in the future. Convolutional Neural Networks (CNNs) has been proposed to infer the position of a user from Channel State Information (C